Results 11 to 20 of about 5,265 (218)
Synthesis of Some Fused Pyrazoles and Isoxazoles
Molecules, 2000 The α-keto methylene group in 3,5-diaryl-2-cyclohexenones 2 and 3,5-diarylcyclohexanones 8 have been used to obtain fused pyrazoles and isoxazoles. The new compounds were characterized by IR and 1H-NMR spectral data.
Venkatapuram Padmavathi
exaly +4 more sources
Synthesis of Fused Isoxazoles: A Comprehensive Review
Engineering ProceedingsPharmaceutically important isoxazoles are within the wide range of heterocycles. The isoxazole ring, being five-membered, is also found in many bioactive natural products in addition to synthetic drugs.
Niveditha N. Mallik +5 more
doaj +2 more sources
Regioselective approach to 5-arylsulfonylisoxazoles and their antimicrobial activity [PDF]
Beilstein Journal of Organic ChemistryThis study presents a novel regioselective synthesis of 3-electron-withdrawing-group-(EWG)-substituted 5-sulfonyl- and 5-sulfinylisoxazoles from 3-EWG-5-nitroisoxazoles via nucleophilic aromatic substitution with thiophenols followed by oxidation with m ...
Artem S. Sazonov +9 more
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Divergent photochemical ring-replacement of isoxazoles [PDF]
Nature CommunicationsIsoxazoles, oxazoles, and other five-membered heteroaromatics are prevalent motifs in core structure of pharmaceuticals and agrochemicals. In early-stage drug discovery, it is common practice to prepare libraries of analogues featuring different ...
Yan Xu +5 more
doaj +2 more sources
Four-Component Reactions for the Synthesis of Perfluoroalkyl Isoxazoles
ACS Catalysis, 2019 A four-component strategy for the synthesis of the isoxazole skeleton is developed. The approach achieves the synthesis of perfluoroalkyl isoxazoles by using simple perfluoroalkyl reagents. In addition, the unprecedented 3-azido-5-arylisoxazole formation
Yuanjin Chen, Xiao He, Zhiping Li
exaly +3 more sources
Azirinyl-Substituted Nitrile Oxides: Generation and Use in the Synthesis of Isoxazole Containing Heterocyclic Hybrids [PDF]
MoleculesThe procedure for the generation of azirinyl-substituted nitrile oxides by the reaction of 2-(diazoacetyl)-2H-azirines with tert-butyl nitrite while preserving the azirine ring has been developed.
Alexander S. Dudik +4 more
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Synthesis of 2H-azirine-2,2-dicarboxylic acids and their derivatives [PDF]
Beilstein Journal of Organic ChemistryMethods for the preparation of 3-aryl-2H-azirine-2,2-dicarboxylic acids and their amides, esters, and azides by FeCl2-catalyzed isomerization of 3-aryl-5-chloroisoxazole-4-carbonyl chlorides into 3-aryl-2H-azirine-2,2-dicarbonyl dichlorides followed by ...
Anastasiya V. Agafonova +2 more
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A novel synthesis of 1,2,4-oxadiazoles and isoxazoles
Tetrahedron, 2014 A novel synthesis of 1,2,4-oxadiazoles and isoxazoles is described by utilizing the reactions between amidoximes and alpha,beta-alkynic aldehydes and/or ketones.
Arif Kivrak, Metin Zora
exaly +2 more sources
Síntesis y evaluación “in vitro” de la actividad antifúngica de oximas, éteres de oxima e isoxazoles
Universitas Scientiarum, 2011 Synthesis and in vitro assessment of antifungal activity of oximes, oxime ethers and isoxazoles. Objective. To synthesize and carryout a preliminary evaluation of the in vitro antifungal activity of oximes, oxime ethers and isoxazoles.
John Diaz-Velandia +3 more
doaj +1 more source
, 2019 Cu(II)-catalyzed [4+2]-cycloadditions occur between Cu–benzopyryliums and substituted isoxazoles with the regioselectivity on the C(3,4)-carbons of isoxazoles.
Sovan Sundar Giri (6988292) +3 more
core +7 more sources