Results 211 to 220 of about 13,638 (297)

Cononsolvency‐Assisted Fabrication of Hydrogels and Microgels With Tunable Porosity, Diffusivity and Stiffness

Macromolecular Rapid Communications, EarlyView.
The cononsolvency of poly(dimethyl acrylamide‐co‐hydroxyethyl acrylamide) copolymers in water‐acetonitrile mixtures enables the synthesis of hydrogels with finely tuned porosity. Optimized for droplet‐based microfluidics, this approach facilitates the fabrication of porous microgels with tunable mechanical and diffusion properties, offering precise ...
Maria I. Pieper, Daniel D. Stöbener, Bernhard Häßel, Richard Hoogenboom, Andrij Pich   +4 more
wiley   +1 more source

Anticancer Potential of Cucurbitaceae, Brassicaceae, Liliaceae and Chenopodiaceae: A Review of In Vitro Evidence. [PDF]

Molecules
Blanco-Torres EC, Rivera G, Delgado-Maldonado T, Ortiz-Pérez E, Paz-González AD, Martínez-Vázquez AV, De Luna-Santillana EJ, Ortega-Balleza JL, Vázquez-Jiménez LK.   +8 more
europepmc   +1 more source

Dehydrocostus Lactone Suppresses Hepatocellular Carcinoma by Inhibiting Protein Tyrosine Kinase‐7 Mediated β‐Catenin Signaling

Phytotherapy Research, EarlyView.
Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan, Junhui Li, Yu Qiao, Yuwen Zhong, Xuecheng Ge, Yaoshuai Zhang, Zishu Wang, Feng Qian, Weixin Ren   +8 more
wiley   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

Serum Molecular Fingerprints of Oxidative Stress Underlying Neurocognitive and Motor Dysfunction in Pesticide-Exposed Populations. [PDF]

Eur J Neurosci
Rabanal-Sanchez J, Silva-Correa CR, Burgos-Flores MA, Mayma-Aguirre KJ, Cainamarks-Alejandro JA, Astete-Cornejo JM, Rosales-Rimache J.   +6 more
europepmc   +1 more source

Brassinin Inhibits Cell Survival and Autophagy via Modulation of ROS Production and the AMPKα‐beclin1 Signaling Pathway in Gliomas

Phytotherapy Research, EarlyView.
Brassinin, a phytoalexin derived primarily from Chinese cabbage, exhibits potent anticancer activity against glioblastoma (GBM). Mechanistically, brassinin treatment elevates intracellular ROS levels in GBM cells, triggering two parallel outcomes: (i) direct induction of apoptosis, and (ii) suppression of cytoprotective autophagy through downregulation
Sunil Rauniyar, Yuhui Wang, Qiaoshan Zhang, Shicheng Zhang, Jiale Yin, Tong Zhang, Shangfeng Gao, Rutong Yu   +7 more
wiley   +1 more source

Mechanisms of <i>Moringa oleifera</i> Leaf Extract Influences Productive Performance, Immunity, Milk Composition, and Rumen Microbiota in Ruminants: A Review. [PDF]

Vet Sci
Abdulrahman MY, Ibrahim NA, Essa MOA, Adam SY, Din RMU, Ahmed AA, Jan RU, Bendif H, Basher NS, Saleh AA, Husien HM, Wang M.   +11 more
europepmc   +1 more source

Hinokitiol Promotes Neural Repair After Spinal Cord Injury by Reprogramming Microglial Inflammatory and Redox Responses

Phytotherapy Research, EarlyView.
Schematic illustration showing that Hinokitiol promotes neural repair after spinal cord injury by activating the Keap1/Nrf2/HO‐1 signaling pathway and reprogramming microglial inflammatory‐redox responses. ABSTRACT Secondary neuroinflammation and oxidative stress, driven partly by maladaptive microglial activation, limit recovery after spinal cord ...
Wenhao Zhang, Jing Wang, Tianyi Wang, Qihao Fu, Jiawen Xu, Chaochen Li, Zheng Zhou, Chenxi Zhang, Guanhua Xu, Mingjie Xia, Zhiming Cui   +10 more
wiley   +1 more source

Dietary cauliflower (Brassica oleracea var. botrytis) mitigates benzo[a]pyrene-induced oxidative stress, immune dysfunction, and tissue damage in Nile tilapia. [PDF]

Sci Rep
El-Bouhy Z, Rahman ANA, Mohamed FAS, Elashhab MWA, Khamis T, Reda RM.   +5 more
europepmc   +1 more source

Notoginsenoside R2 Antagonizes Renal Interstitial Fibrosis by Regulating Fatty Acid Oxidation via the CASP2/ALDH3A1 Axis

Phytotherapy Research, EarlyView.
Proposed mechanism by which notoginsenoside R2 (NGR2) attenuates renal interstitial fibrosis. In injured renal tubular epithelial cells, CASP2 downregulation and enhanced ubiquitin‐dependent degradation of ALDH3A1 disrupt mitochondria‐associated endoplasmic reticulum membranes (MAMs) and impair fatty acid oxidation (FAO), leading to lipid accumulation ...
Guanting Chen, Tao Li, Zhenzhen Wang, Hao Zhao, Xiaoxia Xun, Yijiao Wang, Shiyuan Jiang, Qing Zhang, Weiwei Sun, Kang Yang, Yaoxian Wang   +10 more
wiley   +1 more source