Results 71 to 80 of about 400,137 (262)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Exploration and analysis of a generalized one-parameter item response model with flexible link functions. [PDF]

Front Psychol, 2023
Wang X, Zhang J, Lu J, Cheng G, Shi N.
europepmc   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Linking Error Estimation in Fixed Item Parameter Calibration: Theory and Application in Large-Scale Assessment Studies

Foundations
In fixed item parameter calibration (FIPC), an item response theory (IRT) model is estimated with item parameters fixed at reference values to estimate the distribution parameters within a specific group.
Alexander Robitzsch
doaj   +1 more source

An Evaluation of Overall Goodness-of-Fit Tests for the Rasch Model

Frontiers in Psychology, 2019
For assessing the fit of item response theory models, it has been suggested to apply overall goodness-of-fit tests as well as tests for individual items and item pairs.
Rudolf Debelak
doaj   +1 more source

The Dirichlet Dual Response Model: An Item Response Model for Continuous Bounded Interval Responses. [PDF]

Psychometrika, 2023
Kloft M, Hartmann R, Voss A, Heck DW.
europepmc   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

A New Approach to Desirable Responding: Multidimensional Item Response Model of Overclaiming Data. [PDF]

Appl Psychol Meas, 2023
Jin KY, Paulhus DL, Shih CL.
europepmc   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

Analyzing the psychometric properties of the PHQ-9 using item response theory in a Chinese adolescent population

Annals of General Psychiatry
Background People are more likely to fall victim to depression during adolescence since it is a period of rapid biopsychosocial transformation. Despite this, most depression research has concentrated on clinical issues, and evaluating depressive symptoms
Xuliang Gao, Ziyu Liu
doaj   +1 more source