Results 81 to 90 of about 66,840 (318)

Ivermectin reduces in vivo coronavirus infection in a mouse experimental model

Scientific Reports, 2021
The objective of this study was to test the effectiveness of ivermectin for the treatment of mouse hepatitis virus (MHV), a type 2 family RNA coronavirus similar to SARS-CoV-2.
A. Arévalo, R. Pagotto, J. Pórfido, H. Daghero, M. Segovia, K. Yamasaki, B. Varela, M. Hill, J. M. Verdes, M. Duhalde Vega, M. Bollati-Fogolín, M. Crispo   +11 more
semanticscholar   +1 more source

Discovery of murayaquinone from an endophytic bacterium Streptomyces sp. AN140557 as a potent inhibitor of the pine wood nematode, Bursaphelenchus xylophilus

Pest Management Science, EarlyView.
Murayaquinone isolated from the pine endophyte Streptomyces sp. AN140557 exhibits potent, dose‐dependent nematicidal activity and egg‐hatching inhibition against the pine wood nematode. It effectively inhibited pine wilt disease in greenhouse tests, suggesting potential as a promising biocontrol agent.
Min‐Kyoung Kang, Hyeon‐Ji Kim, Jong‐Hoon Kim   +2 more
wiley   +1 more source

Pharmacokinetics, safety, and efficacy of a single co-administered dose of diethylcarbamazine, albendazole and ivermectin in adults with and without Wuchereria bancrofti infection in Cote d\u27Ivoire [PDF]

, 2019
BackgroundA single co-administered dose of ivermectin (IVM) plus diethylcarbamazine (DEC) plus albendazole (ALB), or triple-drug therapy, was recently found to be more effective for clearing microfilariae (Mf) than standard DEC plus ALB currently used ...
Bjerum, Catherine M, Chhonker, Yashpal S, Edi, Constant, King, Christopher L, Koudou, Benjamin G, Meite, Aboulaye, Murry, Daryl J, Ouattara, Allassane F, Penali, Louis K, Weil, Gary J   +9 more
core   +4 more sources

Advancing pharmacometrics in Africa—Transition from capacity development toward job creation

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai, Samer Mouksassi, Innocent G. Asiimwe, Craig R. Rayner, Steven Kern, Phumla Sinxadi, Paolo Denti, Eric Decloedt, Catriona Waitt, Bernhards R. Ogutu, Rik de Greef   +10 more
wiley   +1 more source

Complexin in ivermectin resistance in body lice. [PDF]

PLoS Genetics, 2018
Ivermectin has emerged as very promising pediculicide, particularly in cases of resistance to commonly used pediculicides. Recently, however, the first field-evolved ivermectin-resistance in lice was reported.
Nadia Amanzougaghene, Florence Fenollar, Claude Nappez, Amira Ben-Amara, Philippe Decloquement, Said Azza, Yassina Bechah, Eric Chabrière, Didier Raoult, Oleg Mediannikov   +9 more
doaj   +1 more source

Evidence-based indications for ivermectin in parasitic diseases: An integrated approach to context and challenges in Peru

Parasite Epidemiology and Control, 2023
Ivermectin has emerged as a therapeutic option for various parasitic diseases, including strongyloidiasis, scabies, lice infestations, gnathostomiasis, and myiasis.
Virgilio E. Failoc-Rojas, Heber Silva-Díaz, Jorge L. Maguiña, Alfonso J. Rodriguez-Morales, Cristian Díaz-Velez, Moises Apolaya-Segura, Mario J. Valladares-Garrido   +6 more
doaj   +1 more source

Increased expression of a microRNA correlates with anthelmintic resistance in parasitic nematodes [PDF]

, 2017
Resistance to anthelmintic drugs is a major problem in the global fight against parasitic nematodes infecting humans and animals. While previous studies have identified mutations in drug target genes in resistant parasites, changes in the expression ...
Bartley, David, Britton, Collette, Devaney, Eileen, Gillan, Victoria, Gilleard, John S., Gu, Henry, Laing, Roz, Maitland, Kirsty, Marks, Neil D., Martinelli, Axel, Morrison, Alison, Rezansoff, Andrew M., Skuce, Philip J., Winter, Alan D.   +13 more
core   +2 more sources

A Comparative Study on Ivermectin-Doxycycline and Hydroxychloroquine-Azithromycin Therapy on COVID-19 Patients

Eurasian Journal of Medicine and Oncology, 2021
Objectives: We investigated the outcomes of Ivermectin-Doxycycline vs Hydroxychloroquine-Azithromycin combination therapy in mild to moderate COVID19 patients Methods: Patients were divided randomly into two groups: Ivermectin 200 mu gm/kg single dose ...
A. Chowdhury, Mohammad Shahbaz, Md Rezaul Karim, Jahirul Islam, G. Dan, He Shuixiang   +5 more
semanticscholar   +1 more source

Body condition score and weight are effective targeted selective treatment indicators for gastrointestinal nematodes in premating ewes

Veterinary Record, EarlyView.
Abstract Background Ewe reproductive performance is key for flock profitability but can be impacted upon by gastrointestinal nematode (GIN) infections. Farmers commonly deworm ewes pre‐mating, yet concerns regarding anthelmintic resistance increase pressure to reduce wormer use.
Eiry G. Williams, Peter M. Brophy, Hefin W. Williams, Serian R. Evans, Heather McCalman, Rhys A. Jones   +5 more
wiley   +1 more source

Poultry red mite eradication potential of ivermectin and allicin combination treatment

Veterinary Medicine and Science, 2023
Background Existing treatments against poultry red mite (PRM; Dermanyssus gallinae) infestation have reduced efficacy or exhibit hazardous effects on chickens.
JeongWoo Kang, HyunYoung Chae, Md Akil Hossain   +2 more
doaj   +1 more source