Results 71 to 80 of about 2,027,813 (387)

JC Virus: An oncogenic virus in animals and humans? [PDF]

Seminars in Cancer Biology, 2009
JC virus (JCV) is a human polyomavirus of the Polyomaviridae family, which also includes BK virus and simian vacuolating virus 40 (SV40). JC virus was first isolated in 1971 from the brain of a patient with Progressive Multifocal Leukoencephalopathy (PML). Like other polyomaviruses, JCV has a restricted host range. The virus infects the majority of the
Melissa S, Maginnis, Walter J, Atwood
openaire   +2 more sources

JC Polyomavirus-Associated Nephropathy Case Report: Clinical and Laboratory Learning

British Journal of Biomedical Science
IntroductionJohn Cunningham (JC) virus is commonly associated with progressive multifocal leukoencephalopathy. However, this polyomavirus can also be a rare etiological agent of nephropathy in renal transplant recipients.
Rachael M. Tomb, Siobhan K. McManus, David Kipgen, Sawsan Yaqub, Sally Taylor, Rory N. Gunson   +5 more
doaj   +1 more source

A fulminant case of JC virus encephalopathy supporting a novel syndrome associated with JC virus infection of cortical neurons [PDF]

Journal of Health and Social Sciences, 2016
The JC virus ( JCV) is well known for causing progressive multifocal leukoencephalopathy (PML), a potentially fatal, demyelinating disease of the central nervous system (CNS).
Matteo Ciocca, Marta Pirovano, Monica Lodi, Antonino Romeo, Vincenza Fetoni   +4 more
doaj   +1 more source

A programme for risk assessment and minimisation of progressive multifocal leukoencephalopathy developed for vedolizumab clinical trials [PDF]

, 2018
Introduction Over the past decade, the potential for drug-associated progressive multifocal leukoencephalopathy (PML) has become an increasingly important consideration in certain drug development programmes, particularly those of immunomodulatory ...
Berger, Joseph R, Clifford, David B, Fox, Irving, Lev, Michael H, Major, Eugene, McAuliffe, Megan, Milch, Catherine, Parikh, Asit, Patti, Mark, Provenzale, James M, Sankoh, Serap, Shick, Jesse, Stephens, Kristin   +12 more
core   +3 more sources

Progressive multifocal leukoencephalopathy and immune reconstitution inflammatory syndrome in seven patients with sarcoidosis: a critical discussion of treatment and prognosis

Therapeutic Advances in Neurological Disorders, 2021
Progressive multifocal leukoencephalopathy (PML) is a subacute brain infection by the opportunistic John Cunningham (JC) virus. Herein, we describe seven patients with PML, lymphopenia, and sarcoidosis, in three of whom PML was the first manifestation of
Maike F. Dohrn, Gisa Ellrichmann, Rastislav Pjontek, Carsten Lukas, Jens Panse, Ralf Gold, Jörg B. Schulz, Burkhard Gess, Simone C. Tauber   +8 more
doaj   +1 more source

Anti‐JC virus seroprevalence in a Finnish MS cohort

Acta Neurologica Scandinavica, 2016
The risk of progressive multifocal leukoencephalopathy (PML) caused by the JC virus (JCV) is increased in patients with multiple sclerosis receiving biological therapies.
Marcin Kolasa, S. Hagman, A. Verkkoniemi-Ahola, L. Airas, Keijo Koivisto, Irina Elovaara   +5 more
semanticscholar   +1 more source

Progressive multifocal leukoencephalopathy in the clinical practice of a neurologist. Case report [PDF]

Consilium Medicum
Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection with severe brain damage caused by the JC-virus, against the background of immunosuppressive conditions.
Yuliana A. Belova, Sergey V. Kotov
doaj   +1 more source

VALIDAÇÃO DO MÉTODO PCR EM TEMPO REAL PARA DIAGNÓSTICO DE CITOMEGALOVÍRUS E DOS POLIOMAVÍRUS BK E JC EM AMOSTRAS DE PACIENTES TRANSPLANTADOS RENAIS

Hematology, Transfusion and Cell Therapy, 2023
Introdução e objetivo: Os poliomavírus e citomegalovírus são vírus ubíquos na população que permanecem latentes em vários tecidos de indivíduos portadores.
MLMV Corgozinho, S Vilaça, A França, AGG Oliveira, LV Alves, JKPD Reis, BEF Mota, APL Mota   +7 more
doaj   +1 more source

Advances in the design and development of oncolytic measles viruses. [PDF]

, 2015
A successful oncolytic virus is one that selectively propagates and destroys cancerous tissue without causing excessive damage to the normal surrounding tissue. Oncolytic measles virus (MV) is one such virus that exhibits this characteristic and thus has
Hutzen, Brian, Raffel, Corey, Studebaker, Adam W   +2 more
core   +1 more source

In Vivo siRNA Delivery Using JC Virus-like Particles Decreases the Expression of RANKL in Rats

Molecular Therapy: Nucleic Acids, 2016
Bone remodeling requires a precise balance between formation and resorption. This complex process involves numerous factors that orchestrate a multitude of biochemical events.
D. Hoffmann, K. Böker, S. Schneider, Ellen Eckermann-Felkl, Angelina Schuder, M. Komrakova, S. Sehmisch, Jens Gruber   +7 more
semanticscholar   +1 more source