Results 91 to 100 of about 183,701 (312)

Characterisation of naturally occurring isothiocyanates as glutathione reductase inhibitors

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2020
Glutathione reductase (GR), an essential antioxidant enzyme against oxidative stress, has become an attractive drug target for the development of anticancer and antimalarial drugs.
Xia Li, Maowei Ni, Xiaoling Xu, Wei Chen
doaj   +1 more source

isothiocyanates

open access: yes, 2014
Citation: 'isothiocyanates' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.I03320 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Dual‐Responsive Dynamic Covalent Bond‐Based Assembly of Lipid‐Nanozyme Systems via Multi‐Target Synergy and Efficient Target Enrichment for Ischemic Stroke Therapy

open access: yesAdvanced Science, EarlyView.
This system adopts a biomimetic phospholipid structure, covalently binding iNOS inhibitors, neuroprotective agent PCA and vitamin E derivatives through pH/ROS dual‐responsive bonds, and assembles them with Prussian blue nanozyme to form PBB@AHA. It can efficiently penetrate the blood‐brain barrier and simultaneously release multiple active components ...
Mengcheng Guo   +9 more
wiley   +1 more source

Conformational and spectroscopic behaviors of 2,4-xylyl isothiocyanate

open access: yes, 2015
This study aims to identify the conformational and spectroscopic characteristics of 2,4-xylyl isothiocyanate (C9H9NS) compound via experimental and computational methods.
Chand S.   +7 more
core   +1 more source

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

open access: yesAdvanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang   +6 more
wiley   +1 more source

ETHYLENE POLYMERIZATION WITH NICKEL DIIMINE COMPLEXES CONTAINING PSEUDOHALIDES

open access: yesQuímica Nova
Nickel-diimine complexes DADNiX2 (DAD= 2,6-iPr2-C6H3-N=C(Me)-C(Me)=N-2,6-iPr2-C6H3) containing the non-chelating pseudo-halide ligands isothyocyanate and isoseleniumcyanate (X= NCS 1 and NCSe 2) were synthesized and used in ethylene polymerization ...
Marcos L. Dias   +3 more
doaj   +1 more source

Phenethyl Isothiocyanate Induces Ca2+ Movement and Cytotoxicity in PC3 Human Prostate Cancer Cells

open access: yes, 2012
The effect of phenethylisothiocyanate (PEITC), a cruciferous vegetable-derived compound, on cytoplasmic free Ca2+ concentrations ([Ca2+]i) in prostatecells has not been explored.
Chung-Ren Jan;Chen, Chung-Yi;Shu-Chi Wang; Soong-Yu Kuo
core  

Results of serum sinistrin and transcutaneous fluorescein-isothiocyanate-labelled sinistrin clearance in all animals studied.

open access: yes, 2014
(FITC-S = fluorescein-isothiocyanate-labelled sinistrin, k = transfer rate between compartments, Vss = Volume of distribution under steady state conditions).Results of serum sinistrin and transcutaneous fluorescein-isothiocyanate-labelled sinistrin ...
Zeneida Herrera-Pérez (665953)   +7 more
core   +1 more source

Field attraction of Eurydema ornata (Hemiptera: Pentatomidae) to allyl isothiocyanate

open access: yes, 2023
Several Eurydema species (Hemiptera: Pentatomidae) are considered as pests, however, reports on their chemical ecology are scarce. In the current study we focused on Eurydema ornata (Linnaeus) a pentatomid pest of several brassicaceous crops.
Miklós Tóth   +3 more
core   +1 more source

Tailored Porous Bimetallic Nanozyme Platform for Full‐Cycle Therapeutics of Intestinal Ischemia/Reperfusion

open access: yesAdvanced Science, EarlyView.
ABSTRACT Intestinal ischemia/reperfusion (I/R) injury presents a biphasic pathology: an acute oxidative‐inflammatory phase leading to organ failure, and a recovery phase marked by mucosal dysfunction and bacterial translocation. The developed MPB@TA‐Cu‐Ma nanocomposite functions as a dual‐phase therapeutic platform with significant efficacy. It rapidly
Chenghao Qiu   +15 more
wiley   +1 more source

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