Can Arginine Inhibit Insulin Aggregation? A Combined Protein Crystallography, Capillary Electrophoresis, and Molecular Simulation Study [PDF]
, 2018 The oligomeric state of the storage form of human insulin in the pancreas, which may be affected by several endogenous components of β-cell storage granules such as arginine, is not known.
Brzozowski, Andrzej M. +8 more
core +4 more sources
New insulin-like growth factor 1 (IGF-1) analogs for receptor studies and therapeutic applications [PDF]
, 2023 The insulin/IGF system is an evolutionary conserved network that includes three closely related peptide hormones (insulin, IGF-1 and IGF-2), three homologous tyrosine kinase receptors (IR-A, IR-B and IGF-1R), a distinct IGF-2 receptor (IGF-2R), and six ...
Lin, Jingjing
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Strategies and results in the development of insulin derivatives for the treatment of diabetes [PDF]
, 2023 The aim of this bachelor's thesis is to present insulin analogs and to analyse the direction of development of these organic compounds. The text contains basic information on this subject (e.g.
Pokorný, Štěpán
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Combinatorial Libraries of Bipodal Binders of the Insulin Receptor
ChemMedChem, Volume 19, Issue 11, June 3, 2024.Large combinatorial libraries of bipodal constructs with two distinct peptides were synthesized on resin beads and assessed for insulin receptor binding via antibodies and flow cytometry. The outcomes were characterized by robust non‐specific interactions.
Irena Selicharová +7 more
wiley +1 more source
Mono-\u3cem\u3eN\u3c/em\u3e-acyl-2,6-diaminopimelic Acid Derivatives: Analysis by Electromigration and Spectroscopic Methods and Examination of Enzyme Inhibitory Activity [PDF]
, 2014 Thirteen mono-N-acyl derivatives of 2,6-diaminopimelic acid (DAP)—new potential inhibitors of the dapE-encoded N-succinyl-l,l-diaminopimelic acid desuccinylase (DapE; EC 3.5.1.18)—were analyzed and characterized by infrared (IR) and nuclear magnetic ...
Buděšínský, Miloš +10 more
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Analysis of selected constitutive features of Pavel Novotný's poetics in the collections Zápisky z garsonky, Dědek and Procedura [PDF]
, 2023 Katedra české literaturyFaculty of EducationPedagogická ...
Podhorník, Jan
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Odchod významného rusisty [PDF]
, 2014 Dne 23. dubna 2013 utrpěla naše rusistika citelnou ztrátu: ve věku téměř 89 let odešel z kolektivu českých lingvistů známý brněnský rusista prof. PhDr.
Žaža, Stanislav
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Insulin-Insulin-like Growth Factors Hybrids as Molecular Probes of Hormone : Receptor Binding Specificity [PDF]
, 2016 Insulin, insulin-like growth factors 1 and 2 (IGF-1 and -2, respectively), and their receptors (IR and IGF-1R) are the key elements of a complex hormonal system that is essential for the development and functioning of humans. The C and D domains of IGFs (
Andrzej M. Brzozowski +14 more
core +2 more sources
, 2013 Import 26/06/2013V mé bakalářské práci se budu zabývat spojením dvou zdánlivě neslučitelných fenoménů, a to Geotechniky a Geocachingu. Tedy oborů, které mají rozdílnou rychlost v získávání popularity u občanů.
Jiráček, Petr
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Supplementary material for the article: Macháčková, K.; Chrudinová, M.; Radosavljević, J.; Potalitsyn, P.; Křížková, K.; Fábry, M.; Selicharová, I.; Collinsová, M.; Brzozowski, A. M.; Žáková, L.; et al. Converting Insulin-like Growth Factors 1 and 2 into High-Affinity Ligands for Insulin Receptor Isoform A by the Introduction of an Evolutionarily Divergent Mutation. Biochemistry 2018, 57 (16), 2373– 2382. https://doi.org/10.1021/acs.biochem.7b01260 [PDF]
, 2018 Supplementary material for: [https://doi.org/10.1021/acs.biochem.7b01260]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789 ...
Brzozowski, Andrzej M. +10 more
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