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An Integrated Approach for the Comprehensive Characterization of Metabolites in Broccoli (<i>Brassica oleracea</i> var. <i>Italica</i>) by Liquid Chromatography High-Resolution Tandem Mass Spectrometry. [PDF]
Hu Z +10 more
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Biological Activities of Glucosinolate and Its Enzymatic Product in <i>Moringa oleifera</i> (Lam.). [PDF]
Wang J, Yang S, Shen S, Ma C, Chen R.
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Chemoprevention by isothiocyanates
Journal of Cellular Biochemistry, 1995Naturally occurring and synthetic isothiocyanates are among the most effective chemopreventive agents known. A wide variety of isothiocyanates prevents cancer in the rat lung, mammary gland, esophagus, liver, small intestine, colon, and bladder. Mechanistic studies have shown that this chemopreventive activity is due to favorable modification of phase ...
Stephen Hecht
exaly +3 more sources
INHIBITION OF CARCINOGENESIS BY ISOTHIOCYANATES*
Drug Metabolism Reviews, 2000Isothiocyanates occur as conjugates in a wide variety of cruciferous vegetables. Consumption of normal amounts of these vegetables results in the uptake of substantial quantities of isothiocyanates. These naturally occurring isothiocyanates as well as many synthetic analogs can be powerful inhibitors of carcinogenesis in laboratory animals ...
Stephen Hecht
exaly +3 more sources
Isothiocyanates in Cancer Prevention
Drug Metabolism Reviews, 2004Isothiocyanates are sulfur-containing compounds which are largely responsible for the typical flavor of cruciferous vegetables. In animals and humans they are conjugated with glutathione; the first product of this reaction is a dithiocarbamate, which can be ultimately metabolized to the corresponding mercapturic acid, excreted in urine.
Franca, Bianchini, Harri, Vainio
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Synthetic Communications, 1990
Abstract Phosphoryl isothiocyanate, PO(NCS)3, reacts readily with tertiary alcohols and carboxylic acids, giving the respective tertiary isothiocyanates and acyl isothiocyanates in good yields and purity.
Ladislav Kniežo, Juraj Bernát
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Abstract Phosphoryl isothiocyanate, PO(NCS)3, reacts readily with tertiary alcohols and carboxylic acids, giving the respective tertiary isothiocyanates and acyl isothiocyanates in good yields and purity.
Ladislav Kniežo, Juraj Bernát
openaire +1 more source

