Results 71 to 80 of about 1,269 (182)

Anticancer Potential of Xanthohumol and Isoxanthohumol Loaded into SBA-15 Mesoporous Silica Particles against B16F10 Melanoma Cells

Materials, 2022
Xanthohumol (XN) and isoxanthohumol (IXN), prenylated flavonoids from Humulus lupulus, have been shown to possess antitumor/cancerprotective, antioxidant, antiinflammatory, and antiangiogenic properties. In this study, mesoporous silica (SBA-15) was loaded with different amounts of xanthohumol and isoxanthohumol and characterized by standard analytical
Tamara Krajnović, Nebojša Đ. Pantelić, Katharina Wolf, Thomas Eichhorn, Danijela Maksimović-Ivanić, Sanja Mijatović, Ludger A. Wessjohann, Goran N. Kaluđerović   +7 more
openaire   +5 more sources

The hop-derived compounds xanthohumol, isoxanthohumol and 8-prenylnaringenin are tight-binding inhibitors of human aldo-keto reductases 1B1 and 1B10

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
Xanthohumol (XN), a prenylated chalcone unique to hops (Humulus lupulus) and two derived prenylflavanones, isoxanthohumol (IX) and 8-prenylnaringenin (8-PN) gained increasing attention as potential anti-diabetic and cancer preventive compounds.
Jan Moritz Seliger, Livia Misuri, Edmund Maser, Jan Hintzpeter   +3 more
doaj   +1 more source

Major Bioactive Prenylated Flavonoids from Humulus lupulus L., Their Applications in Human Diseases and Structure-Activity Relationships (SAR) – A Review [PDF]

Pharmaceutical Sciences
In recent years, the incidence of cancers, inflammatory diseases, Alzheimer’s disease, glucose metabolism disorder and diabetes has increased alarmingly which demands more research into the discovery of new drug candidates to treat these human diseases ...
Ferah Comert Onder, Sevil Kalin, Nebahat Sahin, Gulce Davutlar, Khaled A.N. Abusharkh, Ozlem Maraba, Rabia Selina Hal, Mehmet Ay, Lutfun Nahar, Satyajit D. Sarker   +9 more
doaj   +1 more source

DFT study of the radical scavenging activity of isoxanthohumol, humulones (α-acids), and iso-α-acids from beer [PDF]

, 2021
Humulones and iso-humulones are potent natural antioxidants found in beer. In this study, density functional theory (DFT) method was applied for elucidating the structure-antioxidant activity relationship and molecular mechanism of antioxidant activity ...
Bigović, M, Cvijetić, I, Milojković-Opsenica, D, Ristivojević, P, Vitorović-Todorović, M, Zloh, M   +5 more
core  

Isoxanthohumol reduces neointimal hyperplasia through the apelin/AKT pathway

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
The abnormal proliferation, migration, and inflammation of vascular smooth muscle cells (VSMCs) play crucial roles in the development of neointimal hyperplasia and restenosis. Exposure to inflammatory cytokines such as platelet-derived growth factor (PDGF)-BB and tumour necrosis factor-alpha (TNF-α) induces the transformation of contractile VSMCs into ...
Ting-Yu, Chang, Mao-Shin, Lin, Chin-Chuan, Chen, Yann-Lii, Leu, Shu-Huei, Wang   +4 more
openaire   +2 more sources

Characterization of Bioactive Compounds and Evaluation of Antimicrobial Activity of Humulus lupulus (L.) cv. Cascade Leaves Throughout the Growing Season

Journal of Sustainable Agriculture and Environment, Volume 4, Issue 3, September 2025.
ABSTRACT Hop (Humulus lupulus L.) is recognised for its abundance of bioactive compounds, which make it a valuable natural resource. While much of the research has focused on the cones, hop leaves remain relatively unexplored, particularly in terms of changes occurring throughout the plant's growing cycle.
Leandra Leto, Claudia Favari, Annalisa Ricci, Lorenzo Del Vecchio, Andrea Di Fazio, Anna Agosti, Margherita Rodolfi, Letizia Bresciani, Pedro Mena, Valeria Guarrasi, Valentina Bernini, Martina Cirlini, Tommaso Ganino, Benedetta Chiancone   +13 more
wiley   +1 more source

The Evaluation of Prenylflavonoids Compounds in Romanian Beer [PDF]

, 2011
The evalution of prenylflavonoids from Romanian beer was done by an analytical methodology based on sample purification by centrifugation and subsequent analysis of the beer by high performance liquid chromatography with mass spectrometry MS/MS detection.
MUDURA, Elena, PAUCEAN, Adriana, SOCACI, Sonia, TOFANA, Maria   +3 more
core   +2 more sources

Moderate Beer Consumption Ameliorated Aging‐Related Metabolic Disorders Induced by D‐Galactose in Mice via Modulating Gut Microbiota Dysbiosis

Food Science &Nutrition, Volume 13, Issue 8, August 2025.
The present study conducted a comparative analysis of the effects of moderate consumption of three prevalent beer types—Original beer, India Pale Ale (IPA), and Stout—on D‐galactose‐induced aging in mice. The findings demonstrate that the tested beers exhibit potential in mitigating metabolic disorders encompassing oxidative stress, inflammation levels,
Xueyuan Fu, Changwei Wang, Zhaoxia Yang, Junhong Yu, Jianfeng Wang, Wanxiu Cao, Chuyi Liu, Hua Yin, Bafang Li, Xiaomei Feng, Fen Du, Hu Hou   +11 more
wiley   +1 more source

Determination of Concentration of Prenylated Flavonoids and Analysis of Physicochemical Parameters of Beers Available on the Polish Market

Beverages
A total of 35 commercially available beers (of various beer styles) produced in Poland were analysed in this study to assess the concentration of xanthohumol and isoxanthohumol, prenylated flavonoids originating from the hops, which are known to possess ...
Alan Gasiński, Józef Błażewicz, Przemysław Leszczyński, Mirosław Anioł, Joanna Kawa-Rygielska   +4 more
doaj   +1 more source

Mouthfeel of Food and Beverages: A Comprehensive Review of Physiology, Biochemistry, and Key Sensory Compounds

Comprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 4, July 2025.
ABSTRACT Mouthfeel is a complex and multidimensional sensory experience that plays an important role in how people perceive flavor and accept food and beverages. Although it is a key part of the eating and drinking experience, mouthfeel is still not clearly defined and is difficult to measure. This review explores mouthfeel from a flavor perspective by
Katarzyna Wolinska‐Kennard, Christina Schönberger, Adam Fenton, Aylin W. Sahin   +3 more
wiley   +1 more source