Results 81 to 90 of about 48,863 (239)
Deep and disseminated dermatophytosis in immunocompromised populations—A systematic review
Dermatophyte infections of the dermis and subcutaneous tissue (i.e. deep dermatophytosis)—associated with secondary complications including pseudomycetoma and systemic dissemination—affect vulnerable populations with primary or acquired immunodeficiencies.
Aditya K. Gupta +5 more
wiley +1 more source
ABSTRACT Objective Encephalitozoon pogonae, a recently identified microsporidian species, has been associated with systemic infections in Central bearded dragons (Pogona vitticeps) manifesting as granulomatous inflammation and vasculitis. Despite the species similarity to Encephalitozoon cuniculi, which causes ocular, neurologic, and renal pathology in
Vanessa Raphtis +6 more
wiley +1 more source
Itraconazole is a synthetic antifungal drug administered orally with a broad spectrum of activity against mycotic infections. The present work consists of the development and validation of analytical methodology for evaluation of itraconazole in ...
Edith Cristina Laignier Cazedey +3 more
doaj +1 more source
Physiologically based pharmacokinetic (PBPK) modeling for itraconazole using a bottom-up approach is challenging, not only due to complex saturable pharmacokinetics (PK) and the presence of three metabolites exhibiting CYP3A4 inhibition, but also because
Luna Prieto Garcia +5 more
semanticscholar +1 more source
Aims Spontaneous reporting of adverse drug reactions (ADR) after a product has reached the market is essential for drug safety. This study analysed patient ADR reports and compared them with reports from the Japanese Adverse Drug Event Report (JADER) database to identify differences and trends.
Masami Tsuchiya +5 more
wiley +1 more source
Pharmaceutical Compounding in Veterinary Medicine: Suspension of Itraconazole
Itraconazole is a drug used in veterinary medicine for the treatment of different varieties of dermatophytosis at doses between 3–5 mg/kg/day in cats. Nevertheless, in Spain, it is only available in the market as a 52 mL suspension at 10 mg/mL.
Gema J. Cabañero-Resta +6 more
doaj +1 more source
Potential adverse drug events can be signaled in Clinical Decision Support Systems (CDSSs). This study validated a Swedish CDSS (Janusmed Risk Profile) by investigating associations between calculated risk classifications of drugs with QT‐prolonging potential and registered related clinical outcomes.
Ola Nordqvist +6 more
wiley +1 more source
Itraconazole is a triazole antifungal given orally for the treatment of oropharyngeal and vulvovaginal candidiasis, for systemic infections including aspergillosis, candidiasis, and for the prophylaxis of fungal infections in immunocompromised patients.
Asmaa M. Rashid, Shaimaa N. Abdal-Hammid
doaj +1 more source

