Results 21 to 30 of about 129,163 (299)

Mild Skin Heating Evokes Warmth Hyperknesis Selectively for Histaminergic and Serotoninergic Itch in Humans

open access: yesActa Dermato-Venereologica, 2022
Chronic itch can severely affect quality of life. Patients report that their chronic itch can be exacerbated by exposure to warm conditions (“warmth hyperknesis”).
Daniele Riccio   +2 more
doaj   +1 more source

Brain processing of contagious itch in patients with atopic dermatitis [PDF]

open access: yes, 2017
Several studies show that itch and scratching cannot only be induced by pruritogens like histamine or cowhage, but also by the presentation of certain (audio-) visual stimuli like pictures on crawling insects or videos showing other people scratching ...
Apkarian   +44 more
core   +3 more sources

Pain and itch coding mechanisms of polymodal sensory neurons

open access: yesCell Reports, 2023
Summary: Pain and itch coding mechanisms in polymodal sensory neurons remain elusive. MrgprD+ neurons represent a major polymodal population and mediate both mechanical pain and nonhistaminergic itch. Here, we show that chemogenetic activation of MrgprD+
Changxiong Guo   +10 more
doaj   +1 more source

Distinct roles of NMB and GRP in itch transmission [PDF]

open access: yes, 2017
A key question in our understanding of itch coding mechanisms is whether itch is relayed by dedicated molecular and neuronal pathways. Previous studies suggested that gastrin-releasing peptide (GRP) is an itch-specific neurotransmitter. Neuromedin B (NMB)
Bardoni, Rita   +16 more
core   +3 more sources

Sensory TRP channels contribute differentially to skin inflammation and persistent itch

open access: yesNature Communications, 2017
Allergic contact dermatitis is associated both with persistent itch and inflammation, but it is not known if these are mediated by shared signaling pathways.
Jing Feng   +12 more
doaj   +1 more source

Emerging Methods to Objectively Assess Pruritus in Atopic Dermatitis. [PDF]

open access: yes, 2019
INTRODUCTION:Atopic dermatitis (AD) is an inflammatory skin disease with a chronic, relapsing course. Clinical features of AD vary by age, duration, and severity but can include papules, vesicles, erythema, exudate, xerosis, scaling, and lichenification.
Bhutani, Tina   +7 more
core   +1 more source

Attentional Bias Towards Visual Itch and Pain Stimuli in Itch- and Pain-free Individuals?

open access: yesActa Dermato-Venereologica, 2020
Itch and pain are important attention-demanding sensations that allow adaptive responses to potential bodily harm. An attentional bias towards itch and pain stimuli, i.e.
Jennifer M. Becker   +6 more
doaj   +1 more source

Environmental influences on induction of itching and scratching using immersive virtual reality

open access: yesScientific Reports, 2023
Chronic itching is a serious and uncomfortable condition. The scratch response might result in a vicious cycle of alternating itching and scratching.
Emmy W. T. van de Burgt   +3 more
doaj   +1 more source

Glial cells are involved in itch processing [PDF]

open access: yes, 2016
Recent discoveries in itch neurophysiology include itch-selective neuronal pathways, the clinically relevant non-histaminergic pathway, and elucidation of the notable similarities and differences between itch and pain.
Andersen, Hjalte H.   +2 more
core   +2 more sources

Activity-dependent silencing reveals functionally distinct itch-generating sensory neurons [PDF]

open access: yes, 2014
The peripheral terminals of primary sensory neurons detect histamine and non-histamine itch-provoking ligands through molecularly distinct transduction mechanisms.
Bean, Bruce P.   +11 more
core   +1 more source

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