Results 31 to 40 of about 478,815 (317)

The synergistic effects of the constant region and variable heavy chain families of multimeric immunoglobulin M on its interaction with Fc-mu receptor and antigen

open access: yesExploration of Immunology, 2022
Aim: As the primary response antibody with increasing use as a therapeutic immunoglobulin (Ig) format, IgM is also the largest antibody structure among the five major human isotypes. Spontaneously formed pentamers and hexamers of IgM have avidity effects
Wei-Li Ling, Samuel Ken-En Gan
doaj   +1 more source

Potential immunological markers for diagnosis and therapeutic assessment of toxocariasis

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2011
In human toxocariasis, there are few approaches using immunological markers for diagnosis and therapeutic assessment. An immunoblot (IB) assay using excretory-secretory Toxocara canis antigen was standardized for monitoring IgG, IgE and IgA antibodies in
Guita Rubinsky-Elefant   +4 more
doaj   +1 more source

Three IgH isotypes, IgM, IgA and IgY are expressed in Gentoo penguin and zebra finch. [PDF]

open access: yesPLoS ONE, 2017
Previous studies on a limited number of birds suggested that the IgD-encoding gene was absent in birds. However, one of our recent studies showed that the gene was definitely expressed in the ostrich and emu.
Binyue Han   +5 more
doaj   +1 more source

Interactions between Gold Nanoparticles and Immunoglobulin Isotypes [PDF]

open access: yes, 2021
Gold Nanoparticles have piqued interest for use in a wide range of diagnostic and therapeutic applications including biosensors, assays, vaccine development, drug delivery, and photothermal therapy.
Hassan, Rick
core  

Characterization of mixed lymphocyte reaction blocking antibodies (MLR-Bf) in human pregnancy

open access: yesBMC Pregnancy and Childbirth, 2003
Background It is known that during normal pregnancy and after immunotherapy blocking antibodies are developed, these antibodies inhibit mixed lymphocyte reaction and are also anti-mitogenic in nature.
Agrawal Suraksha   +2 more
doaj   +1 more source

Influence of immunoglobulin isotype on therapeutic antibody function [PDF]

open access: yesBlood, 2016
AbstractMonoclonal antibody (mAb) therapeutics are revolutionizing cancer treatment; however, not all tumors respond, and agent optimization is essential to improve outcome. It has become clear over recent years that isotype choice is vital to therapeutic success with agents that work through different mechanisms, direct tumor targeting, agonistic ...
Beers, S., Glennie, M., White, A.
openaire   +3 more sources

Antibodies and their receptors: different potential roles in mucosal defence

open access: yesFrontiers in Immunology, 2013
Over recent years it has become increasingly apparent that mucosal antibodies are not only restricted to the IgM and IgA isotypes, but that also other isotypes and particularly IgG can be found in significant quantities at some mucosal surfaces, such as ...
Rachel eHorton, Gestur eVidarsson
doaj   +1 more source

Impact of Nematode Infections on Non-specific and Vaccine-Induced Humoral Immunity in Dual-Purpose or Layer-Type Chicken Genotypes

open access: yesFrontiers in Veterinary Science, 2021
Nematode infections may induce immune-modulatory effects and influence host-immune responses to other pathogens. The aim of the study was to investigate whether a mixed nematode-infection influences non-specific and vaccine-induced humoral immunity ...
Gürbüz Daş   +6 more
doaj   +1 more source

Long-Range Control of Class Switch Recombination by Transcriptional Regulatory Elements

open access: yesFrontiers in Immunology, 2021
Immunoglobulin class switch recombination (CSR) plays a crucial role in adaptive immune responses through a change of the effector functions of antibodies and is triggered by T-cell-dependent as well as T-cell-independent antigens.
Audrey Dauba, Ahmed Amine Khamlichi
doaj   +1 more source

Opsonization of Staphylococcus aureus by bovine immunoglobulin isotypes.

open access: yesJournal of Dairy Science, 1993
The ability of specific bovine Ig isotypes to enhance phagocytosis of Staphylococcus aureus by polymorphonuclear neutrophils was studied. Polymorphonuclear neutrophils were isolated from the blood of 14 lactating Holstein cows. Antibodies against S. aureus M10 were produced by two Holstein cows immunized via intramuscular injections and injections in ...
A. Guidry, L. Berning, C. Hambleton
semanticscholar   +3 more sources

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