Results 41 to 50 of about 5,810 (212)
EcoEnergy, EarlyView.This review introduces rate matching as a unifying design principle for efficient electrochemical C−N coupling and highlights multidimensional engineering of catalysts, interfaces, and reactors to synchronize the generation of carbon‐ and nitrogen‐containing intermediates, balance their surface coverages, maximize C−N bond formation, and enable ...
Kaixing Cai +4 more
wiley +1 more source
Iterative Assembly of Nitrile Oxides and Ynamides: Synthesis of Isoxazoles and Pyrroles
, 2019 Described is an iterative assembly of nitrile oxides and ynamides for the synthesis of isoxazoles and pyrroles. The nitrile oxides could undergo Cu(I)-free cyclization with terminal ynamides for accessing isoxazoles, which could engage in another ...
Changwei Chen (4018946) +1 more
core +3 more sources
5-(Benzoyloxymethyl)isoxazole-3-carboxylic Acid Ethyl Ester
MolbankWe describe here the palladium hydrogenation of ethyl 5-(benzoyloxymethyl)isoxazole-3-carboxylate. The presence of two reducible sites in the molecule, namely the benzylic-like position and the isoxazole N–O bond, creates a possible competition.
Cosimo Antonini +2 more
doaj +1 more source
Epileptic Disorders, EarlyView.Abstract Objective To compare the incidence of hostility‐ and aggression‐related adverse events in children with focal‐onset seizures (FOS), with or without focal to bilateral tonic–clonic seizures (FBTCS), receiving perampanel as monotherapy or in combination with other antiseizure medications (ASMs).
Yukitoshi Takahashi +5 more
wiley +1 more source
A facile synthesis of 3-cyclopropyl- and 5-cyclopropyl-isoxazoles
, 1999 The regioselective synthesis of isomeric isoxazoles 3-(2-arylcyclopropyl)-5-methylthio- and 5-(2-arylcyclopropyl)- 3-methylthio-isoxazoles is ...
Ila, H. +2 more
core +1 more source
Epilepsia, EarlyView.Abstract Anti‐seizure medication (ASM) discovery remains a major challenge despite over 30 commercially available options. One persistent obstacle for any promising candidate compound to successfully move from preclinical study to clinical approval has been the ambiguity in preclinical model selection.
Wolfgang Löscher +1 more
wiley +1 more source
Synthesis of Highly Reactive Ketenimines via Photochemical Rearrangement of Isoxazoles
, 2023 Ketenimines are highly electrophilic species with multiple applications as building blocks in organic synthesis; however, the effective preparation of these versatile entities remains a synthetic challenge.
Marcus Baumann (670318) +3 more
core +1 more source
The continuing significance of chiral agrochemicals
Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley +1 more source
Synthesis of natural products via isoxazoles
, 1987 Synthetic routes to natural products using isoxazole derivatives as key intermediates are reviewed. 1. Introduction 2. General Considerations 2.1. Methods of Preparation 2.2. Functionalization 2.3. Ring Opening Procedures 3. Synthesis of Natural Products
BENETTI, Simonetta +4 more
core +1 more source
Responsive Materials, EarlyView.Machine learning provides a unifying framework to connect structure, fluorescence properties, and applications of carbon‐based quantum dots. This review highlights how data‐driven strategies enable fluorescence regulation, reveal underlying mechanisms, and accelerate the rational design of functional carbon dots.
Liangfeng Chen +8 more
wiley +1 more source