Results 71 to 80 of about 50,912 (262)

Lack of efficacy of standard doses of ivermectin in severe COVID-19 patients.

PLoS ONE, 2020
Ivermectin has recently shown efficacy against SARS-CoV-2 in-vitro. We retrospectively reviewed severe COVID-19 patients receiving standard doses of ivermectin and we compared clinical and microbiological outcomes with a similar group of patients not ...
Daniel Camprubí, Alex Almuedo-Riera, Helena Martí-Soler, Alex Soriano, Juan Carlos Hurtado, Carme Subirà, Berta Grau-Pujol, Alejandro Krolewiecki, Jose Muñoz   +8 more
doaj   +1 more source

Appraising the visibility, relevance and impacts of clinical pharmacology

British Journal of Clinical Pharmacology, Volume 91, Issue 7, Page 1884-1898, July 2025.
Aims Clinical pharmacology (CP) used to be a strong medical and scientific field, but during the last three decades it seems to have lost some of its appeal. We reviewed the visibility, relevance and impact of CP and clinical pharmacologists across the globe and suggest ways to strengthen the discipline to address future pharmacotherapeutic challenges.
Serge Cremers, Samuel L. M. Arnold, Nilima A. Kshirsagar, Catriona Waitt, Olayinka O. Ogunleye, Lars L. Gustafsson   +5 more
wiley   +1 more source

The Population Biology and Transmission Dynamics of Loa loa [PDF]

, 2017
Endemic to Central Africa, loiasis – or African eye worm (caused by the filarial nematode Loa loa) – affects more than 10 million people. Despite causing ocular and systemic symptoms, it has typically been considered a benign condition, only of public ...
Basáñez, M-G, Boussinesq, M, Chesnais, C B, Pion, S D S, Walker, M, Whittaker, C   +5 more
core   +1 more source

Poultry red mite eradication potential of ivermectin and allicin combination treatment

Veterinary Medicine and Science, 2023
Background Existing treatments against poultry red mite (PRM; Dermanyssus gallinae) infestation have reduced efficacy or exhibit hazardous effects on chickens.
JeongWoo Kang, HyunYoung Chae, Md Akil Hossain   +2 more
doaj   +1 more source

The Impact of Memory Effects on Lymphatic Filariasis Transmission Using Incidence Data From Ghana

Engineering Reports, Volume 7, Issue 7, July 2025.
Modeling Lymphatic Filariasis by incorporating disease awareness through fractional derivative operators. ABSTRACT Lymphatic filariasis is a neglected tropical disease caused by a parasitic worm transmitted to humans by a mosquito bite. In this study, a mathematical model is developed using the Caputo fractional operator.
Fredrick A. Wireko, Rebecca Awerigiya, Isaac K. Adu, Joshua N. Martey, Bernard O. Bainson, Joshua Kiddy K. Asamoah   +5 more
wiley   +1 more source

Contrasting sensitivities to toxicants of the freshwater amphipods Gammarus pulex and G. fossarum [PDF]

Amphipods are an important component of freshwater ecosystems. They are very often used in ecotoxicology, particularly the freshwater amphipod Gammarus pulex.
Alonso, A., Lange, H.J., de, Peeters, E.T.H.M.   +2 more
core   +2 more sources

Soil-transmitted helminth infections [PDF]

, 2018
More than a quarter of the world's population is at risk of infection with the soil-transmitted helminths Ascaris lumbricoides, hookworm (Ancylostoma duodenale and Necator americanus), Trichuris trichiura, and Strongyloides stercoralis. Infected children
Addiss, David G., Fenwick, Alan, Jourdan, Peter Mark, Lamberton, Poppy H.L.   +3 more
core   +1 more source

Apo‐state structure of the metabotropic glutamate receptor 5 transmembrane domain obtained using a photoswitchable ligand

Protein Science, Volume 34, Issue 7, July 2025.
Abstract Metabotropic glutamate receptor 5 (mGlu5) is implicated in various neurodegenerative disorders, making it an attractive drug target. Although several ligand‐bound crystal structures of mGlu5 exist, their apo‐state crystal structure remains unknown.
Yasushi Kondo, Caitlin Hatton, Robert Cheng, Matilde Trabuco, Hannah Glover, Quentin Bertrand, Fabienne Stierli, Hans‐Peter Seidel, Thomas Mason, Sivathmika Sarma, Friedjof Tellkamp, Michal Kepa, Florian Dworkowski, Pedram Mehrabi, Michael Hennig, Joerg Standfuss   +15 more
wiley   +1 more source

Identification of a novel ß-adrenergic octopamine receptor-like gene (ßAOR-like) and increased ATP-binding cassette B10 (ABCB10) expression in a Rhipicephalus microplus cell line derived from acaricide-resistant ticks [PDF]

, 2016
Background: The cattle tick Rhipicephalus (Boophilus) microplus is an economically important parasite of livestock. Effective control of ticks using acaricides is threatened by the emergence of resistance to many existing compounds. Several continuous R.
Bell-Sakyi, Lesley, Cooper, Katherine, Jonsson, Nicholas N., Koh-Tan, Han Hui, Strachan, Erin   +4 more
core   +1 more source

Field efficacy of a bioherbicide mimic (DiS‐NH2) in a nanoparticle formulation for weed control in durum wheat

Pest Management Science, Volume 81, Issue 7, Page 3796-3810, July 2025.
A new polymeric nanoparticle formulation containing aminophenoxazinone DiS‐NH2 (2,2′‐disulfanediyldianiline) is proposed as a post‐emergence and contact bioherbicide for weed management in durum wheat. Abstract BACKGROUND Weed‐resistance phenomena have increased dramatically in recent years. Bioherbicides can offer a sustainable alternative to chemical
Aurelio Scavo, Francisco J Rodríguez‐Mejías, Nuria Chinchilla, José MG Molinillo, Stefan Schwaiger, Alexander KH Weiss, Giovanni Mauromicale, Francisco A Macías   +7 more
wiley   +1 more source