Results 121 to 130 of about 12,339 (203)

A clinical prediction model for central venous catheter-associated bloodstream infections: derivation and validation from the MIMIC-IV cohort

European Journal of Medical Research
Background Central venous catheter-associated bloodstream infections (CVC–BSIs) significantly affect clinical outcomes in critically ill patients. Existing risk prediction models lack comprehensive integration of early clinical indicators.
Bo Song, Guanjun Jiang, Yujia Liu, Dongsheng Cheng   +3 more
doaj   +1 more source

Investigation of the Effects of Perfluorooctane Sulfonic Acid (PFOS) and Perfluorooctanoic Acid (PFOA) Exposure on Interleukin‐17 Signalling and Poly(I:C)‐Induced Lung Inflammation in BALB/c Mice

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 2, August 2026.
ABSTRACT The aim of this study was to investigate the effects of co‐exposure to perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) on the IL‐17‐related immune responses and the Poly(I:C)‐induced lung inflammation. A total of 66 adult male BALB/c mice were divided into 11 groups, including controls, dose groups receiving PFOS+PFOA (1,
Eda Nur İnkaya, Seçil Karahisar Turan, Nurhayat Barlas   +2 more
wiley   +1 more source

Gβγ subunit activation of KV7 and BKCa channels underlies calcitonin gene‐related peptide vasorelaxation in myogenic rat coronary resistance arteries

British Journal of Pharmacology, Volume 183, Issue 16, Page 5018-5032, August 2026.
Abstract Background and Purpose CGRP is a potent, clinically relevant coronary vasodilator known to play a role in cardioprotection. Here, we investigated the precise intracellular signalling pathways leading to vasodilation in small coronary arteries.
Lucy A. Donovan, JinHeng Lin, Milind Khashu, Christopher J. Garland, Kim A. Dora   +4 more
wiley   +1 more source

Analytical and Clinical Performance of the Atellica HEMA 580 Haematology Analyzer: A Comparison With the ADVIA 2120i

International Journal of Laboratory Hematology, Volume 48, Issue 4, Page 784-794, August 2026.
ABSTRACT Introduction The Atellica HEMA 580 is a novel haematology analyser providing eight‐part leukocyte differential and optical platelet (PLT) counting. We compared its analytical and clinical performance with that of the ADVIA 2120i. Methods A total of 796 residual whole blood specimens were analysed.
Hyeongyu Lee, Jooyoung Cho, Gilsung Yoo, Juwon Kim   +3 more
wiley   +1 more source

Determining the Maximum Tolerable Concentration of Ropivacaine to Maintain Sensation of the Nerve Root in Percutaneous Endoscopic Transforaminal Lumbar Discectomy: Can Epidural Anaesthesia Achieve Pain-Tactile Separation Block to Avoid Nerve Injury?

Drug Design, Development and Therapy
Bingwei Hu,1,* Xianhui Kang,2,* Cheng Zhou,1 Jie Zhou,1 Weixing Xu,3 Weiguo Ding,3 Zhiying Feng,4 Hongwei Wang1 1Department of Anaesthesiology, Tongde Hospital of Zhejiang Province, Hangzhou, People’s Republic of China; 2Department of ...
Hu B, Kang X, Zhou C, Zhou J, Xu W, Ding W, Feng Z, Wang H   +7 more
doaj  

Altered Skeletal Muscle Phosphate Metabolism After Muscle Damage Is Associated With Elevated Effort Perception During Exercise in Humans

Scandinavian Journal of Medicine &Science in Sports, Volume 36, Issue 8, August 2026.
ABSTRACT It remains unclear why exercising damaged muscles is perceived as disproportionately more effortful. Given the known role of inorganic phosphate (Pi) in fatigue and afferent sensory signaling, we tested whether muscle damage disrupts phosphate metabolism and whether this is associated with heightened ratings of perceived exertion (RPE ...
Jamie Stewart McPhee, Aneurin James Kennerley, Jean‐Christophe Lagacé, James McStravick, Susan Pinner, Fabio Zambolin   +5 more
wiley   +1 more source

Locked plate versus modified clamp‐rod internal fixation for feline corpus ilium fractures: A comparative clinical study

Veterinary Surgery, Volume 55, Issue 6, Page 1133-1142, August 2026.
Abstract Objective To evaluate the applicability and clinical effectiveness of a modified clamp‐rod internal fixation (M‐CRIF) system compared with conventional locking plate osteosynthesis in the treatment of feline corpus ilium fractures. Study design Prospective, controlled clinical study.
Nahit Saylak, Sadık Yayla, Semih Altan, Berna Ersöz‐Kanay, Emine Çatalkaya   +4 more
wiley   +1 more source

Binary Classifier Calibration using an Ensemble of Near Isotonic Regression Models. [PDF]

Proc IEEE Int Conf Data Min, 2016
Naeini MP, Cooper GF.
europepmc   +1 more source

Isotonic Regression Based-Method in Quantitative High-Throughput Screenings for Genotoxicity. [PDF]

Dose Response, 2015
Fujii Y, Narita T, Tice RR, Takeda S, Yamada R.   +4 more
europepmc   +1 more source

COMBINING ISOTONIC REGRESSION AND EM ALGORITHM TO PREDICT GENETIC RISK UNDER MONOTONICITY CONSTRAINT. [PDF]

Ann Appl Stat, 2014
Qin J, Garcia TP, Ma Y, Tang MX, Marder K, Wang Y.   +5 more
europepmc   +1 more source