Results 21 to 30 of about 20,447 (254)

The immunopathology of human schistosomiasis-III: immunoglobulin isotype profiles and response to praziquantel

Memorias do Instituto Oswaldo Cruz, 1996
Immunoglobulin (Ig) isotype (IgG, IgG1, IgG2, IgG3, IgG4, IgM, IgD and IgE) levels were investigated, both pre- and post-treatment with praziquantel (PZQ), in 43 adults and children chronically infected with Schistosoma mansoni , by means of a two-site ...
Romelia M Ramírez, Evelia Ceballos, Belkisyolé Alarcón de Noya, Oscar Noya, Nicolás Bianco   +4 more
doaj   +1 more source

Immunoglobulin genes and diversity: what we have learned from domestic animals

Journal of Animal Science and Biotechnology, 2012
This review focuses on the diversity of immunoglobulin (Ig) genes and Ig isotypes that are expressed in domestic animals. Four livestock species—cattle, sheep, pigs, and horses—express a full range of Ig heavy chains (IgHs), including μ, δ, γ, ϵ, and α ...
Sun Yi, Liu Zhancai, Ren Liming, Wei Zhiguo, Wang Ping, Li Ning, Zhao Yaofeng   +6 more
doaj   +1 more source

Pregnancy mediated improvement of rheumatoid arthritis

Swiss Medical Weekly, 2012
QUESTION UNDER STUDY: To investigate pregnancy related changes of rheumatoid factor (RF) isotypes and anti-citrullinated protein antibodies (ACPA) and their association with disease activity and therapy in patients with rheumatoid arthritis.
Frauke Förger, Inka Vallbracht, Klaus Helmke, Peter Matthias Villiger, Monika Ostensen   +4 more
doaj   +1 more source

Exceptionally long CDR3H are not isotype restricted in bovine immunoglobulins. [PDF]

PLoS ONE, 2013
Exceptionally long third complementarity determining regions of the heavy chain (CDR3H) were previously described as a specificity of bovine IgG and IgM immunoglobulins.
Stefanie Walther, Claus-Peter Czerny, Ulrike S Diesterbeck   +2 more
doaj   +1 more source

Vaginal microbiome dysbiosis and sexually transmitted infections correlate with concentrations of immunoglobulin isotypes in human cervicovaginal mucus: insights into HIV-1 transmission. [PDF]

Front Immunol
Introduction: Little is known about the relationship between antibody isotype in cervicovaginal mucus (CVM) and the local microenvironment and how this impacts HIV-1 transmission at the female genital mucosa.
Akiso MM, Abook I, Mureithi MW, Kombo J, Koi P, Musando J, Chirchir RJ, McRaven MD, Carias AM, Joseph S, Anzala O, Hope TJ.   +11 more
europepmc   +2 more sources

Integrative transcriptome and chromatin landscape analysis reveals distinct epigenetic regulations in human memory B cells

Nature Communications, 2020
Human memory B cells differentiate from naïve B cells and can express different immunoglobulin (Ig) isotypes resulted from class-switch recombination.
Justin B. Moroney, Anusha Vasudev, Alexander Pertsemlidis, Hong Zan, Paolo Casali   +4 more
doaj   +1 more source

Comparable Long-Term Rabies Immunity in Foxes after IntraMuscular and Oral Application Using a Third-Generation Oral Rabies Virus Vaccine

Vaccines, 2021
The live genetically-engineered oral rabies virus (RABV) variant SPBN GASGAS induces long-lasting immunity in foxes and protection against challenge with an otherwise lethal dose of RABV field strains both after experimental oral and parenteral routes of
Verena te Kamp, Virginia Friedrichs, Conrad M. Freuling, Ad Vos, Madlin Potratz, Antonia Klein, Luca M. Zaeck, Elisa Eggerbauer, Peter Schuster, Christian Kaiser, Steffen Ortmann, Antje Kretzschmar, Katharina Bobe, Michael R. Knittler, Anca Dorhoi, Stefan Finke, Thomas Müller   +16 more
doaj   +1 more source

Antigen-specific influence of GM/KM allotypes on IgG isotypes and association of GM allotypes with susceptibility to Plasmodium falciparum malaria [PDF]

, 2009
Background Plasmodium falciparum malaria is a complex disease in which genetic and environmental factors influence susceptibility. IgG isotypes are in part genetically controlled, and GM/KM allotypes are believed to be involved in this control.
Thor G Theander, Troye-Blomberg, Marita,, Marita Troye-Blomberg, ElGhazali, Gehad, ElGhazali Gehad, Janardan P Pandey, Giha, Hayder A., Pandey, Janardan P, Giha Hayder A, Iriemenam, Nnaemeka C., Nasr, Amre, Gehad ElGhazali, David Arnot, Giha, Hayder A, Nasr, Amre,, Troye-Blomberg, Marita, Theander, Thor G., Pandey, Janardan P., Berzins, Klavs, Berzins Klavs, Berzins, Klavs,, Hayder A Giha, Nnaemeka C Iriemenam, Theander, Thor G, Theander Thor G, Iriemenam, Nnaemeka C, Troye-Blomberg Marita, Nasr Amre, Klavs Berzins, Iriemenam Nnaemeka C, Arnot, David, Amre Nasr, Arnot David, Pandey Janardan P, Iriemenam, Nnaemeka C.,   +34 more
core   +1 more source

The synergistic effects of the constant region and variable heavy chain families of multimeric immunoglobulin M on its interaction with Fc-mu receptor and antigen

Exploration of Immunology, 2022
Aim: As the primary response antibody with increasing use as a therapeutic immunoglobulin (Ig) format, IgM is also the largest antibody structure among the five major human isotypes. Spontaneously formed pentamers and hexamers of IgM have avidity effects
Wei-Li Ling, Samuel Ken-En Gan
doaj   +1 more source

Revisiting the Impact of Immunoglobulin Isotypes in Multiple Myeloma

Blood, 2020
Background Multiple Myeloma (MM) is a malignancy of terminally differentiated B lymphocytes (plasma cells, PCs) characterized by secretion of immunoglobulins and/or light chains (LCs). Association of immunoglobulin isotypes with survival in the context of contemporary therapies and accounting for modern prognostic factors has not been ...
Susan Bal, Smith Giri, Kelly N. Godby, Luciano J. Costa   +3 more
openaire   +2 more sources