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Isothiocyanates as Ferroptosis Inducers to Promote Cancer Cell Death. [PDF]

open access: yesPhytother Res
Citi V   +6 more
europepmc   +1 more source
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Chemoprevention by isothiocyanates

Journal of Cellular Biochemistry, 1995
Naturally occurring and synthetic isothiocyanates are among the most effective chemopreventive agents known. A wide variety of isothiocyanates prevents cancer in the rat lung, mammary gland, esophagus, liver, small intestine, colon, and bladder. Mechanistic studies have shown that this chemopreventive activity is due to favorable modification of phase ...
Stephen Hecht
exaly   +3 more sources

A Convenient Synthesis of Tertiary Isothiocyanates and Acyl Isothiocyanates Using Phosphoryl Isothiocyanate

Synthetic Communications, 1990
Abstract Phosphoryl isothiocyanate, PO(NCS)3, reacts readily with tertiary alcohols and carboxylic acids, giving the respective tertiary isothiocyanates and acyl isothiocyanates in good yields and purity.
Ladislav Kniežo, Juraj Bernát
openaire   +1 more source

INHIBITION OF CARCINOGENESIS BY ISOTHIOCYANATES*

Drug Metabolism Reviews, 2000
Isothiocyanates occur as conjugates in a wide variety of cruciferous vegetables. Consumption of normal amounts of these vegetables results in the uptake of substantial quantities of isothiocyanates. These naturally occurring isothiocyanates as well as many synthetic analogs can be powerful inhibitors of carcinogenesis in laboratory animals ...
Stephen Hecht
exaly   +3 more sources

The reaction of fluorescein isothiocyanate with thiols: A method for assay of isothiocyanates

Analytical Biochemistry, 1983
The reversible formation of dithiourethanes from fluorescein isothiocyanate and mercaptoethanol or mercaptoethylamine has been studied. It is shown that it is possible to use the reaction as the basis for a spectrophotometric titration of a number of isothiocyanates with mercaptoethanol.
A F, Wilderspin, N M, Green
openaire   +2 more sources

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