Results 261 to 270 of about 73,607 (303)

Sorghum Promotes Cell Proliferation Through Activation of the Growth Hormone/IGF-1-JAK2/STAT5b Signaling Axis <i>In Vitro</i>. [PDF]

Biology (Basel)
Park S, Kang DY, Kim HT, Shin WS, Lee S, Cho J, Jang KJ.   +6 more
europepmc   +1 more source

Aging changes the mechanism that underlies JAK2 modulation of neutrophil function. [PDF]

J Immunol
Feldmann JW, Kays M, McGinnis F, Herron E, Sati N, Woods C, Coulibaly AP.   +6 more
europepmc   +1 more source

Development Trends of Janus Kinase Inhibitors (JAKi) Over Three Decades: From Common to Rare Diseases. [PDF]

Drug Des Devel Ther
Dai R, Lou N, Zheng X, Han X.
europepmc   +1 more source

Polycythemia Vera with Incidental Large Aortic Aneurysm and Giant Cell Arteritis: Case Report. [PDF]

Clin Med Insights Case Rep
Obaid K, Sadek K, Al Jaber F, Altermanini M, Al-Mashdali AF, Yassin M, Alkhulaifi AM, Carr CS, Mohamed SF.   +8 more
europepmc   +1 more source

Toward new therapy end points in polycythemia vera: targeting clonal and inflammatory pathways. [PDF]

Blood Adv
Barbui T, Scandura JM.
europepmc   +1 more source

Late Onset Telomere Biology Disorder Presenting With Pancytopenia, Immune Dysregulation, Interstitial Lung Disease and Alopecia

American Journal of Hematology, Volume 101, Issue 6, Page 1196-1200, June 2026.
Bo A. Wan, Hamish Nicolson, Heather A. Leitch, Ryan J. Stubbins, Luke Y. C. Chen, Timothy Murray, Amy Trottier, Anthony Gador   +7 more
wiley   +1 more source

JAK2 and myeloproliferative neoplasms

, 2013
openaire   +1 more source

JAK2, the JAK2 V617F mutant and cytokine receptors

Pathologie Biologie, 2007
Recently, a unique recurrent somatic mutation was identified as a major molecular event in polycythemia vera, essential thrombocythemia and idiopathic myelofibrosis. Expression of this mutant in cytokine-dependent hematopoietic cell lines induces autonomous growth. This effect is enhanced by overexpression of cytokine receptors, and can be inhibited by
J, Staerk, A, Kallin, Y, Royer, C C, Diaconu, A, Dusa, J-B, Demoulin, W, Vainchenker, S N, Constantinescu   +7 more
openaire   +3 more sources

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JAK2-mediated Intracellular Signaling

Current Molecular Medicine, 2021
Janus kinase-2 (JAK2) is a non-receptor tyrosine kinase that serves key roles as the intracellular signaling effector of the cytokine receptor, such as mediating effects of leptin, erythropoietin, interferon, and growth hormone. A lot of molecular underlying mechanisms of JAK2 participation are known, however, additional signaling mechanisms of its ...
Mentor Sopjani, Valdet Uka, Nguyen Thi Xuan   +2 more
exaly   +3 more sources