Results 61 to 70 of about 1,320,130 (285)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

A mini review on the Lactic Acidosis in goats and its remedial approaches

Aceh Journal of Animal Science, 2020
The current study was performed in order to investigate the threat of lactic acidosis in goats worldwide and explore the curative strategies. In this regards a detailed review was performed, however obtained facts were found to be much interesting and ...
Asad Ali Khaskheli, Muhammad Ibrahim Khaskheli, Allah Jurio Khaskheli, Arshad Ali Khaskheli   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The efficacy of mindfulness-based stress reduction program on disease perception in thalassemia patients

مجله علوم روانشناختی, 2022
Background: Disease perception is an organized cognitive representation that thalassemia patients have of their illness and its effects. Research has shown that mindfulness-based stress reduction programs are effective on self-management and reducing ...
Fatemeh Akbari Gelvardi, Saeed Teimory, Alireza Rajaei   +2 more
doaj  

RETRACTED ARTICLE Fuzzy multicriteria analysis of “Better Cotton” farmers’ adoption and experts’ recommendation on cotton pest and disease management practices

Spanish Journal of Agricultural Research, 2022
RETRACTATION The SJAR Editorial Board, following the Guide to Good Practices of Editorial CSIC and the international recommendations of editorial ethics, due to a conflict of duplicity, has agreed to formally retract the following article: Fuzzy ...
Absar M. Jiskani, Manzoor A. Abro, M. Ibrahim Khaskheli, Khadim H. Wagan   +3 more
doaj   +1 more source

Elevated expression of JAM‐A promotes neoplastic properties of lung adenocarcinoma

Cancer Science, 2017
A cell–cell adhesion protein, junctional adhesion molecule‐A (JAM‐A), has been shown to be involved in neoplasia of various organs. However, the fundamental role of JAM‐A in tumorigenesis is still under debate because dysregulated expression of this ...
Kazufumi Magara, A. Takasawa, M. Osanai, Misaki Ota, Y. Tagami, Yusuke Ono, Kumi Takasawa, M. Murata, Y. Hirohashi, M. Miyajima, G. Yamada, T. Hasegawa, N. Sawada   +12 more
semanticscholar   +1 more source

Ice-Cover and Jamming Effects on Inline Structures and Upstream Water Levels

, 2017
River ice cover is a reoccurring phenomenon in the Northern United States every year. Sheets and layers of ice result in a rise of water surface elevation and may lead to ice jams in a river.
Ahmad, Sajjad, Bhandari, Swastik, Jobe, Addison, Kalra, Ajay   +3 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Correction to: Effectiveness of Self-Management Training Based on Group Cognitive Behavioral Therapy on Quality of Life in Adults with Metabolic Syndrome: A Randomized Clinical Trial

Journal of Mazandaran University of Medical Sciences, 2021
In the article published in volume 31, issue 197, 2021, the affiliation of Ali Delshad Noghabi was published incorrectly, which is now corrected. Also, the name of Fatemeh Mohammadzadeh was removed from the list of authors.
Ali Delshad Noghabi, Mohammad Hossein Bayazi, Alireza Rajaei   +2 more
doaj  

JAM: A Scalable Bayesian Framework for Joint Analysis of Marginal SNP Effects

Genetic Epidemiology, 2016
Recently, large scale genome‐wide association study (GWAS) meta‐analyses have boosted the number of known signals for some traits into the tens and hundreds. Typically, however, variants are only analysed one‐at‐a‐time.
P. Newcombe, D. Conti, S. Richardson
semanticscholar   +1 more source