Results 91 to 100 of about 65,609 (259)

Comparison of Receptor‐Mediated Endocytosis and Its Application to Enhance DNA Transfection by TFAMoplex

Advanced NanoBiomed Research, EarlyView.
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer, Steffen Honrath, Jonas Kurmann, Alexander Klipp, Finn Brigger, Jean‐Christophe Leroux   +5 more
wiley   +1 more source

In ovo Antiviral Screening of Four Nigerian Medicinal Plants (Artemisia absinthium L., Annona senegalensis Pers., Erythrina senegalensis DC., and Jatropha curcas L.) Against Newcastle Disease Virus [PDF]

Journal of Shahrekord University of Medical Sciences
Background and aims: Newcastle disease virus (NDV) poses a major threat to global poultry production, driving interest in novel plant-based antiviral agents.
Sylvester Nefai Mathias, Emmanuel Halilu Mshelia, Chinenye Jane Ugwah-Oguejiofor, Ibrahim Yusuf Alkali, Aminu Ahmed Biambo, Mansur Lawal, Aliyu Hamidu Ahmed   +6 more
doaj   +1 more source

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

Animal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang, Tianqi Jin, Zexin Chen, Ye Gong, Qimin Liu, Zifang Wu, Heran Cao, Yan Li, Yuyan Liu, Tianhao Yang, Zhihong Jiang, Wuzi Dong   +11 more
wiley   +1 more source

Opposing consensus science through scholarly practices: The role of claims maintenance

Journal of the Association for Information Science and Technology, EarlyView.
Abstract This study examines how three US‐based communities who oppose consensus science produce and disseminate scholarly‐like artifacts: pro‐life activists, Young Earth Creationists, and Anthropogenic Climate Crisis skeptics. Prior research shows that industry‐ or church‐backed advocacy campaigns often generate claims supported by these communities ...
Irene V. Pasquetto, Morgan Wofford, Claire Jordan, Andrea Thomer   +3 more
wiley   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

The impact of JC viruria on renal transplant recovery and prognosis

Scientific Reports
Postoperative JC viruria is common in kidney transplant recipients, however there remains a dearth of research on perioperative JCV infection in this population. The clinical significance of JCV monitoring in kidney transplant recipients remains unclear.
Zehua Zhang, Yuxiong Wang, Baoshan Gao, Bin Liu, Jinyu Yu, Honglan Zhou   +5 more
doaj   +1 more source

Efficacy of filgrastim therapy for patients with progressive multifocal leukoencephalopathy: Two case reports

International Journal of Infectious Diseases
Progressive multifocal leukoencephalopathy (PML) is a life-threatening central nervous system condition caused by reactivation of JC virus in individuals with immunosuppression.
Hanako Aoki, Ryunosuke Matsumura, Yoichiro Nishida, Kazuo Nakamichi, Takanori Yokota, Nobuo Sanjo   +5 more
doaj   +1 more source

Deep brain stimulation of the thalamus for intractable epilepsy (FRANCE study): A randomized clinical trial

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate the efficacy and safety of deep brain stimulation (DBS) of the anterior nucleus of the thalamus (ANT) compared with best medical treatment (BMT) in patients with drug‐resistant epilepsy (DRE).
Stéphan Chabardès, Fabrice Bartolomei, Anca Nica, Claire Haegelen, Lorella Minotti, Brigitte Piallat, Chrystele Mosca, Sandrine Massicot, Sylvain Rheims, Marc Guenot, Emmanuel Cuny, Jérome Aupy, Louis Maillard, Sophie Colnat‐Coulbois, Corentin Leroy, Romain Carron, Philippe Coubes, Philippe Gélisse, Carine Karachi, Vincent Navarro, Bertrand Devaux, Francine Chassoux, Phlippe Derambure, Nicolas Reyns, Jean Christope Sol, Luc Valton, Denys Fontaine, Veronique Bourg, Philippe Kahane, Sandra David‐Tchouda, Jean Regis   +30 more
wiley   +1 more source

Health System Factors in Head and Neck Cancer Diagnosis: A HEADSpAcE Consortium Qualitative Study in Glasgow and Montevideo

