Results 31 to 40 of about 5,265 (218)
Orbital: The Electronic Journal of Chemistry, 2020 Isoxazole is a five membered heterocyclic compound which is an azole with an oxygen atom next to nitrogen. The substituted isoxazole derivatives show various biological activities like antimicrobial, antiviral, anti-inflammatory, antioxidant, anticancer ...
Parul Setia, Ruchi Bharti, Renu Sharma
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Frontiers in Chemistry, 2019 Herein we report the use of Rhodiasolv© Polarclean as a novel polar aprotic solvent for the synthesis of decorated heterocycles via dipolar cycloaddition (isooxazoles) or intramolecular C–H functionalization processes (benzo-fused chromenes).
Francesco Ferlin +6 more
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Next MaterialsTwo isoxazoles sulfonamides namely N-butyl-2-(N-((3-(p-tolyl)isoxazol-5-yl)methyl)sulfamoyl)benzamide (IS-Cl) and N-butyl-2-(N-((3-(4-chlorophenyl)isoxazol-5-yl)methyl)sulfamoyl)benzamide (IS-CH3) were evaluated as some corrosion inhibitors for mild ...
Rachid Hsissou +8 more
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Synthesis of natural products via isoxazoles
, 1987 Synthetic routes to natural products using isoxazole derivatives as key intermediates are reviewed. 1. Introduction 2. General Considerations 2.1. Methods of Preparation 2.2. Functionalization 2.3. Ring Opening Procedures 3. Synthesis of Natural Products
BENETTI, Simonetta +4 more
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Isoxazolium N-ylides and 1-oxa-5-azahexa-1,3,5-trienes on the way from isoxazoles to 2H-1,3-oxazines
Beilstein Journal of Organic Chemistry, 2014 Theoretical and experimental studies of the reaction of isoxazoles with diazo compounds show that the formation of 2H-1,3-oxazines proceeds via the formation of (3Z)-1-oxa-5-azahexa-1,3,5-trienes which undergo a 6π-cyclization.
Alexander F. Khlebnikov +6 more
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Síntese regiosseletiva de cristais líquidos contendo o heterociclo isoxazol [PDF]
, 2008 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas. Programa de Pós-Graduação em QuímicaMoléculas com características líquido-cristalinas têm ultimamente atraído um grande interesse por parte de ...
Bryk, Fernando Rebouças
core
Heat Shock Protein 90: From Molecular Chaperone Function to Therapeutic Targeting in Malignancies
Advanced Science, EarlyView.In this review, an integrated conceptual framework linking HSP90's molecular chaperone functions to its pathological roles in cancer is proposed. HSP90 serves as a central node that integrates oncogenic signaling, buffers proteotoxic stress, maintains cancer stem cell plasticity, and shapes tumor‐immune interactions, all of which converge to drive ...
Beibei Zhang +4 more
wiley +1 more source
A facile synthesis of 3-cyclopropyl- and 5-cyclopropyl-isoxazoles [PDF]
, 1999 The regioselective synthesis of isomeric isoxazoles 3-(2-arylcyclopropyl)-5-methylthio- and 5-(2-arylcyclopropyl)- 3-methylthio-isoxazoles is ...
Ila, H. +2 more
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Relapses, Comorbidities, and Predictors of Outcome in Anti‐GABAA Receptor Encephalitis
Annals of Neurology, EarlyView.Objectives To characterize the magnetic resonance imaging (MRI) lesion dynamics, comorbidities, predictors of relapse, and outcomes in anti‐γ‐aminobutyric acid type A receptor (GABAAR) encephalitis, and assess the utility of LIM‐domain‐only‐protein 5 (LMO5) antibodies as tumor markers.
Claudia Papi +33 more
wiley +1 more source
Nitroimidazoles XIII. Synthesis of Substituted (1-Methyl-5-Nitro-2-Imidazolyl) Isoxazoles [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 1998 The beta0diketone derivatives of nitroimidazole were synthesized from the reaction of magnesium salt of beta-ketoaccids 3 with imidazolide 4. The raction of beta-diketones with hydroxylamine hydrochloride afforded either the isoxazoles or the 5-hydroxyl ...
Abbas Shafiee, Mohammad ALi Ebrahimzadeh
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