Results 61 to 70 of about 5,265 (218)

Acridine–Isoxazole and Acridine–Azirine Hybrids: Synthesis, Photochemical Transformations in the UV/Visible Radiation Boundary Region, and Anticancer Activity

Molecules
Easy-to-handle N-hydroxyacridinecarbimidoyl chloride hydrochlorides were synthesized as convenient nitrile oxide precursors in the preparation of 3-(acridin-9/2-yl)isoxazole derivatives via 1,3-dipolar cycloaddition with terminal alkynes, 1,1 ...
Ekaterina E. Galenko, Mikhail S. Novikov, Alexander S. Bunev, Alexander F. Khlebnikov   +3 more
doaj   +1 more source

Photocatalytic Vanadium‐Mediated Amination of Benzene With Hydroxylamine

Chemistry – A European Journal, Volume 32, Issue 22, 9 June 2026.
Photochemical activation of N‐phenylphenothiazine (PPT) enables a selective direct benzene amination with hydroxylamine in the presence of various vanadium catalysts under mild reaction conditions. Spectroscopic and kinetic analyses identify a key vanadium(IV)‐hydroxylamine intermediate, elucidate the crucial roles of the acidic medium, the ...
Dana Králová, Maximilian Philipp, Matthias Schmalzbauer, Thilo Reiter, Bernd Schäfer, Ruth M. Gschwind, Burkhard König   +6 more
wiley   +1 more source

Molecular Recognition by a Tris(phenylisoxazolyl)Benzene Derivative Under Flow‐Through Conditions

Advanced Sensor Research
The application of host molecules as separation media has attracted considerable attention owing to their intrinsic molecular recognition capabilities. Herein, we report the host–guest complexation behavior of a tris(phenylisoxazolyl)benzene derivative ...
Mao Kawasaki, Yudai Ono, Tomoko Amimoto, Takehiro Hirao, Takeharu Haino   +4 more
doaj   +1 more source

Regioselective synthesis of heterocyclic N-sulfonyl amidines from heteroaromatic thioamides and sulfonyl azides

Beilstein Journal of Organic Chemistry, 2020
N-Sulfonyl amidines bearing 1,2,3-triazole, isoxazole, thiazole and pyridine substituents were successfully prepared for the first time by reactions of primary, secondary and tertiary heterocyclic thioamides with alkyl- and arylsulfonyl azides.
Vladimir Ilkin, Vera Berseneva, Tetyana Beryozkina, Tatiana Glukhareva, Lidia Dianova, Wim Dehaen, Eugenia Seliverstova, Vasiliy Bakulev   +7 more
doaj   +1 more source

Bayesian Optimization of Solvent‐Free Thermal Amidation via Reactive Extrusion

Chemistry – A European Journal, Volume 32, Issue 22, 9 June 2026.
Thermal amidation between a carboxylic acid and an amine was successfully conducted in an extruder in the absence of solvent, coupling agent, or catalyst, relying on an adapted Bayesian Optimization protocol. Active pharmaceutical ingredient moclobemide was synthesized on a larger scale, achieving excellent yield and low Process Mass Intensity (PMI ...
Matthieu Lavayssiere, Xavier Bantreil, Frédéric Lamaty   +2 more
wiley   +1 more source

Isoxazole Derivatives as Regulators of Immune Functions

Molecules, 2018
In this review, we present reports on the immunoregulatory properties of isoxazole derivatives classified into several categories, such as immunosuppressive, anti-inflammatory, immunoregulatory, and immunostimulatory compounds.
Michał Zimecki, Urszula Bąchor, Marcin Mączyński   +2 more
doaj   +1 more source

Electrophilic Iodination of Heterocyclic Compounds. Recent Advances 2008–2025: Part II

European Journal of Organic Chemistry, Volume 29, Issue 22, 9 June 2026.
Electrophilic iodination using molecular iodine and iodide sources represents an efficient approach for accessing valuable iodinated organic compounds. This review highlights recent advances in the iodination of heterocyclic compounds from 2008 to 2025, emphasizing the role of heteroaryl iodides as important synthetic intermediates for biologically ...
Njomza Ajvazi, Stojan Stavber
wiley   +1 more source

Fluorescent Probes from Aromatic Polycyclic Nitrile Oxides: Isoxazoles versus Dihydro‐1λ3,3,2λ4‐Oxazaborinines

ChemistryOpen, 2019
Anthracenenitrile oxide undergoes 1,3‐dipolar cycloaddition reaction with propargyl bromide affording the expected isoxazole as single regioisomer, suitably synthetically elaborated and functionalized with a protected triple bond.
Dr. Mattia Moiola, Dr. Antonio Bova, Dr. Stefano Crespi, Dr. Misal G. Memeo, Prof. Mariella Mella, Prof. Herman S. Overkleeft, Dr. Bogdan I. Florea, Prof. Paolo Quadrelli   +7 more
doaj   +1 more source

Electron impact studies. XXXVII. Skeletal-rearrangement fragments in the mass spectra of alkyl and aryl isoxazoles

, 1969
The mass spectra of substituted isoxazoles are reported and discussed. The spectra of isoxazoles are strikingly different from those of oxazoles because the initial fragmentations of isoxazoles involve N-O bond fission.
RKMR Kallury, RG Cooks, JH Bowie
core   +1 more source

Síntesis de C-glicosil isoxazoles con potencial actividad biológica mediante adición 5-endo-trig de radicales iminoxilo catalizada por tempo [PDF]

, 2016
La síntesis de diversos C-glicosilmetil isoxazoles ha sido llevada a cabo mediante adición intramolecular 5-endo-trig de radicales iminoxilo generados a partir de cetoximas alfa, beta - insaturadas.
Llantén Martínez, Helberth Jesús
core   +1 more source