Results 21 to 30 of about 7,739 (166)

Association between NT-proBNP and ivabradine in patients after noncardiac surgery: a per-protocol analysis of the PREVENT-MINS study [PDF]

open access: yesAnaesthesiology Intensive Therapy
Background The PREVENT-MINS trial investigated whether perioperative heart rate reduction with ivabradine could prevent myocardial injury after noncardiac surgery (MINS). Although ivabradine modestly reduced heart rate, it did not reduce the incidence of
Jacek Gorka   +22 more
doaj   +2 more sources

Effects of selective heart rate reduction with ivabradine on LV function and central hemodynamics in patients with chronic coronary syndrome

open access: yesInternational Journal of Cardiology: Heart & Vasculature, 2021
Objectives: We assessed left ventricular (LV) function and central hemodynamic effects in patients with a heart rate (HR) at rest of ≥70 beats per minute (bpm) and chronic coronary syndrome (CCS) after long-term treatment with ivabradine compared to ...
Anna Lena Hohneck   +8 more
doaj   +1 more source

Combination of ivabradine and sacubitril/valsartan in patients with heart failure and reduced ejection fraction

open access: yesESC Heart Failure, 2021
Aims Ivabradine and sacubitril/valsartan are second‐line therapies for patients with heart failure and reduced ejection fraction (HFrEF) based on guideline recommendations. We aimed to evaluate the synergistic effects of these two medications.
Ying‐Hsiang Lee   +9 more
doaj   +1 more source

Efficacy and Safety of Ivabradine Once-Daily Prolonged-Release versus Twice-Daily Immediate-Release Formulation in Patients with Stable Chronic Heart Failure with Systolic Dysfunction: A Randomized, Double-Blind, Phase 3 Non-Inferiority (PROFICIENT) Study

open access: yesCardiology and Therapy, 2020
Introduction Dosing frequency is an important factor influencing medication compliance in patients with heart failure (HF), which in turn is imperative in achieving the desired therapeutic outcome.
Ajit Mullasari   +1 more
doaj   +1 more source

Ivabradine monotherapy in congenital junctional ectopic tachycardia

open access: yes, 2022
Congenital JET (junctional ectopic tachycardia) is a rare and often difficult to treat tachyarrhythmia in young infants. The addition of Ivabradine to standard Congenital JET therapy has been shown to improve arrhythmia control.
Sivalingam Devaprasath   +3 more
core   +1 more source

The association between ivabradine and adverse cardiovascular events in acute decompensated HFrEF patients

open access: yesESC Heart Failure, 2021
Aims Ivabradine has been used in patients who have chronic heart failure (HF) with reduced ejection fraction (HFrEF) and concomitant sinus heart rate ≥70 bpm. This administration for acute HFrEF remains a concern. This study used a real‐world multicentre
Chia‐Te Liao   +9 more
doaj   +1 more source

A pilot study evaluating the role of ivabradine for rate control in patients with rheumatic atrial fibrillation

open access: yesIndian Heart Journal, 2023
Objectives: Ivabradine may have a role in rate control of atrial fibrillation (AF) due to effects on HCN channels in AV node. We studied role of Ivabradine in rate control of rheumatic AF. Methods: 80 patients, rheumatic AF, HR > 100 bpm (age 47 ± 11 yrs,
Arpita Katheria   +8 more
doaj   +1 more source

Heart rate and use of beta-blockers in stable outpatients with coronary artery disease [PDF]

open access: yes, 2012
<p><b>Background:</b> Heart rate (HR) is an emerging risk factor in coronary artery disease (CAD). However, there is little contemporary data regarding HR and the use of HR-lowering medications, particularly beta-blockers, among ...
Abergel, Helene   +66 more
core   +1 more source

An overview of ivabradine [PDF]

open access: yes, 2016
This article provides an overview of the therapeutic effects of ivabradine in the treatment of coronary artery disease (CAD), and in the management of stable angina pectoris (SAP) and congestive cardiac failure (CCF).
Bronkhorst, Elmien   +5 more
core   +1 more source

Locally injected ivabradine inhibits carrageenan-induced pain and inflammatory responses via hyperpolarization-activated cyclic nucleotide-gated (HCN) channels.

open access: yesPLoS ONE, 2019
BackgroundRecently, attention has been focused on the role of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in the mechanism of and as a treatment target for neuropathic and inflammatory pain.
Saki Miyake   +7 more
doaj   +1 more source

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