Head &Neck, EarlyView.
ABSTRACT Background Head and neck cancer (HNC) is a devastating diagnosis, with advanced‐stage disease leading to poorer outcomes. This qualitative study aimed to identify health system factors associated with stage of HNC diagnosis. Methods Qualitative semistructured interviews with HNC patients and clinicians were undertaken in two purposively ...
Grant Creaney, Iván Lyra González, Mauricio Cuello, Mariél de Aquino Goulart, Alex D. McMahon, Claire Paterson, James McCaul, Maja Popovic, Lorenzo Richiardi, Silvia Lopez de Blanc, Maria Paula Curado, Marta Vilensky, HEADSpAcE Consortium, Elmira Ebrahimi, Apiwat Sangphukieo, Hanla A Park, Valerie Gaborieau, Wolfgang Ahrens, Laia Alemany, Lidia MRB Arantes, Jaroslav Betka, Cristina Canova, David I Conway, Mauricio Cuello, Maria Paula Curado, Ana Carolina de Carvalho, Jose Carlos de Oliviera, Mark Gormley, Maryam Hadji, Claire M Healy, Ivana Holcatova, Luis P Kowalski, Pagona Lagiou, Areti Lagiou, Gary J Macfarlane, Sandra Perdomo, Luis Felipe Ribiero Pinto, Jose Roberto V Podesta, Jerry Polesel, Miranda Pring, Hamideh Rashidian, Ricardo R Gama, Lorenzo Richiardi, Max Robinson, Paula A Rodriguez‐Urrego, Sheila C Soares‐Lima, Nicolas Timpson, Marta Vilensky, Sandra V von Zeidler, Tim Waterboer, Kazem Zendehdel, Ariana Znaor, Paul Brennan, James McKay, Shama Virani, Tom Dudding, Roque Adam, Antonio Agudo, Shaymaa F AlWaheidi, Miquel Angel Pavon, Namrah Anwar, Paola Engelmann Arantes, Lisa Arguello, Yubelly Avello, Lucas Avondet, Ana M Baldión‐Elorza, Camila Batista Daniel, Bianca Beraldi, Barbara Berenstein, Patricia Bernal, Natália Bernardino Rodrigues, Josipa Bilic Zimmermann, Marianna G Botta, Jesús Brenes, Nicole Brenner, Carol Brentisci, Catalina Burtica, María L Cabañas, Erick Cantor, Raiany S Carvalho, Andre L Carvalho, Luigi Chiusa, Priscilia Chopard, Qurratulain Chundriger, Omar Clavero, Isabela Costa, Grant Creaney, Cecilia Cuffini, Tauana C Dias, Evandro Duccini de Souza, Lais C Durant, Alberto Escallón, Gisele Aparecida Fernandes, Béatrice Fervers, Valentina Fiano, Frederico Firme Figueira, Regina Furbino Villefort, Manuela Gangemi, Paolo Garzino‐Demo, Mahin Gholipour, Raul Giglio, Mariel A Goulart, Jéssica Graça Sant'Anna, Marek Grega, Anna Clara Gregório Có, Arnau Guasch, Jose A Hakim, David N Hayes, Marco Homero de Sá Santos, Katrina Hurley, Magalí Insfran, Giuseppe C Iorio, Moghira Iqbaluddin Siddiqui, Jannik Johannsen, Martin Kaňa, Jens Peter Klussmann, Evelio Legal, Jeferson Lenzi, Fernando Luiz Dias, Iván Lyra González, Willene Machado Zorzaneli, Ricardo Mai Rocha, Manel Mañós, Priscila Marinho de Abreu, Maryam Marzban, James McCaul, Alex D. McMahon, Carlos Mena, Elismauro F Mendonça, Laura Mendoza, Lorena Meza, Birgitta Michels, Matinair S Mineiro, Chiara Moccia, Pamela Mongelos, Ana L Montealegre‐Páez, Francisca Morey Cortes, Alvaro Muñoz, Andy Ness, Aline B Neves, Marco Oliva, José Carlos de Oliveira, Hernán Ortiz, José Ortiz, Marta Osorio, Vanessa Ospina, Oliviero Ostellino, Mauricio Palau, Claire Paterson, Sonia Paytubi Casabona, Giancarlo Pecorari, David M Pereira, Olivia Pérol, Shahid Pervez, Alicia Pomata, Maja Popovic, Alisson Poveda, Carol P Prado, Kristina M Prager, Guglielmo Ramieri, Juliana NI Rego, Rui M Reis, Helene Renard, Umberto Ricardi, Giuseppe Riva, Frederic Rodilla, Ingrid Rodriguez, María I Rodríguez, Alastair Ross, Pierre‐Eric Roux, Tazeen Saeed Ali, Pierre Saintigny, Juan J Santivañez, Cristóvam Scapultampo‐Neto, Javier Segovia, Agenor Sena, Ricardo Serrano, Shachi J Sharma, Oliver Siefer, Stephanie Smart, Bruna P Sorroche, Cinthia Sosa, Juliana Souza de Oliveira, Antonella Stura, Steven Thomas, Oscar Torres, Sara Tous, Gonzálo Ucross, Adriana Valenzuela, José Roberto Vasconcelos de Podestá, Alex Whitmarsh, Sylvia Wright, Shaymaa Alwaheidi, Paul Brennan, Shama Virani, Al Ross, David I Conway   +196 more
wiley   +1 more source

Fatal ruxolitinib-related JC virus meningitis

Journal of NeuroVirology, 2017
We report a possible association between ruxolitinib and JC virus meningitis. A 72-year-old man with myelofibrosis started treatment with ruxolitinib. Fourteen days later, the patient presented to the emergency department with fever and nausea. HIV test was negative. Ruxolitinib was suspended.
Ballesta B, González H, Martín V, Ballesta J   +3 more
openaire   +6 more sources