Results 51 to 60 of about 5,810 (212)

Synthesis of 4‑Sulfenyl Isoxazoles through AlCl₃‑Mediated Electrophilic Cyclization and Sulfenylation of 2‑Alkyn-1-one O‑Methyloximes

, 2019
An efficient method for the synthesis of 4-sulfenyl isoxazoles has been developed via AlCl3-mediated electrophilic cyclization/sulfenylation of 2-alkyn-1-one O-methyloximes.
Hong-Hong Chang (1696861), Wen-Chao Gao (1696867), Yu-Fei Cheng (4607086), Wen-Long Wei (1696858), Xing Li (134367), Peng Yang (296696)   +5 more
core   +2 more sources

Synthesis and Antimicrobial Activity of N′-Heteroarylidene-1-adamantylcarbohydrazides and (±)-2-(1-Adamantyl)-4-acetyl-5-[5-(4-substituted phenyl-3-isoxazolyl)]-1,3,4-oxadiazolines

Molecules, 2012
The reaction of adamantane-1-carbohydrazide (1) with heterocyclic aldehydes, namely 5-(4-chlorophenyl)isoxazole-3-carboxaldehyde (2a), 5-(4-methylphenyl)isoxazole-3-carboxaldehyde (2b), 5-(4-methoxyphenyl)isoxazole-3-carboxaldehyde (2c), 1H-imidazole-2 ...
Abdul-Malek S. Al-Tamimi, Ali A. El-Emam, Mohamed A. Al-Omar, Khalid A. Alrashood   +3 more
doaj   +1 more source

3-Benzoylisoxazolines by 1,3-Dipolar Cycloaddition: Chloramine-T-Catalyzed Condensation of α-Nitroketones with Dipolarophiles

Molecules, 2021
In this study, 3-benzoylisoxazolines were synthesized by reacting alkenes with various α-nitroketones using chloramine-T as the base. The scope of α-nitroketones and alkenes is extensive, including different alkenes and alkynes to form various ...
Xinhui Pan, Xiaobing Xin, Ying Mao, Xin Li, Yanan Zhao, Yidi Liu, Ke Zhang, Xiaoda Yang, Jinhui Wang   +8 more
doaj   +1 more source

Oxaziridines: Versatile Reagents in Modern Organic Synthesis

The Chemical Record, EarlyView.
Being capable of transferring an O atom and N‐group/atom, oxaziridines are considered multitasking agents. These are employed for diverse organic transformations, such as epoxidation of olefins, α‐ and γ‐hydroxylation/amination of carbonyl compounds, oxidation of sulfides, [3+2]cycloaddition with unsaturated systems.
Ajeet Chandra, Subba Rao Cheekatla, Keshaba Nanda Parida   +2 more
wiley   +1 more source

N‐methyl‐D‐aspartate receptor antagonists for controlling pain in dogs

Journal of Small Animal Practice, EarlyView.
This is a mini review published by the World Small Animal Veterinary Association's Pain Committee. This article provides an assessment of the scientific evidence of N‐methyl‐d‐aspartate receptor antagonists for controlling pain in dogs while identifying current knowledge gaps.
P. W. Kronen, B. D. X. Lascelles, B. P. Monteiro, J. C. Murrell, S. A. Robertson, P. V. Steagall, B. Wright   +6 more
wiley   +1 more source

Regioselective synthesis of heterocyclic N-sulfonyl amidines from heteroaromatic thioamides and sulfonyl azides

Beilstein Journal of Organic Chemistry, 2020
N-Sulfonyl amidines bearing 1,2,3-triazole, isoxazole, thiazole and pyridine substituents were successfully prepared for the first time by reactions of primary, secondary and tertiary heterocyclic thioamides with alkyl- and arylsulfonyl azides.
Vladimir Ilkin, Vera Berseneva, Tetyana Beryozkina, Tatiana Glukhareva, Lidia Dianova, Wim Dehaen, Eugenia Seliverstova, Vasiliy Bakulev   +7 more
doaj   +1 more source

Quantitative Pharmacodynamic Analysis of Trimethoprim‐Sulfonamide Combination Activity Against Staphylococcus pseudintermedius

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Trimethoprim (TMP)‐sulfonamide combinations are widely used in veterinary medicine, yet the quantitative nature of their pharmacodynamic interaction remains incompletely characterised. This study investigated the interaction between TMP and sulfamethoxazole (SMX), sulfadiazine (SDZ) and sulfadimethoxine (SDMX) against two Staphylococcus ...
Andrew Mead, Alexis Viel, Marine Boulanger, Gudrun Overesch, Carl Ekstrand, Pierre‐Louis Toutain, Aude A. Ferran, Ludovic Pelligand   +7 more
wiley   +1 more source

Isoxazole Derivatives as Regulators of Immune Functions

Molecules, 2018
In this review, we present reports on the immunoregulatory properties of isoxazole derivatives classified into several categories, such as immunosuppressive, anti-inflammatory, immunoregulatory, and immunostimulatory compounds.
Michał Zimecki, Urszula Bąchor, Marcin Mączyński   +2 more
doaj   +1 more source

Synthesis and biological evaluation of 4-phenoxy-phenyl isoxazoles as novel acetyl-CoA carboxylase inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
Acetyl-CoA carboxylase (ACC) is a crucial enzyme in fatty acid metabolism, which plays a major role in the occurrence and development of certain tumours.
Xin Wu, Yongbo Yu, Tonghui Huang
doaj   +1 more source

Iron dichloride induced isomerization or reductive cleavage of isoxazoles: A facile synthesis of 2-carboxy-azirines

, 1997
5-Alkoxy-isoxazoles and N,N-disubstituted-5-isoxazolamines were found to isomerize to azirine derivatives by the use of iron dichloride as catalyst.
A. Bini, AURICCHIO, SERGIO, E. Pastormerlo, TRUSCELLO, ADA, Ada M. Truscello, Eros Pastormerlo, Sergio Auricchio, Antonella Bini   +7 more
core   +1 more source