Results 61 to 70 of about 229,991 (298)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Item analysis of multiple choice questions from assessment of health sciences students, Tigray, Ethiopia

BMC Medical Education
Background Rapid expansion of higher education and graduation rate in Ethiopia, doesn’t tell much about quality of core processes like teaching and learning. Despite the fact that preparation of a good item is essential, little attention has been paid to
Mengistu Welday Gebremichael, Beyene Baraki, Mihret-Ab Mehari, Betel Assalfew   +3 more
doaj   +1 more source

Tepatkah Nijmeegse Schoolbekwaamheids test (NST) untuk mengukur kesiapan sekolah siswa sekolah dasar awal pada konteks Indonesia? (Analisis empirik berdasar teori tes klasik)

Jurnal Ilmiah Psikologi Terapan, 2016
Nijmeegse Schoolbekwaamheids Test (NST) was a test to measure the readiness of children attend primary school. This research was a descriptive study that aims to determine the quality of the NST was empirically based on classical test theory as an ...
Lely Ika Mariyati, Ghozali Rusyid Affandi   +1 more
doaj   +1 more source

Item statistics derived from three-option versions of multiple-choice questions are usually as robust as four- or five-option versions: implications for exam design. [PDF]

, 2018
Different versions of multiple-choice exams were administered to an undergraduate class in human physiology as part of normal testing in the classroom. The goal was to evaluate whether the number of options (possible answers) per question influenced the ...
Loudon, Catherine, Macias-Muñoz, Aide
core  

Workplace Contextual Supports for LGBT Employees: A Review, Meta‐Analysis, and Agenda for future Research [PDF]

, 2018
The past decade has witnessed a rise in the visibility of the lesbian, gay, bisexual, and transgender (LGBT) community. This has resulted in some organizational researchers focusing their attention on workplace issues facing LGBT employees.
Allan, Allen, Anderson, Androsiglio, Armstrong, Badgett, Balzer, Barak, Baruch-Feldman, Becker, Beehr, Bennett, Blau, Bowen, Boyles, Brackmann, Brenner, Brewster, Brooks, Budescu, Butler, Button, Button, Cameron, Cammann, Caplan, Carr, Chrobot-Mason, Clair, Cobb, Cohen, Combs, Croteau, Croteau, Curtis, Dawis, Day, Day, Derogatis, Drake, Driscoll, Dwertmann, Eisenberger, Eisenberger, Ellis, Fasoli, Ferris, Frankenhaeueser, Friskopp, Ganster, Gardner, Gates, Gould-Williams, Grant, Griffith, Hasenbush, Hebl, Herek, Hope Pelled, House, Huebner, Huffman, Hunter, Hunter, Ironson, James, James, Ji, Johnston, Judge, Kahn, Kehoe, King, King, Konrad, Kossek, Kristof, Kulik, Law, Liddle, Macky, Martin, Martin, May, McDermott, McKay, Meyer, Meyer, Meyer, Mohr, Mowday, Munoz, Norton, Osipow, Ostroff, Parker, Parker, Passani, Posthuma, Quinn, Quinn, Quinn, Rabelo, Ragins, Ragins, Ragins, Ragins, Rankin, Reed, Roberson, Robinson, Rostosky, Ruggs, Saari, Sabat, Schaufeli, Schein, Schein, Sears, Smith, Spence, Spreitzer, Subramony, Tejeda, Thoits, Trau, Ueno, Velez, Viswesvaran, Waldo, Weiss   +130 more
core   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

The characteristics of chemistry test items on nationally-standardized school examination in Yogyakarta City

REID (Research and Evaluation in Education), 2021
This study aimed to describe the characteristics of chemistry test items in Nationally Standardized School Examination or Ujian Sekolah Berstandar Nasional (USBN), consisted of discrimination index, difficulty index, and question reliability.
Ummul Karimah, Heri Retnawati, Deni Hadiana, Pujiastuti Pujiastuti, Eri Yusron   +4 more
doaj   +1 more source

ANALISIS SOAL LATIHAN PEMBELAJARAN KOSAKATA BAHASA PERANCIS DALAM MULTIMEDIA INTERAKTIF DUOLINGO [PDF]

, 2016
Saat ini muncul beragam situs dan aplikasi bertema edukasi untuk menunjang pembelajaran yang termasuk ke dalam media interaktif, salah satunya Duolingo.
Badriyah, Rima
core  

Item analysis: the impact of distractor efficiency on the difficulty index and discrimination power of multiple-choice items

BMC Medical Education
Abstract Background Distractor efficiency (DE) of multiple-choice questions (MCQs) responses is a component of the psychometric analysis used by the examiners to evaluate the distractors’ credibility and functionality. This study was conducted to evaluate the impact of the DE on the difficulty and discrimination indices.
Assad Ali Rezigalla, Ali Mohammed Elhassan Seid Ahmed Eleragi, Amar Babikir Elhussein, Jaber Alfaifi, Mushabab A. ALGhamdi, Ahmed Y. Al Ameer, Amar Ibrahim Omer Yahia, Osama A. Mohammed, Masoud Ishag Elkhalifa Adam   +8 more
openaire   +3 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source