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Management of Itch in the Elderly: A Review
Chronic itch is common in the elderly patient and may be caused by a variety of known dermatologic and non-dermatologic conditions and can have a significant effect on quality of life.
Kayla M. Fourzali, Gil Yosipovitch
doaj +1 more source
Subliminal attentional bias modification training for itch
IntroductionItch is unpleasant and induces the urge to scratch. This is adaptive to remove the itch-inducing stimulus from the skin. Accordingly, itch draws attention to protect our bodily integrity.
Jennifer M. Becker +9 more
doaj +1 more source
A test-retest reliability study of human experimental models of histaminergic and non-histaminergic itch [PDF]
Numerous exploratory, proof-of-concept and interventional studies have used histaminergic and non-histaminergic human models of itch. However, no reliability studies for such surrogate models have been conducted.
Andersen, Hjalte Holm +7 more
core +2 more sources
Itch is an unpleasant cutaneous sensation that can arise following insect bites, exposure to plant ingredients, and some diseases. Itch can also have idiopathic causes. Itch sensations are thought to protect against external insults and toxic substances.
Hiroki Kittaka, Makoto Tominaga
doaj +1 more source
Recognition mechanism of p63 by the E3 ligase Itch Novel strategy in the study and inhibition of this interaction. [PDF]
The HECT-containing E3 ubiquitin ligase Itch mediates the degradation of several proteins, including p63 and p73, involved in cell specification and fate.
Barbato, G +4 more
core +1 more source
Do tonic itch and pain stimuli draw attention towards their location? [PDF]
Background. Although itch and pain are distinct experiences, both are unpleasant, may demand attention, and interfere with daily activities. Research investigating the role of attention in tonic itch and pain stimuli, particularly whether attention is ...
Crombez, Geert +5 more
core +5 more sources
Cross-inhibition of NMBR and GRPR signaling maintains normal histaminergic itch transmission [PDF]
We previously showed that gastrin-releasing peptide receptor (GRPR) in the spinal cord is important for mediating nonhistaminergic itch. Neuromedin B receptor (NMBR), the second member of the mammalian bombesin receptor family, is expressed in a largely ...
Barry, Devin M +12 more
core +2 more sources
Chronic itch can be caused by dysfunctions of itch-sensing neurons that produce sensory hallucinations of pruritogenic stimuli. The cellular and molecular mechanisms are still unknown. All neurological disease categories have been implicated, and neurological causes should be considered for patients with otherwise-unexplained itch.
openaire +3 more sources
Extracellular signal-regulated kinase (ERK) activation is required for itch sensation in the spinal cord [PDF]
BACKGROUND: Itch, chronic itch in particular, can have a significant negative impact on an individual’s quality of life. However, the molecular mechanisms underlying itch processing in the central nervous system remain largely unknown. RESULTS: We report
Guan-Yu Jiang +6 more
core +1 more source
Itching eyes after itching around the head
GMS Ophthalmology Cases; 10 ...
Tabuenca Del Barrio, L +3 more
openaire +4 more sources

