Results 211 to 220 of about 8,383 (261)
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The reaction of fluorescein isothiocyanate with thiols: A method for assay of isothiocyanates
Analytical Biochemistry, 1983The reversible formation of dithiourethanes from fluorescein isothiocyanate and mercaptoethanol or mercaptoethylamine has been studied. It is shown that it is possible to use the reaction as the basis for a spectrophotometric titration of a number of isothiocyanates with mercaptoethanol.
A F, Wilderspin, N M, Green
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Synthesis of Isothiocyanates: An Update
Synthesis, 2019Isothiocyanates (ICTs) are a group of molecules that can be used for many different purposes, they exhibit anticancer, antimicrobial, antibiotic, and anti-inflammatory properties. The synthesis of isothiocyanates has been a focus of many researchers for nearly the past 100 years.
Kayla Eschliman, Stefan Bossmann
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Isothiocyanates and Xenobiotic Detoxification
Molecular Nutrition & Food Research, 2018AbstractThe potential of isothiocyanates to antagonize the carcinogenicity of structurally diverse chemicals has been established in animals. A feasible mechanism of action involves protecting DNA by reducing the availability of the genotoxic metabolites of chemical carcinogens by either inhibiting their generation and/or stimulating their ...
Abdull Razis, Ahmad Faizal +2 more
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Chemopreventive Functions of Isothiocyanates
Drug News & Perspectives, 2005Numerous animal and epidemiological studies have demonstrated that consumption of cruciferous vegetables is inversely correlated with the cancer incidence. Strong anticarcinogenic activities of cruciferous vegetables are attributed to the high abundance of glucosinolates.
Young-Sam, Keum +2 more
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Organic & Biomolecular Chemistry, 2023
The conjugate isothiocyanation of enones with trimethylsilyl isothioyanate provides excellent yields of β-isocyanato ketones under mild conditions, through a thermodynamically-controlled addition of the thiocyanate anion on the protonated enone.
Yanmei Li +5 more
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The conjugate isothiocyanation of enones with trimethylsilyl isothioyanate provides excellent yields of β-isocyanato ketones under mild conditions, through a thermodynamically-controlled addition of the thiocyanate anion on the protonated enone.
Yanmei Li +5 more
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Pharmacokinetics and pharmacodynamics of isothiocyanates
Drug Metabolism Reviews, 2011Isothiocyanates from Brassica vegetables are of great interest for use in the cure of bacterial infections, as is their potential application in the prevention and treatment of cancer. Although much information is available on their mode of action within the cell, when it comes to the question of whether the necessary pharmacologic concentration has ...
Lamy, Evelyn +3 more
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The clastogenic effects of isothiocyanates
Mutation Research/Genetic Toxicology, 1993Four isothiocyanates (ITCs), three of which are commonly found in the human diet, were tested for the ability to induce chromosome aberrations in an SV40-transformed Indian muntjac cell line. Whilst allyl ITC was found to be inactive the other three (benzyl ITC, phenethyl ITC and phenyl ITC) were found to be significant inducers of chromosome damage in
S R, Musk, I T, Johnson
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Biological targets of isothiocyanates
Biochimica et Biophysica Acta (BBA) - General Subjects, 2011Isothiocyanates are phytochemicals with a broad array of effects in biological systems. Bioactivity includes the stimulation of cellular antioxidant systems, induction of apoptosis and interference with cytokine production and activity. Epidemiological evidence and experimental studies indicate that naturally occurring isothiocyanates and synthetic ...
Kristin K, Brown, Mark B, Hampton
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Tetraalkylammonium Uranyl Isothiocyanates
Inorganic Chemistry, 2012Three tetraalkylammonium uranyl isothiocyanates, [(CH(3))(4)N](3)UO(2)(NCS)(5) (1), [(C(2)H(5))(4)N](3)UO(2)(NCS)(5) (2), and [(C(3)H(7))(4)N](3)UO(2)(NCS)(5) (3), have been synthesized from aqueous solution and their structures determined by single-crystal X-ray diffraction. All of the compounds consist of the uranyl cation equatorially coordinated to
Clare E, Rowland +2 more
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Structure of isothiocyanate methemoglobin
Journal of Molecular Biology, 1981Abstract The structure of the complex of the ambidentate ligand thiocyanate with horse methemoglobin was compared with that of acid methemoglobin and azide methemoglobin by X-ray difference Fourier techniques. Thiocyanate is co-ordinated to iron exclusively by its nitrogen atom, and thus forms the isothiocyanate complex.
Z R, Korszun, K, Moffat
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