Results 31 to 40 of about 20,447 (254)

Acquisition of antibody isotypes against Plasmodium falciparum blood stage antigens in a birth cohort. [PDF]

open access: yes, 2010
Information on the period during which infants lose their maternally derived antibodies to malaria and begin to acquire naturally their own immune responses against parasite antigens is crucial for understanding when malaria vaccines may be best ...
Duah, NO   +7 more
core   +1 more source

Potential immunological markers for diagnosis and therapeutic assessment of toxocariasis

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2011
In human toxocariasis, there are few approaches using immunological markers for diagnosis and therapeutic assessment. An immunoblot (IB) assay using excretory-secretory Toxocara canis antigen was standardized for monitoring IgG, IgE and IgA antibodies in
Guita Rubinsky-Elefant   +4 more
doaj   +1 more source

Influence of immunoglobulin isotype on therapeutic antibody function [PDF]

open access: yesBlood, 2016
AbstractMonoclonal antibody (mAb) therapeutics are revolutionizing cancer treatment; however, not all tumors respond, and agent optimization is essential to improve outcome. It has become clear over recent years that isotype choice is vital to therapeutic success with agents that work through different mechanisms, direct tumor targeting, agonistic ...
Beers, S., Glennie, M., White, A.
openaire   +3 more sources

Heatmap representing the differences in total immunoglobulin and immunoglobulin heavy chain relative abundance between neonates, foals, and adult horses.

open access: yes, 2023
Yellow tones indicate a significant lower relative abundance. Groups are shown in columns, the rows represent the immunoglobulin isotypes.
Adina R. Bujold (16940729)   +6 more
core   +1 more source

Antibodies and their receptors: different potential roles in mucosal defence

open access: yesFrontiers in Immunology, 2013
Over recent years it has become increasingly apparent that mucosal antibodies are not only restricted to the IgM and IgA isotypes, but that also other isotypes and particularly IgG can be found in significant quantities at some mucosal surfaces, such as ...
Rachel eHorton, Gestur eVidarsson
doaj   +1 more source

Characterization of mixed lymphocyte reaction blocking antibodies (MLR-Bf) in human pregnancy

open access: yesBMC Pregnancy and Childbirth, 2003
Background It is known that during normal pregnancy and after immunotherapy blocking antibodies are developed, these antibodies inhibit mixed lymphocyte reaction and are also anti-mitogenic in nature.
Agrawal Suraksha   +2 more
doaj   +1 more source

Impact of Nematode Infections on Non-specific and Vaccine-Induced Humoral Immunity in Dual-Purpose or Layer-Type Chicken Genotypes

open access: yesFrontiers in Veterinary Science, 2021
Nematode infections may induce immune-modulatory effects and influence host-immune responses to other pathogens. The aim of the study was to investigate whether a mixed nematode-infection influences non-specific and vaccine-induced humoral immunity ...
Gürbüz Daş   +6 more
doaj   +1 more source

ІMMUNOGLOBULIN ISOTYPES AND BLOOD MONOCYTE SUBPOPULATIONS IN COVID-19 FEMALE PATIENTS WITH DIFFERENT DISEASE SEVERITY [PDF]

open access: yesBiotechnologia Acta, 2022
COVID-19 disease, an acute respiratory infection caused by the SARS-CoV-2 virus, manifests itself in various severity forms - mild, moderate and severe, caused by the reactions of the patient's immune response. Aim.
K. Rebenko, B. Donskoy, L. Stamboli
doaj   +1 more source

Immunopathology of rabies infection in mice selected for high or low acute inflammatory reaction

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2007
Rabies is a severe and lethal disease that produces a slight inflammatory response during the infection process. We analyzed the immunopathological mechanisms that occur in the central nervous system (CNS) using mice genetically selected for maximal or ...
S. M. Achkar   +5 more
doaj   +1 more source

Long-Range Control of Class Switch Recombination by Transcriptional Regulatory Elements

open access: yesFrontiers in Immunology, 2021
Immunoglobulin class switch recombination (CSR) plays a crucial role in adaptive immune responses through a change of the effector functions of antibodies and is triggered by T-cell-dependent as well as T-cell-independent antigens.
Audrey Dauba, Ahmed Amine Khamlichi
doaj   +1 more source

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