Results 271 to 280 of about 297,973 (327)

An update on the landscape of collagen bioactive fragments

The FEBS Journal, EarlyView.
The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley   +1 more source

proBDNF-SorCS2 Axis Suppresses Osteogenesis and Augments Inflammation of Human Periodontal Ligament Stem Cells in Inflammatory Conditions. [PDF]

Int Dent J
Pan L, Yang Y, Jia X, Zhao R, Wang Y, Guan X, Hou T.   +6 more
europepmc   +1 more source

Sacubitril/Valsartan Attenuates Inflammation and Fibrosis Associated With Decreased Integrin α8 and Inhibits Hepatocarcinogenesis in a Rat Model of Metabolic Dysfunction‐Associated Steatohepatitis

Hepatology Research, EarlyView.
Sacubitril/Valsartan (Sac/Val) alleviates fibrosis and inflammation in metabolic dysfunction‐associated steatohepatitis (MASH). Its anti‐fibrotic effect is linked to the suppression of Integrin alpha 8 (Itga8), a protein crucial for hepatic stellate cell (HSC) activation and collagen production.
Hayato Kawamura, Aya Naiki‐Ito, Xiaochen Kuang, Akihiro Murakami, Masayuki Komura, Takanori Suzuki, Hiroyuki Kato, Yuko Nagayasu, Kentaro Matsuura, Kei Fujiwara, Hiromi Kataoka, Satoru Takahashi   +11 more
wiley   +1 more source

High-Protein Diet Exacerbates Insulin Resistance via the JNK/IKKβ-IRS-1 Pathway. [PDF]

Endocrinol Diabetes Metab
Li J, Xu J, Tian J, Chen L, Zhao L, Yang Y, Wang J, Yan L, Yang Y, Jiang Y, Chen S, Wang B, Wang L, Yang X.   +13 more
europepmc   +1 more source

Melatonin and the Dental Pulp: A Scoping Review

International Endodontic Journal, EarlyView.
ABSTRACT Background In general medicine, melatonin is known to enhance wound healing and promote stem cell differentiation. Its potential relevance in endodontics, however, remains underexplored. Objectives This scoping review aimed to systematically assess the available evidence on the effects of melatonin (a) on dental pulp tissue and (b) on human ...
Jasmin Schäfer, Konrad Kleszczynski, Edgar Schäfer   +2 more
wiley   +1 more source

<i>Cynanchum wilfordii</i> modulates inflammatory responses in LPS-stimulated RAW264.7 cells via the NF-κB and MAPK pathways. [PDF]

J Enzyme Inhib Med Chem
Ji YJ, Kang MH, Han SH, Lee YS, Kim MJ, Kim JH, Jang GY.   +6 more
europepmc   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Correction to "The Interleukin-1α Stimulated Expression of the Wrinkle-Inducing Elastase Neprilysin in Adult Human Dermal Fibroblasts Is Mediated via the Intracellular Signaling Axis of ERK/JNK/c-Jun/c-Fos/AP-1". [PDF]

J Dermatol
europepmc   +1 more source

CAT/SOD-Enriched Achyranthes bidentata nanovesicles mitigate TMJOA via ROS scavenging and JNK/FOXO1 pathway Inhibition. [PDF]

J Nanobiotechnology
Li R, Huang Z, Kong L, Cai W, Li X, Hsieh C, Zheng K, Deng C, Cao W, Wu A, Pathak JL, Zhang R, Zhang Q.   +12 more
europepmc   +1 more source