Results 101 to 110 of about 183,701 (312)

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

open access: yesAdvanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee   +11 more
wiley   +1 more source

A simple guanidinium isothiocyanate method for bacterial genomic DNA isolation

open access: yes, 2014
A high-quality and low-cost genomic DNA isolation method is needed for use in microbiology laboratories. In this study, we developed a new modified guanidinium isothiocyanate method to isolate DNA from Escherichia coli, Salmonella enterica subsp.
Mozioglu, Erkan   +3 more
core   +1 more source

Developmentally Inspired Bioprinting of Nascent Multicellular Human Heart Tissue Through in Situ Differentiation and Morphogenesis of iPSCs

open access: yesAdvanced Science, EarlyView.
A developmentally inspired bioprinting approach enables the fabrication of pluripotent tissues that undergo shape‐morphing and in situ cardiac lineage specification. This method employs embedded bioprinting to deposit iPSCs within soft granular hydrogels to create pluripotent tissue constructs that undergo cell‐mediated shape morphogenesis.
Ankita Pramanick   +8 more
wiley   +1 more source

Benzyl Isothiocyanate Induces Growth Inhibition and Cell Apoptosis in Human Melanoma A375.S2 Cells

open access: yes, 2010
[[abstract]]Skin cancer is one of the common carcinomatous diseases. It is becoming increasingly common in younger populations.Recently, many reports indicated that increased intake of cruciferous vegetables may be effective in preventing the risk of ...
Liu-Wei Wu
core  

Addition-cyclization reactions of 2-pyridyl isothiocyanate

open access: yes, 1981
Addition-cyclization reactions of 2-pyridyl isothiocyanate with enamines and C-acids afforded derivatives containing pyrido[1,2-a]pyrimidine skeleton. Cyclization with a series of phenylhydrazones gave substituted triazolidines.
Miroslav Marchalín   +2 more
core   +1 more source

A Chirality‐Converted Bacteriolytic Dodecapeptide Regulates Vibrio‐Induced Polymicrobial Infection and Ameliorates Invasion‐Associated Gut Microbiota Disequilibrium

open access: yesAdvanced Science, EarlyView.
Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng   +11 more
wiley   +1 more source

Oxidimetric method of determination of allyl isothiocyanate in black mustard (Brassica nigra L.) with chloramine-T.

open access: yes, 1972
Allyl isothiocyanate is the factor responsible for the pungency and aroma of black mustard. A rapid analytical method has been developed for the determination of the isothiocyanate with chloramine-T. The isothiocyanate is quantitatively converted in acid
Raghavan, B.   +3 more
core  

Vibrational analysis of germyl isothiocyanate and its isotope

open access: yes, 1981
A complete vibrational analysis of the germyl isothiocyanate and its isotope is described in this paper. A general Valence Force Field has been computed for these molecules, belonging to C3v symmetry, using the fundamental frequencies obtained from the ...
Natarajan, A.   +3 more
core   +1 more source

Highly Biomimetic Ectodermal Epithelial Organoids for Epithelial Barrier Stimulation Assays

open access: yesAdvanced Science, EarlyView.
ABSTRACT Evaluating the potential toxicity of pharmaceuticals and biomaterials to ectodermal epithelia, such as the oral mucosa and skin, is indispensable in pre‐clinical assessments. However, this remains a challenge primarily owing to the lack of physiologically relevant and accurate screening models.
Yiming Chen   +13 more
wiley   +1 more source

Volumetric determination of allyl isothiocyanate in black mustard (Brassica nigra).

open access: yes, 1971
A survey of the literature showed that there is no simple quick and reliable analytical method for the estimation of allyl isothiocyanate in mustard.
Chikkaputtaiah, K. S.   +2 more
core  

Home - About - Disclaimer - Privacy