A disease mutation reveals a role for Nav1.9 in acute itch [PDF]
Itch (pruritis) and pain represent two distinct sensory modalities; yet both have evolved to alert us to potentially harmful external stimuli. Compared with pain, our understanding of itch is still nascent.
Bosmans, Frank +5 more
core +1 more source
Abstract Neuropathic itch is clinically important but has received much less attention as compared to neuropathic pain. In the past decade, itch-specific pathways have been characterized on a cellular and molecular level, but their exact role in the pathophysiology of neuropathic itch is still unclear.
Steinhoff M. +4 more
openaire +4 more sources
Effects of Psychological Stress on Spontaneous Itch and Mechanical Alloknesis of Atopic Dermatitis
Atopic dermatitis (AD), a chronic inflammatory skin disease, manifests as an intractable itch. Psychological stress has been suggested to play a role in the onset and worsening of AD symptoms.
Qiaofeng Zhao +9 more
doaj +1 more source
Straw Itch Mite, \u3ci\u3ePyemotes Tritici\u3c/i\u3e, Infestation in Brome Seed Related to Acute Dermatitis in Michigan Granary Workers [PDF]
An infestation of Pyemotes tritici, the straw itch mite, apparently caused dermatitis on the arms and trunks of four workers in south-central Michigan who had unloaded a shipment of brome seed bags.
Landis, Douglas A, Walker, Edward D
core +2 more sources
AbstractPsychogenic itch can be defined as “an itch disorder where itch is at the center of the symptomatology and where psychological factors play an evident role in the triggering, intensity, aggravation, or persistence of the pruritus.” The disorder is poorly known by both psychiatrists and dermatologists and this review summarizes data on ...
Misery, Laurent +5 more
openaire +2 more sources
Neuroimmune Mediators of Pruritus in Hispanic Scalp Psoriatic Itch
Scalp psoriatic itch is a common, bothersome, yet understudied, condition with numerous associated treatment challenges. The aim of this study was to enhance our understanding of the pathophysiology of scalp psoriatic itch.
Leigh A. Nattkemper +6 more
doaj +1 more source
A Randomized, Controlled, Phase 2 Study of Maralixibat in the Treatment of Itching Associated With Primary Biliary Cholangitis. [PDF]
Primary biliary cholangitis (PBC) is typically associated with elevated serum bile acid levels and pruritus, but pruritus is often refractory to treatment with existing therapies.
Apostol, George +15 more
core +2 more sources
Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus +6 more
wiley +1 more source
A tactile twist: decoding the phenomena of mechanical itch and alloknesis
Itch is a sensation in the skin which provokes the desire to scratch. In the past few decades there has been a significant elucidation of the immune and neural pathways which underly the sensation of itch.
Taylor Follansbee, Xinzhong Dong
doaj +1 more source
Identifying functional populations among the interneurons in laminae I-III of the spinal dorsal horn [PDF]
The spinal dorsal horn receives input from primary afferent axons, which terminate in a modality-specific fashion in different laminae. The incoming somatosensory information is processed through complex synaptic circuits involving excitatory and ...
Todd, Andrew J.
core +1 more source

