The Relationship Between Janus Kinase Pathways and MicroRNAs [PDF]
, 2017 Janus Kinase (JAK) family is a group of four signaling enzymes composing of four distinct domains and involved in the intracellular pathways of cytokine downstream signaling.
Tabarzad, Maryam +4 more
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Revisiting Janus Kinase Inhibitors in Hospitalized COVID-19: Evidence for Baricitinib’s Superiority and the Absence of a Class Effect [PDF]
Lei Gu,1,* Jing Lin,2,* Jian Yue,3,* Zeyi Liu,1 Jian-an Huang1 1Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, People’s Republic of China; 2Department of ...
Liu Z, Gu L, Lin J, Huang JA, Yue J
core
Hyperlipidaemic effect of Janus kinase inhibitors: a meta-analysis [PDF]
, 2019 Introduction: Janus kinase (JAK) inhibitors are effective in treating rheumatoid arthritis. However, JAK is involved in lipid metabolism, so we investigated the association between JAK inhibitors and hyperlipidaemia.
Tsoi, MF, Cheung, TT, Cheung, BMY
core
Negative patch test findings after initiation of upadacitinib: A case report
SAGE Open Medical Case ReportsUpadacitinib is a systemic Janus kinase inhibitor currently approved for the treatment of atopic dermatitis. Many patients with atopic dermatitis have a concomitant diagnosis of allergic contact dermatitis.
Meghan L McPhie +2 more
doaj +1 more source
Adenosine-Stimulated Adrenal Steroidogenesis Involves the Adenosine a(2a) and a(2b) Receptors and the Janus Kinase 2-Mitogen-Activated Protein Kinase Kinase-Extracellular Signal-Regulated Kinase Signaling Pathway [PDF]
, 2009 Adenosine promotes adrenal steroidogenesis in vitro and in vivo. However, the underlying signaling mechanisms of this event and the function of the adenosine receptor subtypes in adrenal cells remain to be elucidated. Expression of A(1), A(2A), A(2B) and
CHEN, YUNG-CHIA;HUANG, SHIH-HORNG;WANG, SEU-MEI +1 more
core
Modern Management Approaches for Alopecia Areata
Вопросы современной педиатрииAlopecia areata is a chronic genetically determined inflammatory autoimmune disease damaging hair follicles and leading to temporary or persistent nonscarring hair loss.
Eduard T. Ambarchyan +4 more
doaj +1 more source
Targeting upstream Janus kinases [PDF]
, 2016 Targeting upstream Janus ...
Parisa Rasighaemi (13532374) +1 more
core
Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy
Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley +1 more source
International Journal of Cancer, EarlyView.ABSTRACT The recently published ONKOPEDIA guideline on myelofibrosis, issued under the auspices of the German Society of Hematology and Oncology (DGHO), provides an updated, evidence‐based framework for the diagnosis and management of this rare, chronic myeloproliferative neoplasm.
Martin Griesshammer +8 more
wiley +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective To investigate the role of ST3 β‐galactoside α‐2,3‐sialyltransferase 1 (ST3Gal1) and vascular endothelial growth factor receptor 2 (VEGF‐R2) in endometrioid‐type epithelial ovarian cancer (E‐OC) because aberrant α2,3‐sialylation mediated by ST3Gal1 and VEGF‐R2‐related angiogenesis is linked with tumor progression. Methods ST3Gal1 and
Wei‐Ting Chao +5 more
wiley +1 more source