Results 11 to 20 of about 49,108 (308)
Tubulin isotypes – functional insights from model organisms [PDF]
, 2022 The microtubule cytoskeleton is assembled from the α- and β-tubulin subunits of the canonical tubulin heterodimer, which polymerizes into microtubules, and a small number of other family members, such as γ-tubulin, with specialized functions.
Nsamba, Emmanuel, Gupta, Mohan
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The Expression and Function of Tubulin Isotypes in Caenorhabditis elegans
Frontiers in Cell and Developmental Biology, 2022 Microtubules, made from the polymerization of the highly conserved α/β-tubulin heterodimers, serve as important components of the cytoskeleton in all eukaryotic cells.
Yu-Ming Lu, Chaogu Zheng
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IgE in the Pathogenesis of SLE: From Pathogenic Role to Therapeutic Target
Antibodies, 2020 Systemic lupus erythematosus (SLE) is a multifactorial chronic autoimmune disease, marked by the presence of autoantibodies to nuclear antigens belonging to different isotype classes.
Yasmine Lamri, Nicolas Charles
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Prevalence of anti- beta2GPI antibodies and their isotypes in patients with renal diseases and clinical suspicion of antiphospholipid syndrome [PDF]
Journal of Nephropathology, 2013 Background: Antiphospholipid antibodies (aPL) are autoantibodies that are associated with a clinical state of hypercoagulability and diverse clinical manifestations collectively known as antiphospholipid syndrome (APS).
Sabiha Anis, Ejaz Ahmed, Rana Muzaffar
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Acta Biochimica et Biophysica Sinica, 2023 Microtubules are hollow α/β-tubulin heterodimeric polymers that play critical roles in cells. In vertebrates, both α- and β-tubulins have multiple isotypes encoded by different genes, which are intrinsic factors in
Diao Lei +7 more
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Differential expression of liver fluke β-tubulin isotypes at selected life cycle stages
, 2013 We have shown that Fasciola hepatica expresses at least six β-tubulins in the adult stage of its life cycle, designated F.hep-β-tub1–6 (Ryan et al., 2008). Here we show that different complements of tubulin isotypes are expressed in different tissues and
Timson, David J. +8 more
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Microorganisms, 2022 Protozoans of the Phylum Ciliophora (ciliates) assemble many diverse microtubular structures in a single cell throughout the life cycle, a feature that made them useful models to study microtubule complexity and the role of tubulin isotypes.
Sandra Pucciarelli +6 more
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Microtubules in Microorganisms: How Tubulin Isotypes Contribute to Diverse Cytoskeletal Functions
Frontiers in Cell and Developmental Biology, 2022 The cellular functions of the microtubule (MT) cytoskeleton range from relatively simple to amazingly complex. Assembled from tubulin, a heterodimeric protein with α- and β-tubulin subunits, microtubules are long, hollow cylindrical filaments with ...
Abesh Bera, Mohan L. Gupta
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Antibodies in falciparum malaria: what matters most, quantity or quality?
Memorias do Instituto Oswaldo Cruz, 1992 In view of the recent demonstration that antibodies that are protective agains Plasmodium falciparum malaria may act in collaboration with blood monocytes, we have investigated the isotype content of sera from individuals with defined clinical states of ...
Hasnaa Bouharoun-Tayoun, Pierre Druilhe
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