Results 1 to 10 of about 20,447 (254)
Immunoglobulin Isotypes in Atlantic Salmon, Salmo Salar [PDF]
Biomolecules, 2015 There are three major immunoglobulin (Ig) isotypes in salmonid fish: IgM, IgD and IgT, defined by the heavy chains μ, δ and τ, respectively. As a result of whole genome duplication in the ancestor of the salmonid fish family, Atlantic salmon (Salmo salar)
Ivar Hordvik, Hordvik Ivar
exaly +11 more sources
Evolution of the Immunoglobulin Isotypes—Variations of Biophysical Properties among Animal Classes [PDF]
Biomolecules, 2023 The adaptive immune system arose around 500 million years ago in jawed fish, and, since then, it has mediated the immune defense against pathogens in all vertebrates.
Nancy D Pomarici +2 more
exaly +5 more sources
B cells defined by immunoglobulin isotypes. [PDF]
Clin Exp Immunol, 2022 SummaryThe ability of B cells to generate antibodies and provide long-lived protective immunity is the cornerstone of vaccination and has contributed to the success of modern medicine. The nine different antibody subclasses produced by humans have effector functions that differ according to antigen type and route of exposure.
James LK.
europepmc +4 more sources
Intratumoral immunoglobulin isotypes predict survival in lung adenocarcinoma subtypes [PDF]
Journal for ImmunoTherapy of Cancer, 2019 Background The role of tumor-infiltrating B-cells (TIBs) and intratumorally-produced antibodies in cancer-immunity interactions essentially remains terra incognita.
O. I. Isaeva +6 more
doaj +2 more sources
Kappa free light chain index in CSF diagnostics: the impact of different immunoglobulin isotypes [PDF]
Frontiers in ImmunologyBackgroundThe kappa free light chain (κ-FLC) index is a sensitive marker of intrathecal immunoglobulin (Ig) synthesis and is increasingly used in cerebrospinal fluid (CSF) analysis of patients with suspected multiple sclerosis (MS).
Martin Schmidauer +12 more
doaj +2 more sources
The potential to improve Lyme disease diagnostics through quantification of immunoglobulin class switching patterns [PDF]
Journal of Clinical MicrobiologyN. Nair, A. Marques , E. J. Horn, G. Brown et al., J Clin Microbiol 63:e0034725, 2025, https://doi.org/10.1128/jcm.00347-25 present data to demonstrate that infection by Borrelia burgdorferi, the primary causative agent of Lyme disease in the USA, leads ...
Anna M. Schotthoefer
doaj +2 more sources
Aging and immunoglobulin isotype patterns in oral tolerance [PDF]
Brazilian Journal of Medical and Biological Research, 1998 In the present review we address oral tolerance as an important biological phenomenon and discuss how it is affected by aging. Other factors such as frequency of feeding and previous digestion of the antigen also seem to influence the establishment of ...
A.M.C. Faria +8 more
doaj +5 more sources
Immunoglobulin isotypes and IgG subclasses in recurrent infections
The Turkish Journal of Pediatrics, 1997 The frequency of major immunoglobulin isotype and IgG subclass deficiencies among 74 children aged six months to 14 years with recurrent infections was studied.
Y Coşkun, Z Bayraktaroğlu
doaj +2 more sources
Detection of immunoglobulin isotypes from dried blood spots [PDF]
Journal of Immunological Methods, 2014 Charlotte Druschel +2 more
exaly +2 more sources
Frontiers in Oncology, 2023 The analysis of the immunogenetic background of multiple myeloma (MM) has proven key to understanding disease ontogeny. However, limited information is available regarding the immunoglobulin (IG) gene repertoire in MM cases carrying different heavy chain
Glykeria Gkoliou +20 more
doaj +1 more source