Results 221 to 230 of about 197,507 (284)

Lymph node fine-tuning FcγR signaling boosts anti-PD-1 therapy. [PDF]

J Immunother Cancer
Guérin MV, Ruggiu M, Feldmann LC, Corre B, Ombredanne P, Iannascoli B, Garcia Z, Lemaître F, Macdonald L, Guermonprez P, Grandjean CL, Bruhns P, Bousso P.   +12 more
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Development of [111In]In-CHX-A″-DTPA-αCD68 for ImmunoSPECT to Image Murine Macrophages. [PDF]

Mol Pharm
Strong AE, Belitzky E, Vaughn Embs A, Katz S, Cavaliere A, Djureinovic D, Roohani B, Liu M, Rothlin C, Leavenworth JW, Jilaveanu L, Kluger HM, Marquez-Nostra B.   +12 more
europepmc   +1 more source

Tocilizumab but not Siltuximab prevents systemic inflammation in a humanized mouse model. [PDF]

Front Immunol
Zhang L, Wax J, Goldmann T, Mehrpouyan A, Müller A, Petersen F, Riemekasten G, Yu X.   +7 more
europepmc   +1 more source

Generation and characterization of an anti ITGB4 monoclonal antibody that blocks Zika virus entry. [PDF]

Front Immunol
Han X, Li W, Yang S, Gong Y, Shen J, Song L, Wan F, Wang G, Cong H.   +8 more
europepmc   +1 more source

On holotypes and isotypes

, 2006
openaire   +2 more sources

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Isotype Determination of Antibodies

Current Protocols in Immunology, 1992
AbstractOn identifying a new monoclonal antibody, or in characterizing antibodies in sera evoked by disease or immunization, it is particularly informative to determine the serological class of the antibodies. The serological class of the protein is determined by the structure of the antibody constant region.
Peter, Hornbeck, Thomas A, Fleisher, Nicholas M, Papadopoulos   +2 more
openaire   +4 more sources

Bases for an isotypic network

Molecular Immunology, 1986
In 1974 Jerne proposed that the immune system functions as a network of interacting antibody combining sites (paratopes); each paratope reacts with determinants (idiotopes) borne by V regions of immunoglobulins (Ig)* and expresses idiotopes which are recognized by paratopes of other Ig (Jerne, 1974).
W H, Fridman, M, Daëron, S, Amigorena, C, Rabourdin-Combe, C, Neauport-Sautes   +4 more
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Regulation of isotype switching

Current Opinion in Immunology, 1992
In the past year, our understanding of the mechanisms that regulate isotype switching has significantly progressed. Activation of germ line transcription by isotype-specific cytokines is emerging as a crucial mechanism for increasing the accessibility of a particular switch region, and targeting switch recombination.
D, Vercelli, R S, Geha
openaire   +2 more sources