Results 61 to 70 of about 1,038,246 (291)

Cognitive Functioning in Vorinostat‐Treated Pediatric and Young Adult Patients Over the First 180 Days After Hematopoietic Stem Cell Transplant

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Cognitive and psychological difficulties could negatively interfere with treatment adherence and quality of life before and after hematopoietic stem cell transplant (HSCT). Methods to mitigate these changes may have positive effects on treatment success.
Kristen L. Votruba, Michelle Rozwadowski, Thomas Braun, April Rahrig, Edward Peres, Kirsten M. Williams, Vanessa Fabrizio, Julie‐An Talano, Carrie L. Kitko, Nicolas Parnell, Pavan Reddy, Sung Won Choi   +11 more
wiley   +1 more source

The difference between estimated and perceived item difficulty: An empirical study

International Journal of Assessment Tools in Education
Test development is a complicated process that demands examining various factors, one of them being writing items of varying difficulty. It is important to use items of a different range of difficulty to ensure that the test results accurately indicate ...
Okan Bulut, Ayfer Sayın
doaj   +1 more source

The relationship between phonological and morphological deficits in Broca's aphasia: further evidence from errors in verb inflection [PDF]

, 2005
A previous study of 10 patients with Broca’s aphasia demonstrated that the advantage for producing the past tense of irregular over regular verbs exhibited by these patients was eliminated when the two sets of past-tense forms were matched for ...
Braber, N, Ellis, K, McClelland, JL, Patterson, K, Ralph, MAL   +4 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Impact of simple substitution methods for missing data on Classical test theory difficulty and discrimination [PDF]

Tutorials in Quantitative Methods for Psychology, 2018
In Classical test theory, difficulty ($p$) and discrimination ($d$) are two item coefficients that are widely used to analyze and validate items in educational testing.
Béland, Sébastien, Jolani, Shahab, Pichette, Fran{\c {c}}ois, Renaud, Jean-Sébastien   +3 more
doaj   +1 more source

Development and validation of the ACE tool: Assessing medical trainees' competency in evidence based medicine [PDF]

, 2014
BACKGROUND: While a variety of instruments have been developed to assess knowledge and skills in evidence based medicine (EBM), few assess all aspects of EBM - including knowledge, skills attitudes and behaviour - or have been psychometrically evaluated.
A McCluskey, D George, D Ilic, D Ilic, D Ilic, D Sackett, Dragan Ilic, E Dinkevich, E Meats, Elmer Villanueva, G Guyatt, J Fliegel, J Jones, J Nunnally, J Spencer, J Tilson, J Tilson, Julie K Tilson, K Ramos, L Aiken, L Fritsche, M Dawes, P Kline, Paul Glasziou, R Ebel, R Jackson, Rusli Bin Nordin, T Shaneyfelt   +27 more
core   +2 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

EXAMINING THE RELATIONSHIP BETWEEN DIFFERENTIAL ITEM FUNCTIONING AND ITEM DIFFICULTY [PDF]

ETS Research Report Series, 1989
ABSTRACTThis study examined the relationship of differential item functioning (DIF) to item difficulty on the Scholastic Aptitude Test (SAT). The data comprise verbal and mathematical item statistics from nine recent administrations of the SAT. In general, item difficulty is related to DIF.
Edward Kulick, P. Gillian Hu
openaire   +1 more source

Insomnia as an Independent Predictor of Incident Cardiovascular Disease in HIV: Data from the Veterans Aging Cohort Study [PDF]

, 2019
Background: Insomnia is associated with increased cardiovascular disease (CVD) risk in the general population and is highly prevalent in people with HIV. The CVD risk conferred by insomnia in the HIV population is unknown.
Bedimo, Roger J., Budoff, Matthew J., Butt, Adeel A., Chang, Chung-Chou H., Freiberg, Matthew S., Gottlieb, Stephen S., Gupta, Samir K., Kundu, Suman, Marconi, Vincent C., Polanka, Brittanny M., So-Armah, Kaku A., Stewart, Jesse C., Womack, Julie A.   +12 more
core   +1 more source