Results 111 to 120 of about 17,966 (155)

Isothiocyanates in Cancer Prevention

Drug Metabolism Reviews, 2004
Isothiocyanates are sulfur-containing compounds which are largely responsible for the typical flavor of cruciferous vegetables. In animals and humans they are conjugated with glutathione; the first product of this reaction is a dithiocarbamate, which can be ultimately metabolized to the corresponding mercapturic acid, excreted in urine.
Franca, Bianchini, Harri, Vainio
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Synthetic and mechanistic study on the conjugate isothiocyanation of enones with trimethylsilyl isothiocyanate

Organic & Biomolecular Chemistry, 2023
The conjugate isothiocyanation of enones with trimethylsilyl isothioyanate provides excellent yields of β-isocyanato ketones under mild conditions, through a thermodynamically-controlled addition of the thiocyanate anion on the protonated enone.
Yanmei Li, Diana M. Castañeda-Bagatella, Dhyeyi Kakkad, Yongling Ai, Hao Chen, Pier Alexandre Champagne   +5 more
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The clastogenic effects of isothiocyanates

Mutation Research/Genetic Toxicology, 1993
Four isothiocyanates (ITCs), three of which are commonly found in the human diet, were tested for the ability to induce chromosome aberrations in an SV40-transformed Indian muntjac cell line. Whilst allyl ITC was found to be inactive the other three (benzyl ITC, phenethyl ITC and phenyl ITC) were found to be significant inducers of chromosome damage in
S R, Musk, I T, Johnson
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Biological targets of isothiocyanates

Biochimica et Biophysica Acta (BBA) - General Subjects, 2011
Isothiocyanates are phytochemicals with a broad array of effects in biological systems. Bioactivity includes the stimulation of cellular antioxidant systems, induction of apoptosis and interference with cytokine production and activity. Epidemiological evidence and experimental studies indicate that naturally occurring isothiocyanates and synthetic ...
Kristin K, Brown, Mark B, Hampton
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Inhibition of papain by isothiocyanates

Biochimica et Biophysica Acta (BBA) - Enzymology, 1976
During the tapping of papaya latex for papain (EC 3.4.22.2), benzyl isothiocyanate is enzymatically produced from benzylglucosinolate, a major component of the latex fluid. Benzyl isothiocyanate inhibits papain hydrolysis of alpha-N-benzoyl-L-arginine ethyl ester (Bz-Arg-OEt).
C S, Tang, W J, Tang
openaire   +2 more sources

Pharmacokinetics and pharmacodynamics of isothiocyanates

Drug Metabolism Reviews, 2011
Isothiocyanates from Brassica vegetables are of great interest for use in the cure of bacterial infections, as is their potential application in the prevention and treatment of cancer. Although much information is available on their mode of action within the cell, when it comes to the question of whether the necessary pharmacologic concentration has ...
Lamy, Evelyn, Scholtes, Cathy, Herz, Corinna, Mersch-Sundermann, Volker   +3 more
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Tetraalkylammonium Uranyl Isothiocyanates

Inorganic Chemistry, 2012
Three tetraalkylammonium uranyl isothiocyanates, [(CH(3))(4)N](3)UO(2)(NCS)(5) (1), [(C(2)H(5))(4)N](3)UO(2)(NCS)(5) (2), and [(C(3)H(7))(4)N](3)UO(2)(NCS)(5) (3), have been synthesized from aqueous solution and their structures determined by single-crystal X-ray diffraction. All of the compounds consist of the uranyl cation equatorially coordinated to
Clare E, Rowland, Mercouri G, Kanatzidis, L, Soderholm   +2 more
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Structure of isothiocyanate methemoglobin

Journal of Molecular Biology, 1981
Abstract The structure of the complex of the ambidentate ligand thiocyanate with horse methemoglobin was compared with that of acid methemoglobin and azide methemoglobin by X-ray difference Fourier techniques. Thiocyanate is co-ordinated to iron exclusively by its nitrogen atom, and thus forms the isothiocyanate complex.
Z R, Korszun, K, Moffat
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Isothiocyanates of natural derivation

Pure and Applied Chemistry, 1963
Abstract
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Isothiocyanates by Substitution Reactions of Isothiocyanates

2005
S. Braverman, M. Cherkinsky, M. L. Birsa
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