Results 1 to 10 of about 135,785 (350)
PLoS ONE, 2013 BackgroundEven though itch is a common syndrome of many diseases there is only little knowledge about sex and gender differences in pruritus, especially in central itch perception and modulation.
Astrid Stumpf +7 more
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Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis [PDF]
eLife, 2019 Chronic itch remains a highly prevalent disorder with limited treatment options. Most chronic itch diseases are thought to be driven by both the nervous and immune systems, but the fundamental molecular and cellular interactions that trigger the ...
Carolyn M Walsh +11 more
doaj +3 more sources
Circuit dissection of the role of somatostatin in itch and pain [PDF]
Nature Neuroscience, 2018 Stimuli that elicit itch are detected by sensory neurons that innervate the skin. This information is processed by the spinal cord; however, the way in which this occurs is still poorly understood.
Hans Jürgen Solinski +2 more
exaly +3 more sources
Sensory TRP channels contribute differentially to skin inflammation and persistent itch
Nature Communications, 2017 Allergic contact dermatitis is associated both with persistent itch and inflammation, but it is not known if these are mediated by shared signaling pathways.
Jing Feng, Madison R Mack, Dariia Dryn
exaly +2 more sources
Spinal Calcrl+ neurons amplify mechanical itch signaling via synaptic plasticity in chronic itch model. [PDF]
PLoS ONEChronic itch, a devastating dermatological disorder, lacks targeted therapies due to incomplete understanding of its neural circuitry. Building on seminal studies that identified neuropeptide Y (NPY) inhibitory interneurons and their downstream urocortin
Huifeng Jiao +11 more
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Phase-Space Modeling and Control of Robots in the Screw Theory Framework Using Geometric Algebra
Mathematics, 2023 The following paper talks about the dynamic modeling and control of robot manipulators using Hamilton’s equations in the screw theory framework. The difference between the proposed work with diverse methods in the literature is the ease of obtaining the ...
Jesús Alfonso Medrano-Hermosillo +3 more
doaj +1 more source
Itch Beyond the Skin—Mucosal Itch [PDF]
Frontiers in Allergy, 2021 Itch is a nociceptive sensation linked with reflexes and cognitive motor actions. We traditionally think of itch as a sensation of the skin related to allergy, an insect sting or interestingly, anxiety and frustration. Less understood and considered are the physiological processes involved in the itching sensation that occurs at mucosal and junctional ...
Olivia J. Ly Lesslar +2 more
openaire +4 more sources
Acta Dermato-Venereologica, 2023 Crisaborole, a phosphodiesterase 4 (PDE4) inhibitor, has been approved for the treatment of mild to moderate atopic dermatitis. Atopic dermatitis is often associated with increased pain.
Darya Pavlenko +6 more
doaj +1 more source
Cells, 2020 Neurologic insults as varied as inflammation, stroke, and fibromyalgia elicit neuropathic pain and itch. Noxious sensation results when aberrantly increased afferent signaling reaches percept-forming cortical neurons and can occur due to increased sensory signaling, decreased inhibitory signaling, or a combination of both processes.
James Meixiong +2 more
openaire +3 more sources
Itch and neuropathic itch [PDF]
Pain, 2018 Abstract Neuropathic itch is a pathological condition that is due to damage within the nervous system. This type of itch can be severe and unrelenting, which has a very negative impact on quality of life. Neuropathic itch is more common than generally appreciated because most types of neuropathic pain have a neuropathic itch counterpart ...
Junichi, Hachisuka +2 more
openaire +2 more sources