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Itch Beyond the Skin—Mucosal Itch [PDF]
Frontiers in Allergy, 2021 Itch is a nociceptive sensation linked with reflexes and cognitive motor actions. We traditionally think of itch as a sensation of the skin related to allergy, an insect sting or interestingly, anxiety and frustration. Less understood and considered are the physiological processes involved in the itching sensation that occurs at mucosal and junctional ...
Olivia J. Ly Lesslar +2 more
openaire +4 more sources
Cells, 2020 Neurologic insults as varied as inflammation, stroke, and fibromyalgia elicit neuropathic pain and itch. Noxious sensation results when aberrantly increased afferent signaling reaches percept-forming cortical neurons and can occur due to increased sensory signaling, decreased inhibitory signaling, or a combination of both processes.
James Meixiong +2 more
openaire +3 more sources
Itch and neuropathic itch [PDF]
Pain, 2018 Abstract Neuropathic itch is a pathological condition that is due to damage within the nervous system. This type of itch can be severe and unrelenting, which has a very negative impact on quality of life. Neuropathic itch is more common than generally appreciated because most types of neuropathic pain have a neuropathic itch counterpart ...
Junichi, Hachisuka +2 more
openaire +2 more sources
Frontiers in Medicine, 2022 Itch and pain are common after burns. Neuropathic mechanisms may underlie both modalities but remain not well-understood. This study aims to prospectively document neuropathic pain symptoms and to identify potential itch symptom profiles that differ ...
N. E. E. Van Loey +5 more
doaj +1 more source
A spinal neural circuitry for converting touch to itch sensation
Nature Communications, 2020 Light touch can sometimes induce unpleasant itch sensation but the neural correlates of this conversion are not well studied. Here, the authors provide evidence that Tac2 expressing spinal interneurons are connected to gastrin-releasing peptide receptor (
Sihan Chen +11 more
doaj +1 more source
Attentional Bias Modification Training for Itch: A Proof-of-Principle Study in Healthy Individuals
Frontiers in Medicine, 2021 Itch draws our attention to allow imposing action against bodily harm (e.g., remove insects). At the same time, itch is found to interfere with ongoing tasks and daily life goals.
Antoinette I. M. van Laarhoven +10 more
doaj +1 more source
Frontiers in Medicine, 2021 Itch and worry about itch are predominant symptoms in atopic dermatitis (AD). Mindfulness refers to paying attention in a certain way, non-judgementally and on purpose. In patients with chronic pain, which shares several similarities with chronic itch, a
Kjell Lüßmann +6 more
doaj +1 more source
Assessing acute itch intensity : general labelled magnitude scale is more reliable than classic visual analogue scale [PDF]
, 2016 The reliable measurement of itch intensity is crucial, both in research as well as clinical contexts. For example, when the reliability of a measurement scale is unknown, it is impossible to determine whether a patient has changed sufficiently to be ...
Holle, Henning +3 more
core +2 more sources
The prelimbic cortex regulates itch processing by controlling attentional bias
iScience, 2023 Summary: Itch is a complex and unpleasant sensory experience. Recent studies have begun to investigate the neural mechanisms underlying the modulation of sensory and emotional components of itch in the brain.
Guang-Yan Wu +11 more
doaj +1 more source
Circuit dissection of the role of somatostatin in itch and pain [PDF]
, 2018 Stimuli that elicit itch are detected by sensory neurons that innervate the skin. This information is processed by the spinal cord; however, the way in which this occurs is still poorly understood.
AJ Christensen +79 more
core +1 more source