Results 131 to 140 of about 190,436 (297)

Isothiocyanates in medicine: A comprehensive review on phenylethyl-, allyl-, and benzyl-isothiocyanates

open access: yesPharmacological Research
In recent years, isothiocyanates (ITCs), bioactive compounds primarily derived from Brassicaceae vegetables and herbs, have gained significant attention within the biomedical field due to their versatile biological effects. This comprehensive review provides an in-depth exploration of the therapeutic potential and individual biological mechanisms of ...
Cosima C. Hoch   +8 more
openaire   +3 more sources

Benzyl isothiocyanate inhibits murine WEHI-3 leukemia cells in vitro and promotes phagocytosis in BALB/c mice in vivo

open access: yes, 2012
[[abstract]]Benzyl isothiocyanate inhibits murine WEHI-3 leukemia cells in vitro and promotes phagocytosis in BALB/c mice in ...
;Tsou, Mei-Fen;Peng, Ching-Tien;Shil, Mu-Chin;楊家欣;Yang, Jai-Sing;呂啟誠;Lu, Chi-Cheng;江若華;Chiang, Jo-Hua;吳長霖;Wu, Chang-Lin;林景彬;Lin, Jing-Pin;羅琦;Lo, Chyi;范宗宸;Fan, Ming-Jen;鍾景光;Chung, Jing-Gung
core  

ROS‐Responsive Nanoparticle Delivery of Dexmedetomidine Protects the Gut Vascular Barrier After Intestinal Ischemia/Reperfusion via the HDAC‐H3K27ac‐TCF4 Axis

open access: yesAdvanced Science, EarlyView.
A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang   +10 more
wiley   +1 more source

Photoswitchable Ambiphilicity: Light‐Gated Frustrated Lewis Pair Reactivity and Z‐Type Interaction

open access: yesAngewandte Chemie, EarlyView.
Light‐controlled ambiphilicity is realized in photoswitchable intramolecular phosphorus/boron Lewis pairs. Reversible switching modulates both the thermodynamics and kinetics of frustrated Lewis‐pair reactivity, enabling light‐gated CO2 binding and release.
Lennart Stoess   +3 more
wiley   +2 more sources

Toxicological Responses of Confused Flour Beetle, Tribolium confusum du Val (Coleoptera: Tenebrinoidea) to various Isothiocyanate Compounds

open access: yes, 2009
The confused flour beetle, Tribolium confusum du Val (Coleoptera: Tenebrionidae), is one of the most serious pests of stored cereals. The phenyl isothiocyanate resulted in significant mortality on the confused flour beetle with 0.1 and 0.2 mu L ...
DEMİREL, NİHAT   +4 more
core  

Beyond Biomimetics: Pathology‐Informed Engineering Rescues Reconstituted HDL From Inflammatory Dysfunction for Sepsis Immunotherapy

open access: yesAdvanced Science, EarlyView.
A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou   +12 more
wiley   +1 more source

Created Ex Nihilo: A Near‐Infrared Afterglow Luminescent Framework of Imidazole Derivatives for Bioimaging

open access: yesAngewandte Chemie, EarlyView.
A series of Ir(III) complexes (Ir‐1‐Ir‐4) based on imidazole derivatives provide a new afterglow luminescence mechanism. The work expands the range of afterglow luminescence frameworks to overcome: (i) a lack of new afterglow scaffolds; (ii) the dependence on initial external light activation; and (iii) aggregation‐caused quenching.
Zihan Wu   +9 more
wiley   +2 more sources

Efficacy of isothiocyanate-based compounds on different forms of persistent pain

open access: yes, 2018
Elena Lucarini,1 Laura Micheli,1 Alma Martelli,2 Lara Testai,2 Vincenzo Calderone,2 Carla Ghelardini,1 Lorenzo Di Cesare Mannelli1 1Pharmacology and Toxicology Section, Department of Neuroscience, Psychology, Drug Research, and Child Health (Neurofarba),
Martelli A   +6 more
core  

Insights into the mode of action of benzyl isothiocyanate on Campylobacter jejuni.

open access: yes, 2013
International audienceCampylobacter jejuni is a widespread pathogen responsible for most of the food-borne gastrointestinal diseases in Europe. The use of natural antimicrobial molecules is a promising alternative to antibiotic treatments for pathogen ...
Stahl, Martin   +4 more
core   +1 more source

Associations Between Multiple Chemosensory Dysfunction and Cognition

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
Key Points This study supports the association between chemosensory dysfunction and cognition. We introduce methods of assessing trigeminal function with the Medoc TSA‐II thermoprobe. Our results identify an association between subjective trigeminal dysfunction and cognition.
Michelle Yu   +5 more
wiley   +1 more source

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