Results 71 to 80 of about 5,550 (180)

The V617F mutation of JAK2 is very uncommon in patients with thrombosis

Haematologica, 2007
Given that many cases of thrombosis do not have a clear cause, a myeloproliferative disease could be involved. We investigated the V617F mutation of the JAK2 gene in 295 patients with thrombosis. Only one case was positive. Therefore, the study of this mutation is not necessary in all patients with idiopathic thrombosis.
Angel F. Remacha, Camino Estivill, M. Pilar Sarda, José Mateo, Joan Carles Souto, Carme Canals, Josep Nomdedéu, Jordi Fontcuberta   +7 more
openaire   +3 more sources

Carotid artery stenting in JAK2 V617F-positive essential thrombocythemia with symptomatic internal carotid artery stenosis: a case report

Frontiers in Cardiovascular Medicine
Essential thrombocythemia (ET) is a myeloproliferative neoplasm (MPN) characterized by abnormal megakaryocyte proliferation and a markedly elevated platelet count, which predisposes patients to thrombotic or hemorrhagic events.
Minghui Du, Minghui Du, Yinbao Hu, Zhigang Liang, Zhigang Liang, Zhigang Liang   +5 more
doaj   +1 more source

Influence of the JAK2 V617F mutation and inherited thrombophilia on the thrombotic risk among patients with essential thrombocythemia

Haematologica, 2009
It is uncertain whether the JAK2 V617F mutation increases the thrombotic risk in patients with essential thrombocythemia, and it is unknown whether inherited thrombophilia is an additive risk factor in mutated subjects.
Valerio De Stefano, Tommaso Za, Elena Rossi, Alessia Fiorini, Angela Ciminello, Claudia Luzzi, Patrizia Chiusolo, Simona Sica, Giuseppe Leone   +8 more
doaj   +1 more source

The bidirectional relationship between JAK2V617F allele burden and inflammation in polycythaemia vera: Insights from interferon and ruxolitinib therapy

HemaSphere, Volume 10, Issue 8, August 2026.
Tiziano Barbui, Paola Guglielmelli, Alessandro Maria Vannucchi   +2 more
wiley   +1 more source

Acute Finger Ischemia Evaluated With Point‐Of‐Care‐Ultrasound and Diagnosed With Concurrent Polycythemia Vera, Antiphospholipid Syndrome, and Tobacco Use

Clinical Case Reports, Volume 14, Issue 6, June 2026.
We present a case of digital ischemia investigated and localized using point‐of‐care ultrasound (POCUS), in a patient that was subsrquently diagnosed with antiphospholipid syndrome and polycythemia vera concurrently, in the setting of active tobacco use. ABSTRACT In patients with undifferentiated extremity ischemia, point‐of‐care ultrasound (POCUS) can
Tristan Burgess, Michael C. Larkins, Titus Chu   +2 more
wiley   +1 more source

Janus kinase 2 mutations in cases with BCR-ABL-negative chronic myeloproliferative disorders from Turkey

Avicenna Journal of Medicine, 2017
Objective: We aimed to investigate the frequency of Janus kinase 2 ( JAK2) mutations in cases with chronic myeloproliferative disorders (CMDs), and the relationship between the presence of JAK2 mutation and leukocytosis and splenomegaly, retrospectively.
Ismail Yildiz, Osman Yokuş, Habip Gedik
doaj   +1 more source

Detection of the Janus kinase 2 V617F mutation using a locked nucleic-acid, real-time polymerase chain reaction assay

African Journal of Laboratory Medicine, 2018
The purpose of this study was to develop a real time polymerase chain reaction (PCR) assay for the detection of the JAK2 V617F mutation that could be used in diagnostic laboratories.
Tshiphiri Senamela, Marleen Kock, Piet Becker, Joachim J.C. Potgieter   +3 more
doaj   +1 more source

The JAK2 V617F mutation in retinal vein or artery occlusion

EXCLI journal, 2019
EXCLI Journal;Vol.
openaire   +3 more sources

The Pattern of Thrombosis in Patients with JAK2 V617F Mutation

Journal of Blood Disorders, 2023
Background: JAK2V617F mutation is recurrent in MPN and reported as a marker for occult MPN in patients with splanchnic vein thrombosis. Objective: To better estimate the pattern of arterial and venous thrombosis in a Lebanese series in order to define the potential risk and to evaluate the current treatment.
openaire   +1 more source

A novel JAK1 variant in chronic eosinophilic leukaemia with response to benralizumab

British Journal of Haematology, Volume 209, Issue 1, Page 335-339, July 2026.
Isabel C. Vallecillo‐Viejo, Michael D. Claiborne, Charles F. Anderson, Samantha Shafer, Alan Saven, Bryce A. Seifert, Morgan Similuk, Magdalena Walkiewicz, Irina Maric, Pia R. Crespo, Lori Broderick, Andrew A. White, Amy D. Klion   +12 more
wiley   +1 more source