Results 41 to 50 of about 6,770,640 (284)

The impact of item-writing flaws and item complexity on examination item difficulty and discrimination value [PDF]

open access: yes, 2016
Citation: Rush, B. R., Rankin, D. C., & White, B. J. (2016). The impact of item-writing flaws and item complexity on examination item difficulty and discrimination value. BMC Medical Education, 16(1).
Bonnie R. Rush   +5 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Evaluating an electricity and magnetism assessment tool: Brief electricity and magnetism assessment

open access: yesPhysical Review Special Topics. Physics Education Research, 2006
The Brief Electricity and Magnetism Assessment (BEMA), developed by Chabay and Sherwood, was designed to assess student understanding of basic electricity and magnetism concepts covered in college-level calculus-based introductory physics courses.
Lin Ding   +3 more
doaj   +2 more sources

Item analyses of the 20-item prosopagnosia index using classical test theory and item response theory. [PDF]

open access: yesBehav Res Methods
The 20-item prosopagnosia index (PI20) is a highly practical tool for assessing lifelong difficulties in face processing across individuals (developmental prosopagnosia).
Mori M, Sugiyama M.
europepmc   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Item parameters of Yureka Education Center (YEC) English Proficiency Online Test (EPOT) instrument

open access: yesREID (Research and Evaluation in Education), 2020
Yureka Education Center (YEC) is one of the institutions which has developed an online-based English proficiency test. The test is called the English Proficiency Online Test (EPOT) which follows the TOEFL ITP (Institutional Testing Program) framework ...
Endrati Jati Siwi   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Impact of INR on mortality: Net-reclassification-index and integrated-discrimination-index.

open access: yes, 2019
Impact of INR on mortality: Net-reclassification-index and integrated-discrimination-index.
Andreas Zirlik (178884)   +6 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Item difficulty and discrimination.

open access: yes, 2019
Item difficulty and discrimination.
Olanrewaju O. Oyedepo (6294005)   +9 more
core   +1 more source

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