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Evolution of isotype switching
Seminars in Immunology, 2004This review discusses evolution of the process of Ig heavy chain class switching, relating it to the first appearance of somatic hypermutation (SHM) of variable region genes. First, we discuss recent findings on the mechanism of class switch recombination (CSR) in mice and humans, and then review the mechanisms of expression of Ig heavy chain isotypes ...
Stavnezer, Janet, Amemiya, Chris T.
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Immunoglobulin Isotype Expression
1978Many different kinds of observations suggest that during development of the B cell line, individual V H genes determining the antibody specificity of an immunoglobulin molecule can be expressed with multiple C H genes. Thus each clone of B cells, defined by expression of a variable-region gene for the light and heavy chains of the immunoglobulin ...
J F, Kearney, E R, Abney
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Information Design Journal, 1981
Isotype has been a purely historical phenomenon for about ten years. It proposed a system for presenting information in visual form; but how can designers now learn from this work ? It is argued that Isotype cannot be fully articulated as method, and that it should be understood rather as approach.
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Isotype has been a purely historical phenomenon for about ten years. It proposed a system for presenting information in visual form; but how can designers now learn from this work ? It is argued that Isotype cannot be fully articulated as method, and that it should be understood rather as approach.
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TAXON, 1969
SummaryThe term isopleths is proposed as a general term for specimens bearing the same collector's or collection number. Examples are given of isopleths of holotypes which are not isotypes, i.e. which were not seen by the original author of the name in question.
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SummaryThe term isopleths is proposed as a general term for specimens bearing the same collector's or collection number. Examples are given of isopleths of holotypes which are not isotypes, i.e. which were not seen by the original author of the name in question.
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Juni : Magazin für Literatur und Kultur, 2019
Der Beitrag untersucht die politischen Implikationen von Otto Neuraths visueller ...
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Der Beitrag untersucht die politischen Implikationen von Otto Neuraths visueller ...
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Regional immunology, 1990
Within 6 hours after primary immunization the serum of mice contains a unique form of processed antigen which is complexed with immunoglobulin (Ig). These complexes are formed through the mediation of a T cell factor and markedly enhance in vivo the 7s antibody response.
S T, Lee +4 more
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Within 6 hours after primary immunization the serum of mice contains a unique form of processed antigen which is complexed with immunoglobulin (Ig). These complexes are formed through the mediation of a T cell factor and markedly enhance in vivo the 7s antibody response.
S T, Lee +4 more
openaire +1 more source
Comprehensive overview of autoantibody isotype and subclass distribution
Journal of Allergy and Clinical Immunology, 2022Mikhail Volkov
exaly