Results 231 to 240 of about 19,238 (306)

Effect of parecoxib on postoperative cognitive function and analgesic safety in elderly patients undergoing gastrointestinal tumor resection: A retrospective study. [PDF]

Biomol Biomed
Li Y, Peng Y.
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Tunable Key [3 + 2] and [2 + 1] Cycloaddition of Enaminones and α-Diazo Compounds for the Synthesis of Isomeric Isoxazoles: Metal-Controlled Selectivity.

Organic Letters, 2023
The three-component reactions of enaminones, α-diazo esters/ketones, and t-butyl nitrite (TBN) for the switchable synthesis of isomeric isoxazoles have been realized.
Wenli Song, Yunyun Liu, Nan Yan, Jie‐Ping Wan   +3 more
semanticscholar   +1 more source

Synthesis of Isoxazoles via One-Pot Oxidation/Cyclization Sequence from Propargylamines.

Journal of Organic Chemistry, 2022
A facile strategy for the synthesis of isoxazoles has been efficaciously developed, which involves oxidation of propargylamines to the corresponding oximes followed by CuCl-mediated intramolecular cyclization of the latter.
Mengyan Duan, G. Hou, Yabiao Zhao, Congjun Zhu, Chuanjun Song   +4 more
semanticscholar   +1 more source

Intermolecular [5 + 1]-Cycloaddition between Vinyl Diazo Compounds and tert-Butyl Nitrite to 1,2,3-Triazine 1-Oxides and Their Further Transformation to Isoxazoles.

Organic Letters, 2021
1,2,3-Triazine 1-oxides are formed by nitrosyl addition from tert-butyl nitrite to the vinylogous position of vinyl diazo compounds. This transformation, which is a formal intermolecular [5 + 1] cycloaddition, occurs under mild conditions, with high ...
Luca De Angelis, Haifeng Zheng, Matthew T Perz, Hadi D Arman, M. Doyle   +4 more
semanticscholar   +1 more source

Copper-Catalyzed Reductive Ring-Cleavage of Isoxazoles: Synthesis of Fluoroalkylated Enaminones and Application for the Preparation of Celecoxib, Deracoxib, and Mavacoxib.

Journal of Organic Chemistry, 2021
We have identified a new reactivity of copper/diamine catalysis for the reductive ring-cleavage of isoxazoles to yield fluoroalkylated enaminones.
C. Wan, Jian Pang, Wei-Qi Jiang, Xiao-Wei Zhang, Xiangguo Hu   +4 more
semanticscholar   +1 more source

Rapid Access to Benzimidazo[1,2-a]quinoline-Fused Isoxazoles via Pd(II)-Catalyzed Intramolecular Cross Dehydrogenative Coupling: Synthetic Versatility and Photophysical Studies.

Journal of Organic Chemistry, 2021
An efficient and atom-economical palladium-catalyzed intramolecular cross dehydrogenative coupling (CDC) reaction has been developed for the construction of highly π-conjugated benzimidazo[1,2-a]quinoline-fused isoxazole scaffolds using molecular oxygen ...
Subrata Sahoo, Shantanu Pal
semanticscholar   +1 more source

Recent Progress in the Synthesis of Isoxazoles

Current organic chemistry, 2021
Isoxazole derivatives are aromatic five-membered ring heterocyclic compounds with one oxygen atom and one nitrogen atom at adjacent positions.
D. Duc, V. C. Dung
semanticscholar   +1 more source

The isoxazole alkaloids

ChemInform, 2001
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Christophersen C, Rahbaek L
openaire   +4 more sources

Isoxazole anthelmintics

Journal of Medicinal Chemistry, 1977
A series of 3-halo-5-phenyl- and 3-phenyl-5-haloisoxazoles has demonstrated anthelmintic activity at doses ranging from 16 to 500 mg/kg orally against the rat roundworm, Nippostrongylus braziliensis. In the 5-phenyl series a halogen at the 3 position of the isoxazole ring was required for activity.
J B, Carr, H G, Durham, D K, Hass
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