Results 31 to 40 of about 478,815 (317)
Aim: As the primary response antibody with increasing use as a therapeutic immunoglobulin (Ig) format, IgM is also the largest antibody structure among the five major human isotypes. Spontaneously formed pentamers and hexamers of IgM have avidity effects
Wei-Li Ling, Samuel Ken-En Gan
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Potential immunological markers for diagnosis and therapeutic assessment of toxocariasis
In human toxocariasis, there are few approaches using immunological markers for diagnosis and therapeutic assessment. An immunoblot (IB) assay using excretory-secretory Toxocara canis antigen was standardized for monitoring IgG, IgE and IgA antibodies in
Guita Rubinsky-Elefant +4 more
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Three IgH isotypes, IgM, IgA and IgY are expressed in Gentoo penguin and zebra finch. [PDF]
Previous studies on a limited number of birds suggested that the IgD-encoding gene was absent in birds. However, one of our recent studies showed that the gene was definitely expressed in the ostrich and emu.
Binyue Han +5 more
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Interactions between Gold Nanoparticles and Immunoglobulin Isotypes [PDF]
Gold Nanoparticles have piqued interest for use in a wide range of diagnostic and therapeutic applications including biosensors, assays, vaccine development, drug delivery, and photothermal therapy.
Hassan, Rick
core
Characterization of mixed lymphocyte reaction blocking antibodies (MLR-Bf) in human pregnancy
Background It is known that during normal pregnancy and after immunotherapy blocking antibodies are developed, these antibodies inhibit mixed lymphocyte reaction and are also anti-mitogenic in nature.
Agrawal Suraksha +2 more
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Influence of immunoglobulin isotype on therapeutic antibody function [PDF]
AbstractMonoclonal antibody (mAb) therapeutics are revolutionizing cancer treatment; however, not all tumors respond, and agent optimization is essential to improve outcome. It has become clear over recent years that isotype choice is vital to therapeutic success with agents that work through different mechanisms, direct tumor targeting, agonistic ...
Beers, S., Glennie, M., White, A.
openaire +3 more sources
Antibodies and their receptors: different potential roles in mucosal defence
Over recent years it has become increasingly apparent that mucosal antibodies are not only restricted to the IgM and IgA isotypes, but that also other isotypes and particularly IgG can be found in significant quantities at some mucosal surfaces, such as ...
Rachel eHorton, Gestur eVidarsson
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Nematode infections may induce immune-modulatory effects and influence host-immune responses to other pathogens. The aim of the study was to investigate whether a mixed nematode-infection influences non-specific and vaccine-induced humoral immunity ...
Gürbüz Daş +6 more
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Long-Range Control of Class Switch Recombination by Transcriptional Regulatory Elements
Immunoglobulin class switch recombination (CSR) plays a crucial role in adaptive immune responses through a change of the effector functions of antibodies and is triggered by T-cell-dependent as well as T-cell-independent antigens.
Audrey Dauba, Ahmed Amine Khamlichi
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Opsonization of Staphylococcus aureus by bovine immunoglobulin isotypes.
The ability of specific bovine Ig isotypes to enhance phagocytosis of Staphylococcus aureus by polymorphonuclear neutrophils was studied. Polymorphonuclear neutrophils were isolated from the blood of 14 lactating Holstein cows. Antibodies against S. aureus M10 were produced by two Holstein cows immunized via intramuscular injections and injections in ...
A. Guidry, L. Berning, C. Hambleton
semanticscholar +3 more sources

