Results 31 to 40 of about 49,108 (308)

Monoclonal and polyclonal antibodies to chicken immunoglobulin isotypes specifically detect turkey immunoglobulin isotypes

, 1997
Turkey immunoglobulin (Ig) isotypes IgG and IgM were isolated from blood and IgA was isolated from bile. Isolation was accomplished by gel filtration of the ammonium sulphate cut on Sephacryl S-200.
Arnouts, S., Goddeeris, Bruno, Ducatelle, R., Haesebrouck, F., Davison, T.F., VanNerom, A., Kaspers, B.   +6 more
core   +2 more sources

Lack of correlation between rabies virus replication in the brain and antibody isotype profile in genetically modified mice

Journal of Venomous Animals and Toxins including Tropical Diseases, 2006
The relationship among the phenotypes resistance to infection, virus replication in the brain and isotype production was investigated in genetically modified High (H) or Low (L) antibody responder mouse lines.
C. A. Consales, C. A. Pereira, E. C. Passos, M. L. Carrieri, N. M. F. Galina, O. A. Sant'Anna   +5 more
doaj   +1 more source

Possible Roles of Specific Amino Acids in β-Tubulin Isotypes in the Growth and Maintenance of Neurons: Novel Insights From Cephalopod Mollusks

Frontiers in Molecular Neuroscience, 2022
Microtubules, are formed of the protein tubulin, which is a heterodimer of α- and β-tubulin subunits. Both α- and β-tubulin exist as numerous isotypes, differing in amino acid sequence and tissue distribution.
Richard F. Ludueña
doaj   +1 more source

Murine antibody isotypes and CDR sequence comparisons.

, 2018
Murine antibody isotypes and CDR sequence comparisons.
Fiona E. Scott (5566007), A. Munro Neville (354616), Benjamin Gloria (5566001), Andrew M. Scott (172529), Hong Li (20183), Manuel Zeitelhofer (150938), Bruno Catimel (2177790), Angelo Perani (5566004), Laura Allan (3765208), Ingrid Nilsson (157323), Xicong Liu (5565998), Carmel Murone (665264), Ulf Eriksson (157345)   +12 more
core   +1 more source

Isotype of the conquest

Information Design Journal, 2022
Abstract This article introduces the Codices of The School of Huejotzingo as early examples of data visualization from sixteenth-century colonial México. The glyphs in the Codices and the technique of repetition are used to represent quantities. A similar approach was introduced four hundred years later in 1930s Vienna that would become known as ...
openaire   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Reproducibility Assessment of Enzyme-Linked Immunosorbent Assays to Detect Anti-HPV16 L1-Specific IgG1, IgG3, IgA, and IgM Antibodies

Vaccines
Background/Objectives: Enzyme-linked immunosorbent assays (ELISAs) have been used to measure anti-human-papillomavirus (HPV) immunoglobulin IgG. The goal of this study was to evaluate the reproducibility of ELISAs measuring different HPV immunoglobulin ...
Ken Matsui, Heidi Anne Hempel, Gloriana Shelton, Rebecca Ocampo, Troy J. Kemp, Yuanji Pan, Ligia A. Pinto   +6 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Regulatory considerations in the design, development and quality of monoclonal antibodies and related products for the diagnosis and treatment of cancer

Frontiers in Oncology
Over 160 therapeutic and in vivo diagnostic monoclonal antibodies have been approved by the US FDA since the first monoclonal antibody, muromonab, was approved in 1986.
Marjorie A. Shapiro
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source