Results 231 to 240 of about 12,031 (303)

Isothiocyanates as Ferroptosis Inducers to Promote Cancer Cell Death

Phytotherapy Research, EarlyView.
ABSTRACT Cancer remains a leading cause of global mortality, with the therapeutic efficacy of anticancer drugs often hampered by late diagnosis and the development of chemotherapy resistance. Ferroptosis is an iron‐dependent form of regulated non‐apoptotic cell death driven by lipid peroxidation.
Valentina Citi, Renda Chahna, Francesca Maffei, Alma Martelli, Vincenzo Calderone, Carmela Fimognari, Eleonora Turrini   +6 more
wiley   +1 more source

Impact of allyl-isothiocyanate and high sucrose diet on antimicrobial peptide expression and survival in <i>Drosophila melanogaster</i>. [PDF]

Front Immunol
Dähn S, Zimmermann C, Merschmann R, Schmutzler P, Wagner AE.   +4 more
europepmc   +1 more source

2D van der Waals System Integrated with Targeting Radio‐Diagnostic and Imaging Functions

Small, EarlyView.
Layered double hydroxide (LDH) nanoplates were engineered for tumor‐targeted imaging and therapy. By exploiting folate receptor (FR) expression levels, the system achieves selective tumor accumulation and high‐resolution dual PET/fluorescence (PET/FL) imaging.
Sairan Eom, Jae Hun Ahn, Jung Yung Kim, Kyo Chul Lee, Yong Jin Lee, Sanoj Rejinold N, Jin‐Ho Choy   +6 more
wiley   +1 more source

Glucosinolate-Derived Metabolites from <i>Barbarea vulgaris</i> (Brassicaceae): Evaluation of Antimicrobial, Antioxidant, and Anti-Inflammatory Potentials. [PDF]

Molecules
Mavrić-Scholze E, Gusinac A, Dekić M, Palić I, Avdović E, Simijonović D, Grujović M, Marković K, Dobričić V, Bošković J, Marković Z, Radulović N.   +11 more
europepmc   +1 more source

Inter‐Crystal Spacing of Implantable Polymeric Surfaces as a Key Suppressor of Microbial Adhesion.

Small, EarlyView.
Biofilm formation on implantable devices is addressed by controlling inter‐crystal spacing in shape memory polymers. Repeated shape recovery aligns and enlarges crystalline phases and reduces amorphous regions, enhancing bacterial repellency. Three biofilm‐forming bacteria show reduced adhesion, and a one‐year dog bile‐duct model maintains function ...
Kang Suk Lee, Yohan Kim, Jueun Kim, Sungwoo Cho, Dae‐Hyun Kim, Hak‐Joon Sung   +5 more
wiley   +1 more source

Human Colitis‐on‐Chip Model Reveals Dual Roles of Butyrate in Epithelial and Macrophage Defense Against Candida albicans Tissue Invasion

Small, EarlyView.
This study establishes a human immunocompetent colitis‐on‐chip model that mimics inflamed gut mucosa and enables quantitative analysis of Candida albicans tissue invasion under DSS‐induced injury. It reveals that microbiota‐derived butyrate simultaneously stabilizes epithelial junctions and reprograms macrophages via HDAC/NLRP3‐dependent mechanisms ...
Manuel Allwang, Maximilian Wipplinger, Parastoo Akbarimoghaddam, Raquel Alonso‐Roman, Zoltan Cseresnyes, Axel Dietschmann, Valentin Wegner, Adrian Feile, Yann Bachelot, Maria Warschinke, Mohamed I. Abdelwahab Hassan, Sonnhild Mittag, Otmar Huber, Bernhard Hube, Mark S. Gresnigt, Marc Thilo Figge, Alexander S. Mosig   +16 more
wiley   +1 more source

Supercritical Fluid Extraction to Valorise Fruit and Vegetable by-Products. [PDF]

Foods
De Feo M, Conte A, Del Nobile MA.
europepmc   +1 more source

Innovative Microneedle Patches for Psoriasis Treatment: A Dual Approach With Methotrexate‐Zinc and Difelikefalin for Enhanced Therapeutic Outcomes

Small, EarlyView.
This study presents a novel dual‐layer microneedle platform for psoriasis treatment, integrating rapid itch relief with sustained immunomodulatory and antibacterial effects. By combining difelikefalin and methotrexate‐zinc, this system effectively targets pruritus, epidermal hyperplasia, immune dysregulation, and infection, offering a promising ...
Xiaolong Xu, Chunhao Long, Yuze Zhou, Lujing Fei, Youyou Zhou, Min Qi   +5 more
wiley   +1 more source

An Integrated Approach for the Comprehensive Characterization of Metabolites in Broccoli (<i>Brassica oleracea</i> var. <i>Italica</i>) by Liquid Chromatography High-Resolution Tandem Mass Spectrometry. [PDF]

Plants (Basel)
Hu Z, Yan M, Song C, Sato M, Su S, Lin S, Li J, Zou H, Tang Z, Hirai MY, Yan X.   +10 more
europepmc   +1 more source

Smart cellulose‐based room temperature phosphorescent materials: From mechanisms to construction strategies and applications

Smart Molecules, EarlyView.
This review elucidates the photophysical mechanisms of cellulose‐based room temperature phosphorescent materials and systematically outlines their construction strategies, such as cluster emission center engineering. This article demonstrates their applications in fields like information encryption and bioimaging, and looks ahead to the core challenges
Shasha Wu, Yifan Zhou, Wanjin Wu, Yan Tang, Mengfan Jing, Jianyu Zhang, Haoke Zhang, Zheng Zhao, Junwei Wang, Laurent Maron, Lijie Liu   +10 more
wiley   +1 more source