Results 71 to 80 of about 1,160,716 (327)

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

An empirical comparison of Item Response Theory and Classical Test Theory [PDF]

Psihološka Obzorja, 2008
Based on nonlinear models between the measured latent variable and the item response, item response theory (IRT) enables independent estimation of item and person parameters and local estimation of measurement error.
Špela Progar, Gregor Sočan
doaj  

Comparison of item analysis results of Korean Medical Licensing Examination according to classical test theory and item response theory [PDF]

Journal of Educational Evaluation for Health Professions, 2004
The results of the 64th and 65th Korean Medical Licensing Examination were analyzed according to the classical test theory and item response theory in order to know the possibility of applying item response theory to item analys and to suggest its ...
Eun Young Lim, Jang Hee Park, ll Kwon, Gue Lim Song, Sun Huh   +4 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Item Response Modeling of Multivariate Count Data With Zero Inflation, Maximum Inflation, and Heaping [PDF]

, 2017
Questionnaires that include items eliciting count responses are becoming increasingly common in psychology. This study proposes methodological techniques to overcome some of the challenges associated with analyzing multivariate item response data that ...
Brooke E. Magnus, Centers for Disease Control and Prevention, David Thissen, Thissen D., Thissen D., Wright D. E.   +5 more
core   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

A practical guide to item bank calibration with multiple matrix sampling

International Journal of Assessment Tools in Education
When it is required to estimate item parameters of a large item bank, Multiple Matrix Sampling (MMS) design provides an efficient way while minimizing the test burden on students. The current study exemplifies how to calibrate a large item pool using MMS
Güneş Ertaş, Serkan Arıkan, Eren Can Aybek   +2 more
doaj   +1 more source

Anchor methods for DIF detection: A comparison of the iterative forward, backward, constant and all-other anchor class [PDF]

, 2013
In the analysis of differential item functioning (DIF) using item response theory (IRT), a common metric is necessary to compare item parameters between groups of test-takers.
Kopf, Julia, Strobl, Carolin, Zeileis, Achim   +2 more
core   +1 more source