Results 241 to 250 of about 183,701 (312)

Natural Isothiocyanates Block Adhesion and Invasion of Gemcitabine- and Cisplatin-Resistant Bladder Cancer Cell Lines. [PDF]

open access: yesMolecules
Rutz J   +12 more
europepmc   +1 more source

Inter‐Crystal Spacing of Implantable Polymeric Surfaces as a Key Suppressor of Microbial Adhesion.

open access: yesSmall, EarlyView.
Biofilm formation on implantable devices is addressed by controlling inter‐crystal spacing in shape memory polymers. Repeated shape recovery aligns and enlarges crystalline phases and reduces amorphous regions, enhancing bacterial repellency. Three biofilm‐forming bacteria show reduced adhesion, and a one‐year dog bile‐duct model maintains function ...
Kang Suk Lee   +5 more
wiley   +1 more source

Human Colitis‐on‐Chip Model Reveals Dual Roles of Butyrate in Epithelial and Macrophage Defense Against Candida albicans Tissue Invasion

open access: yesSmall, EarlyView.
This study establishes a human immunocompetent colitis‐on‐chip model that mimics inflamed gut mucosa and enables quantitative analysis of Candida albicans tissue invasion under DSS‐induced injury. It reveals that microbiota‐derived butyrate simultaneously stabilizes epithelial junctions and reprograms macrophages via HDAC/NLRP3‐dependent mechanisms ...
Manuel Allwang   +16 more
wiley   +1 more source

Innovative Microneedle Patches for Psoriasis Treatment: A Dual Approach With Methotrexate‐Zinc and Difelikefalin for Enhanced Therapeutic Outcomes

open access: yesSmall, EarlyView.
This study presents a novel dual‐layer microneedle platform for psoriasis treatment, integrating rapid itch relief with sustained immunomodulatory and antibacterial effects. By combining difelikefalin and methotrexate‐zinc, this system effectively targets pruritus, epidermal hyperplasia, immune dysregulation, and infection, offering a promising ...
Xiaolong Xu   +5 more
wiley   +1 more source

Smart cellulose‐based room temperature phosphorescent materials: From mechanisms to construction strategies and applications

open access: yesSmart Molecules, EarlyView.
This review elucidates the photophysical mechanisms of cellulose‐based room temperature phosphorescent materials and systematically outlines their construction strategies, such as cluster emission center engineering. This article demonstrates their applications in fields like information encryption and bioimaging, and looks ahead to the core challenges
Shasha Wu   +10 more
wiley   +1 more source

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