Results 131 to 140 of about 27,457 (208)

Chromaffin Versus Platelet Granules: What We Have Learned From Chromaffin Cells for Human Studies

open access: yesJournal of Neurochemistry, Volume 170, Issue 5, May 2026.
Chromaffin cells and platelets both utilize exocytosis to release biogenic amines stored within large dense‐core vesicles—specifically chromaffin granules (epinephrine) and δ‐granules (serotonin). While the chromaffin cell is the foundational model for studying the secretory pathway, platelets offer a highly accessible human cell source for clinical ...
Ricardo Borges
wiley   +1 more source

PostForecasts.jl: A Julia package for probabilistic forecasting by postprocessing point predictions

open access: yesSoftwareX
Postprocessing of point predictions is a relatively simple and efficient way to compute probabilistic forecasts, which are the basis of uncertainty assessment for decision support and risk management.
Arkadiusz Lipiecki, Rafał Weron
doaj   +1 more source

Tensor Changepoint Detection and Eigenbootstrap

open access: yesJournal of Time Series Analysis, Volume 47, Issue 3, Page 557-578, May 2026.
ABSTRACT Tensor data consisting of multivariate outcomes over the items and across the subjects with longitudinal and cross‐sectional dependence are considered. A completely distribution‐free and tweaking‐parameter‐free detection procedure for changepoints at different locations is designed, which does not require training data.
Michal Pešta   +2 more
wiley   +1 more source

Structural Genomic Variation and Its Potential Role in Deer Speciation

open access: yesMolecular Ecology, Volume 35, Issue 9, May 2026.
ABSTRACT Speciation is a key driver of biodiversity and understanding its genomic underpinnings can be important for predicting and managing biodiversity. Structural variants (SVs) are large‐scale (> 50 bp) changes in the genome and have been implicated in adaptive divergence and reproductive isolation. We investigated the role of SVs in the speciation
Faezeh Azimi Chetabi, Aaron Shafer
wiley   +1 more source

Weighted L∞ isotonic regression

open access: yesJournal of Computer and System Sciences, 2018
Abstract Algorithms are given for determining weighted L ∞ isotonic regressions satisfying order constraints given by a directed acyclic graph with n vertices and m edges. An Θ ( m log ⁡ n ) algorithm is given, but it uses parametric search, so a practical approach is introduced, based on calculating prefix solutions.
openaire   +2 more sources

Uncertainty Calibration in Molecular Machine Learning: Comparing Evidential and Ensemble Approaches

open access: yesChemistry – A European Journal, Volume 32, Issue 15, 22 April 2026.
Raw uncertainty estimates from deep evidential regression and deep ensembles are systematically miscalibrated. Post hoc calibration aligns predicted uncertainty with true errors, improving reliability and enabling efficient active learning and reducing computational cost while preserving predictive accuracy.
Bidhan Chandra Garain   +3 more
wiley   +1 more source

Radioiodination of Two Carborane‐Based Dual Cyclooxygenase‐2/5‐Lipoxygenase Inhibitors and Their In Vitro and In Vivo Evaluation

open access: yesChemBioChem, Volume 27, Issue 7, 14 April 2026.
Two dicarbadodecaborane(12)‐based dual cyclooxygenase‐2/5‐lipoxygenase (COX‐2/5‐LO) inhibitors were 123I‐labeled. Refinement of labeling and formulation conditions and extensive in vitro characterization are presented. Cell uptake studies in COX‐2‐ and 5‐LO‐overexpressing cell lines showed COX‐2‐independent and partly 5‐LO‐dependent uptake.
Jonas Schädlich   +11 more
wiley   +1 more source

Determining the Maximum Tolerable Concentration of Ropivacaine to Maintain Sensation of the Nerve Root in Percutaneous Endoscopic Transforaminal Lumbar Discectomy: Can Epidural Anaesthesia Achieve Pain-Tactile Separation Block to Avoid Nerve Injury?

open access: yesDrug Design, Development and Therapy
Bingwei Hu,1,* Xianhui Kang,2,* Cheng Zhou,1 Jie Zhou,1 Weixing Xu,3 Weiguo Ding,3 Zhiying Feng,4 Hongwei Wang1 1Department of Anaesthesiology, Tongde Hospital of Zhejiang Province, Hangzhou, People’s Republic of China; 2Department of ...
Hu B   +7 more
doaj  

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