Results 81 to 90 of about 39,357 (305)
, 2019 Neuropathic itch is clinically important but has received much less attention as compared to neuropathic pain. In the past decade, itch-specific pathways have been characterized on a cellular and molecular level, but their exact role in the ...
Szab I.L. +4 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Contagious itch can be induced in humans but not in rodents
Molecular Brain, 2019 Itch contagion has been reported in human when people watch someone scratching in a video. The basic mechanism of contagious itch induced by scratching video is still being investigated.
Jing-Shan Lu +7 more
doaj +1 more source
Managing itch- a biopsychosocial approach to care.
, 2016 Itch is most often associated with inflammatory and non- inflammatory skin conditions, but can also manifest in other non-dermatological illnesses such as haematological conditions, malignant disease, endocrine disorders, hepatic and renal disease, human
Chouliara, Zo�, Buchanan, P
core
Age-dependent alterations in spermatogenesis in itchy mice [PDF]
, 2013 textSpermatogenesis is an intricate process that strongly depends on the rapid turnover of short-lived proteins, both in the differentiating germ cells and in the supportive Sertoli cells.
Dwyer, Jessica Leigh
core
Opposing effects of cervical spinal cold block on spinal itch and pain transmission
, 2018 Inactivation of descending pathways enhanced responses of spinal dorsal horn neurons to noxious stimuli, but little is known regarding tonic descending modulation of spinal itch transmission. To study effects of cervical spinal cold block on responses of
Auva Davoodi +9 more
core +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Psychophysiological Processing of Itch in Patients with Chronic Post-burn Itch: An Exploratory Study [PDF]
, 2016 A substantial proportion of patients with burn injury develop chronic itch, which can severely affect their quality of life. As found in research on chronic pain, different psychophysiological processes may also play a role in chronic itch, of which ...
van der Wee, Nic J A +9 more
core +2 more sources
Journal of Cutaneous Immunology and AllergyBackground: The nature of itch sensation varies depending upon the patient and the disease. However, few studies have focused on verbal expressions describing itch of atopic dermatitis (AD) in quality.Objectives: To investigate itch quality in patients ...
Yukihiro Ohya +22 more
doaj +1 more source
Pregabalin for postherpetic itch: a case report
JA Clinical Reports, 2020 Background Postherpetic itch has not commonly received attention as a complication of herpes zoster because pain predominates over itch in most patients with herpes zoster.
Nobuhiro Shimada +4 more
doaj +1 more source