Results 201 to 210 of about 188,123 (308)

Comparison of Tissue Preparations to Identify and Phenotype T Cells in Human Colorectal Tumor Tissue

Cytometry Part A, EarlyView.
ABSTRACT Archived patient samples (e.g., formalin‐fixed paraffin embedded (FFPE) tissue blocks, cryoembedded tissue blocks, and frozen whole tissue samples) are a source of immune information for which corresponding patient data is often collected.
Justin F. Tirados, Sonya Fenton, Helen M. McGuire, Joanna M. Roberts, Kirsten A. Ward‐Hartstonge, Roslyn A. Kemp   +5 more
wiley   +1 more source

Regulatory T cells sabotage anti-tumor γδ T cells by creating IL-2-deficient environments. [PDF]

J Exp Med
Blanco-Domínguez R, Vaz-Pinto AM, Barros L, Lopes N, Henriques-Alves B, Carreira M, Labão-Almeida C, Ribot JC, Bernardes GJL, Silva-Santos B, Mensurado S.   +10 more
europepmc   +1 more source

Establishment of pediatric reference ranges for circulating naïve and memory T and B cell subsets guided by the human immunophenotyping consortium standardization initiative: A large, single center U.S. experience

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Our knowledge of the immune system continues to expand at a rapid pace, and this coupled with technological advances now enables us to interrogate both the breadth and the depth of the immune response at levels without precedent. This has also facilitated rapidly integrating some of this carefully vetted knowledge into clinical practice ...
Aaruni Khanolkar, Aisha Ahmed
wiley   +1 more source

A MICA/B GAALIE-mutant antibody elicits potent natural killer cell-driven immunity in solid and hematologic malignancy models. [PDF]

Cell Rep Med
Pimenta R, Maurer S, Zhong X, Taciane da Silva Bortoleti B, Quasem S, Ribeiro de Lima Brandão L, Marcellino B, Dutta A, Arriaga JM, Mascarenhas J, Ferrari de Andrade L.   +10 more
europepmc   +1 more source

CD8+ T‐cells, CD86+ macrophages and TNF‐α signalling pathways are correlated with fetlock osteoarthritis in racehorses

Equine Veterinary Journal, EarlyView.
Abstract Background There is emerging evidence for the role of the immune system in osteoarthritis (OA) pathophysiology; however, little is known about how immune cells and the synovial transcriptome are altered in naturally occurring equine OA. Objectives To evaluate synovial fluid (SF) and synovial membrane (SM) immune cell populations and the SM ...
E. J. Secor, E. N. Chow, M. Thomas, L. Johnson, A. Siefert, B. Wagner, J. B. Engiles, H. L. Reesink   +7 more
wiley   +1 more source

B7-H3 (CD276) as Target for T Cell-Based Bispecific Antibody Therapy of Penile Cancer. [PDF]

Immunotargets Ther
Kielbik A, Bahlinger V, Schürch CM, Barcena ML, Vakhrusheva O, Thomas A, Tsaur I, Heitmann JS, Salih HR, Hagelstein I.   +9 more
europepmc   +1 more source

CCL26‐Mediated Modulation of Endothelial Secretome by Hypoxia‐Induced Tumor‐Derived Exosomes Enhances Metastatic Progression in Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Background Tumor cells adapt to hypoxia by releasing hiTDExs enriched with bioactive molecules that modulate endothelial behavior and promote tumor progression. This study aimed to characterize how hypoxia‐induced HNSCC exosomes reshape the endothelial secretome and contribute to metastatic potential.
Ozel Capik, Sevil Tekman, Betul Gundogdu, Ahsen Kilic, Rumeysa Polat, Omer Aydin, Omer Faruk Karatas   +6 more
wiley   +1 more source

Targeting CRTC2 reverses <i>STK11</i> mutant NSCLC tumor resistance to immunotherapy. [PDF]

Proc Natl Acad Sci U S A
Robay D, Ackermann O, Laborde L, Shi X, Oreglia F, Stump R, Ciaghi S, Galli GG, Holzer L, Villemin L, Wagner J, Wu J, Lee LH, Bossen C, Mourikis TP, Gabriel M, Ruddy D, Yu H, Johannessen C, Ferretti S, Costa C.   +20 more
europepmc   +1 more source

Isotype Switching [PDF]

, 2008
openaire   +1 more source

Modified Anti-PstS1 Bi-specific antibodies unlock potent protection against tuberculosis. [PDF]

PLoS Pathog
Akanksha, Bouzeyen R, Watson A, Wiseglass G, Sithole N, Abramovitz L, Ben-Shalom N, Rubinstein R, Javid B, Freund NT.   +9 more
europepmc   +1 more source