Results 71 to 80 of about 246,780 (358)
The human neurotropic virus JC Polyomavirus, a member of the Polyomaviridae family, is the opportunistic infectious agent causing progressive multifocal leukoencephalopathy, typically in immunocompromised individuals.
Vijay Harypursat+3 more
doaj +1 more source
This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle+9 more
wiley +1 more source
Jc Virus-Induced Progressive Multifocal Leukoencephalopathy [PDF]
Progressive multifocal encephalopathy (PML) is a fatal demyelinating disease of the central nervous system (CNS), caused by the lytic infection of oligodendrocytes by a human polyomavirus, JC virus (JCV). PML is rare disease but mostly develops in patients with underlying immunosuppressive conditions, including Hodgkin's lymphoma, lymphoproliferative ...
Cathy Lam+3 more
openaire +3 more sources
Correlative super‐resolution optical imaging of the ultrastructure of rat liver sinusoidal endothelial cells (LSECs) across a large field of view (FOV) with 3D structured illumination microscopy (3D‐SIM) and single‐molecule localization microscopy (SMLM), facilitated by a transparent polymer photonic waveguide chip, is presented.
Surjendu Bikash Dutta+9 more
wiley +1 more source
Advanced Virus Monitoring and Analysis System [PDF]
This research proposed an architecture and a system which able to monitor the virus behavior and classify them as a traditional or polymorphic virus. Preliminary research was conducted to get the current virus behavior and to find the certain parameters which usually used by virus to attack the computer target.
arxiv
Progressive Multifocal Leukoencephalopathy Associated to Multiple Sclerosis Therapies: Review of the literature [PDF]
Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection associated with the reactivation of the JC virus, causing a severe demyelination within the central nervous system in patients with immunosuppression caused by disease or ...
Ana-Maria Vladila+3 more
doaj +1 more source
The DNA damage response promotes Polyomavirus JC infection by nucleus to cytoplasm NF-Kappa B activation. [PDF]
Background: Infection of glial cells by human neurotropic polyomavirus JC (JCV), the causative agent of the CNS demyelinating disease progressive multifocal leukoencephalopathy (PML), rapidly inflicts damage to cellular DNA.
Bellizzi, Anna+5 more
core +1 more source
Anti-JC virus seroprevalence in a Spanish multiple sclerosis cohort
To estimate the seroprevalence of anti-JCV antibodies, seroconverting rates and evolution of antibody levels in a multiple sclerosis (MS) Spanish cohort.Multicenter, retrospective cross-sectional and longitudinal study. The JCV seroprevalence was analyzed in 711 MS patients by using 1st (STRATIFY-1) and 2nd generation (STRATIFY-2) two-step ELISA over 2.
Yolanda Aladro+22 more
openaire +5 more sources
Modern Strategies in Wound Healing: The Rise of Bacterial Cellulose Dressings
Bacterial cellulose (BC)‐based wound dressings combine high water retention, biocompatibility, and mechanical strength to support wound healing. This review highlights advanced functionalization strategies and fabrication techniques that enhance BC's therapeutic performance, establishing it as a promising material for next‐generation wound care ...
Elif Naz Gürsoy+4 more
wiley +1 more source
Lecithin Alleviates Memory Deficits and Muscle Attenuation in Chinese Older Adults and SAMP8 Mice
This study opens a new avenue for safeguarding cognition and muscle health, averting disability in older age, and treating age‐related pathologies through lecithin supplementation. It serves as a promising nonpharmacological intervention for the crosstalk of muscle and cognition.
Xianyun Wang+16 more
wiley +1 more source