Acquisition of antibody isotypes against Plasmodium falciparum blood stage antigens in a birth cohort. [PDF]
Information on the period during which infants lose their maternally derived antibodies to malaria and begin to acquire naturally their own immune responses against parasite antigens is crucial for understanding when malaria vaccines may be best ...
Duah, NO +7 more
core +1 more source
Potential immunological markers for diagnosis and therapeutic assessment of toxocariasis
In human toxocariasis, there are few approaches using immunological markers for diagnosis and therapeutic assessment. An immunoblot (IB) assay using excretory-secretory Toxocara canis antigen was standardized for monitoring IgG, IgE and IgA antibodies in
Guita Rubinsky-Elefant +4 more
doaj +1 more source
Influence of immunoglobulin isotype on therapeutic antibody function [PDF]
AbstractMonoclonal antibody (mAb) therapeutics are revolutionizing cancer treatment; however, not all tumors respond, and agent optimization is essential to improve outcome. It has become clear over recent years that isotype choice is vital to therapeutic success with agents that work through different mechanisms, direct tumor targeting, agonistic ...
Beers, S., Glennie, M., White, A.
openaire +3 more sources
Yellow tones indicate a significant lower relative abundance. Groups are shown in columns, the rows represent the immunoglobulin isotypes.
Adina R. Bujold (16940729) +6 more
core +1 more source
Antibodies and their receptors: different potential roles in mucosal defence
Over recent years it has become increasingly apparent that mucosal antibodies are not only restricted to the IgM and IgA isotypes, but that also other isotypes and particularly IgG can be found in significant quantities at some mucosal surfaces, such as ...
Rachel eHorton, Gestur eVidarsson
doaj +1 more source
Characterization of mixed lymphocyte reaction blocking antibodies (MLR-Bf) in human pregnancy
Background It is known that during normal pregnancy and after immunotherapy blocking antibodies are developed, these antibodies inhibit mixed lymphocyte reaction and are also anti-mitogenic in nature.
Agrawal Suraksha +2 more
doaj +1 more source
Nematode infections may induce immune-modulatory effects and influence host-immune responses to other pathogens. The aim of the study was to investigate whether a mixed nematode-infection influences non-specific and vaccine-induced humoral immunity ...
Gürbüz Daş +6 more
doaj +1 more source
ІMMUNOGLOBULIN ISOTYPES AND BLOOD MONOCYTE SUBPOPULATIONS IN COVID-19 FEMALE PATIENTS WITH DIFFERENT DISEASE SEVERITY [PDF]
COVID-19 disease, an acute respiratory infection caused by the SARS-CoV-2 virus, manifests itself in various severity forms - mild, moderate and severe, caused by the reactions of the patient's immune response. Aim.
K. Rebenko, B. Donskoy, L. Stamboli
doaj +1 more source
Immunopathology of rabies infection in mice selected for high or low acute inflammatory reaction
Rabies is a severe and lethal disease that produces a slight inflammatory response during the infection process. We analyzed the immunopathological mechanisms that occur in the central nervous system (CNS) using mice genetically selected for maximal or ...
S. M. Achkar +5 more
doaj +1 more source
Long-Range Control of Class Switch Recombination by Transcriptional Regulatory Elements
Immunoglobulin class switch recombination (CSR) plays a crucial role in adaptive immune responses through a change of the effector functions of antibodies and is triggered by T-cell-dependent as well as T-cell-independent antigens.
Audrey Dauba, Ahmed Amine Khamlichi
doaj +1 more source

