Results 101 to 110 of about 3,221,249 (291)

Testing the properties of the Eco-Anxiety questionnaire (EAQ) for exploring eco-anxiety phenomenon

Mediterranean Journal of Clinical Psychology
Introduction. Eco-anxiety has gained attention in recent years. While anxiety is typically viewed as a disorder, eco-anxiety may also be seen as a rational response to environmental threats, potentially driving pro-environmental behavior.
Giuseppe Forte, Francesca Favieri, Renata Tambelli, Maria Casagrande   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Assessment of Distractor Functionality in Multiple Choice Questions: Student Generated Versus Teacher Generated Distractors

Medical Journal of Dr. D.Y. Patil Vidyapeeth
Introduction: Distractors for multiple-choice questions can be obtained by various models like expert judgment, software auto-generation, or from student misconception.
J Annie Sheeba, Nilakantan Ananthakrishnan, Charulatha Ravindran, VR Hemanth Kumar   +3 more
doaj   +1 more source

An average-case analysis of bin packing with uniformly distributed item sizes [PDF]

, 1982
We analyze the one-dimensional bin-packing problem under the assumption that bins have unit capacity, and that items to be packed are drawn from a uniform distribution on [0,1].
Lueker, George S.
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Comparison of Item Difficulty Analyses of Exams Used in Teaching Turkish as a Foreign Language with Instructors’ Perceptions of Item Difficulty

Sakarya University Journal of Education
In numerous studies focusing on assessment and evaluation of teaching Turkish as a foreign language, researchers have frequently identified issues related to the standardization and low validity and reliability of exams.
Seçil Alaca, Funda Keskin
doaj   +1 more source

Improving the measurement of QALYs in dementia: developing patient- and carer-reported health state classification systems using Rasch analysis [PDF]

Objectives: Cost-utility analysis is increasingly used to inform resource allocation. This requires a means of valuing health states before and after intervention. Although generic measures are typically used to generate values, these do not perform well
Banerjee, S, Brazier, JE, Howard, RJ, Knapp, M, Lamping, DL, Loftus, V, Mulhern, B, Rowen, D, Smith, SC, Young, Tracey A.   +9 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Constructing psychometric measurement of a past supervised experience scale with educational roles to investigate the relationship between being instructed, being supported, and being supervised for attending physicians in teaching hospitals – a questionnaire survey

Medical Education Online
Purpose Although school-based planned education has steadily been introduced, master-apprentice learning is still an indispensable part of medical education.
Yu-Chih Lin, Ling-Chun Ou
doaj   +1 more source