Results 81 to 90 of about 42,908 (304)

Managing itch- a biopsychosocial approach to care.

, 2016
Itch is most often associated with inflammatory and non- inflammatory skin conditions, but can also manifest in other non-dermatological illnesses such as haematological conditions, malignant disease, endocrine disorders, hepatic and renal disease, human
Chouliara, Zo�, Buchanan, P
core  

Age-dependent alterations in spermatogenesis in itchy mice [PDF]

, 2013
textSpermatogenesis is an intricate process that strongly depends on the rapid turnover of short-lived proteins, both in the differentiating germ cells and in the supportive Sertoli cells.
Dwyer, Jessica Leigh
core  

Neuropathic itch

, 2019
Neuropathic itch is clinically important but has received much less attention as compared to neuropathic pain. In the past decade, itch-specific pathways have been characterized on a cellular and molecular level, but their exact role in the ...
Szab I.L., Steinhoff M., Schmelz M., Stnder S., Oaklander A.L.   +4 more
core   +1 more source

Neuropathic Itch

, 2020
Neurologic insults as varied as inflammation, stroke, and fibromyalgia elicit neuropathic pain and itch. Noxious sensation results when aberrantly increased afferent signaling reaches percept-forming cortical neurons and can occur due to increased ...
James Meixiong, Hao-Jui Weng, Xinzhong Dong   +2 more
core   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Verbal expressions describing itch quality in atopic dermatitis and urticaria: an online questionnaire survey in Japan

Journal of Cutaneous Immunology and Allergy
Background: The nature of itch sensation varies depending upon the patient and the disease. However, few studies have focused on verbal expressions describing itch of atopic dermatitis (AD) in quality.Objectives: To investigate itch quality in patients ...
Yukihiro Ohya, Toshiya Ebata, Yusei Ohshima, Tsugunobu Andoh, Mitsutoshi Tominaga, Yoko Kataoka, Yoshinori Fukui, Nobuyuki Ebihara, Shunji Hasegawa, Shigetoshi Kobayashi, Yutaka Morisawa, Norihiro Inoue, Masami Narita, Sakae Kaneko, Ken Igawa, Takeshi Nakahara, Yozo Ishiuji, Takaharu Okada, Masanori Fujii, Hiroshi Kawasaki, Hiroyuki Irie, Miho Shiratori-Hayashi, Hiroyuki Murota   +22 more
doaj   +1 more source

Pregabalin for postherpetic itch: a case report

JA Clinical Reports, 2020
Background Postherpetic itch has not commonly received attention as a complication of herpes zoster because pain predominates over itch in most patients with herpes zoster.
Nobuhiro Shimada, Yasunori Niwa, Kunihisa Hotta, Takashi Igarashi, Mamoru Takeuchi   +4 more
doaj   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Opposing effects of cervical spinal cold block on spinal itch and pain transmission

, 2018
Inactivation of descending pathways enhanced responses of spinal dorsal horn neurons to noxious stimuli, but little is known regarding tonic descending modulation of spinal itch transmission. To study effects of cervical spinal cold block on responses of
Auva Davoodi, Davoodi, Auva, Nagamine, Masaki, Mirela Iodi Carstens, Tasuku Akiyama, Masaki Nagamine, Carstens, Earl, Carstens, Mirela Iodi, Akiyama, Tasuku, Earl Carstens   +9 more
core   +1 more source

Interneurons Scratch an Itch [PDF]

, 2014
Itch is immensely frustrating. Most studies focus on the cause of itch. In this issue of Neuron, Kardon et al. (2014) find that itch can be modulated by inhibitory neurons that produce dynorphin, an endogenous agonist of κ-opioid ...
Pereira, Paula Juliana Seadi, Lerner, Ethan A.   +1 more
core   +1 more source