Results 261 to 270 of about 57,431 (346)

Defining AV2‐1 as a novel pharmacological probe to target human and rodent TRPV2

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Transient receptor potential vanilloid 2 (TRPV2) is a non‐selective cation channel implicated in immune cell functions. However, progress in understanding TRPV2 has been limited by a lack of potent and selective pharmacological tools, particularly those targeting the human variant. We aimed to identify and characterise a
Andrea Leipe, Julia A. Rocereta, Ruth A. Pumroy, Andreas Leffler, Michael Schaefer, Vera Moiseenkova‐Bell, Kerstin Hill   +6 more
wiley   +1 more source

Synthesis and Evaluation of Pseudoglucosinolates Releasing Isothiocyanates in the Presence of Azoreductases. [PDF]

Chembiochem
Chakrabarti A, Ganskow CSG, Kagho MD, Jimidar CC, Wiese L, Beyazit N, Beutling U, Seeger M, Smits S, Nyström S, Farewell A, Schallmey A, Brönstrup M, Klahn P.   +13 more
europepmc   +1 more source

Contact sensitisers activate keratinocytes and induce cytotoxicity via Transient Receptor Potential Ankyrin 1 in allergic contact dermatitis

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Allergic contact dermatitis (ACD) is a frequent inflammatory skin disease with limited therapeutic options. While neuronal Transient Receptor Potential Ankyrin 1 (TRPA1) has been implicated in ACD, the role of keratinocyte TRPA1 remains unclear.
Areej Jaber, Szabina Horváth, Balázs Zoltán Zsidó, Viktória Kormos, János Konkoly, Csaba Hetényi, Erika Pintér, Ágnes Kemény, Rolland Gyulai   +8 more
wiley   +1 more source

Alterations in Biochemical Characteristics, Flavor, and Microbial Community During the Storage of Suancai. [PDF]

Foods
Xie X, Li Z, Liu H, Suo H, Zalán Z, Song J, Zhang Y.   +6 more
europepmc   +1 more source

Effects of Common Food Additives Kappa‐, Iota‐ and Lambda‐Carrageenans on Intestinal Epithelial Cell Activation and Barrier Disruption

Clinical &Experimental Allergy, EarlyView.
Carrageenans, widely used food additives, disrupted intestinal epithelial integrity in a gut‐on‐a‐chip model. All types (κ‐, ɩ‐, λ‐) induced cytotoxicity, inflammation and tight junction (TJ) disruption, triggering TNF‐mediated immune responses. λ‐Carrageenan had the most severe effects, supporting the Epithelial Barrier Theory linking food additives ...
Na Sun, Yagiz Pat, Huseyn Babayev, Sena Ardicli, Ismail Ogulur, Xianting Bu, Manru Li, Shuqi Jia, Beate Rückert, Raja Dhir, Kari C. Nadeau, Mubeccel Akdis, Cezmi A. Akdis, Duygu Yazici   +13 more
wiley   +1 more source

Application of Microorganisms for the Valorization of Side-Products of Rapeseed De-Oiling. [PDF]

Biomolecules
Binczarski MJ, Zuberek J, Fraczyk J, Kolesinska B, Radojčin M, Pavkov I, Wiktorowska-Sowa E, Piotrowski J, Kaminski ZJ, Witonska IA.   +9 more
europepmc   +1 more source

Volatiles from endangered Braya longii (Brassicales: Brassicaceae) influence oviposition choice by Plutella xylostella (Lepidoptera: Plutellidae). [PDF]

Environ Entomol
Hillier NK, Hermanutz L.
europepmc   +1 more source

Watercress (<i>Nasturtium officinale</i>) as a Functional Food for Non-Communicable Diseases Prevention and Management: A Narrative Review. [PDF]

Life (Basel)
Maluwa C, Zinan'dala B, Chuljerm H, Parklak W, Kulprachakarn K.   +4 more
europepmc   +1 more source

Nature-Inspired Pathogen and Cancer Protein Covalent Inhibitors: From Plants and Other Natural Sources to Drug Development. [PDF]

Pathogens
Roviello GN.
europepmc   +1 more source

TRP Channels from Sensory Coding to Physiology. [PDF]

Metabolites
Atif M, Lee Y.
europepmc   +1 more source