Results 11 to 20 of about 2,204 (211)
Frontiers in Medicine, 2022 Itch and pain are common after burns. Neuropathic mechanisms may underlie both modalities but remain not well-understood. This study aims to prospectively document neuropathic pain symptoms and to identify potential itch symptom profiles that differ ...
N. E. E. Van Loey +5 more
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A spinal neural circuitry for converting touch to itch sensation
Nature Communications, 2020 Light touch can sometimes induce unpleasant itch sensation but the neural correlates of this conversion are not well studied. Here, the authors provide evidence that Tac2 expressing spinal interneurons are connected to gastrin-releasing peptide receptor (
Sihan Chen +11 more
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Frontiers in Medicine, 2021 Itch and worry about itch are predominant symptoms in atopic dermatitis (AD). Mindfulness refers to paying attention in a certain way, non-judgementally and on purpose. In patients with chronic pain, which shares several similarities with chronic itch, a
Kjell Lüßmann +6 more
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Attentional Bias Modification Training for Itch: A Proof-of-Principle Study in Healthy Individuals
Frontiers in Medicine, 2021 Itch draws our attention to allow imposing action against bodily harm (e.g., remove insects). At the same time, itch is found to interfere with ongoing tasks and daily life goals.
Antoinette I. M. van Laarhoven +10 more
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The prelimbic cortex regulates itch processing by controlling attentional bias
iScience, 2023 Summary: Itch is a complex and unpleasant sensory experience. Recent studies have begun to investigate the neural mechanisms underlying the modulation of sensory and emotional components of itch in the brain.
Guang-Yan Wu +11 more
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Acta Dermato-Venereologica, 2022 Chronic itch can severely affect quality of life. Patients report that their chronic itch can be exacerbated by exposure to warm conditions (“warmth hyperknesis”).
Daniele Riccio +2 more
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Pain and itch coding mechanisms of polymodal sensory neurons
Cell Reports, 2023 Summary: Pain and itch coding mechanisms in polymodal sensory neurons remain elusive. MrgprD+ neurons represent a major polymodal population and mediate both mechanical pain and nonhistaminergic itch. Here, we show that chemogenetic activation of MrgprD+
Changxiong Guo +10 more
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Sensory TRP channels contribute differentially to skin inflammation and persistent itch
Nature Communications, 2017 Allergic contact dermatitis is associated both with persistent itch and inflammation, but it is not known if these are mediated by shared signaling pathways.
Jing Feng +12 more
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Brain, 2013 Research over the past 15 years has helped to clarify the anatomy and physiology of itch, the clinical features of neuropathic itch syndromes and the scientific underpinning of effective treatments. Two itch-sensitive pathways exist: a histamine-stimulated pathway that uses mechanically insensitive C-fibres, and a cowhage-stimulated pathway primarily ...
Amar, Dhand, Michael J, Aminoff
openaire +2 more sources